Apolipoprotein E genotype and Alzheimer's disease in an elderly Norwegian cohort

Neurodegeneration

Volumn 5, Issue 1, 1996, Pages 43-47

  Benjamin, R ^a   Leake, A ^a   McArthur, F K ^a   Candy, J M ^a   Ince, P G ^a   Edwardson, J A ^a   Torvik, A ^c   Morris, C M ^a   Bjertness, R ^b  

^a NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OSLO   (Norway)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

Alzheimer's disease; Apolipoprotein E

Indexed keywords

APOLIPOPROTEIN E;

AGED; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; GENOTYPE; HUMAN; HUMAN TISSUE; NORWAY; NURSING HOME; ONSET AGE; PRIORITY JOURNAL;

EID: 0029930022     PISSN: 10558330     EISSN: None     Source Type: Journal    
DOI: 10.1006/neur.1996.0006     Document Type: Article

References (17)

1. Corder EH, Saunders AM, Stittmatter WJ, Schmechel DE, Gaskell PC, Rinnuler JB, Locke PA, Conneally PM, Schmader KE, Small GW, Rosses AD, Maines JL, Pericak-Vance MA (1994) Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer 's disease. Nature Genetics 7:180-184
2. Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA (1993) Gene dose of apolipoprotein E Type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923
3. Engedal K, Hangen PK (1993) The prevalence of dementia in a sample of elderly Norwegians Int J Geriatr Psychiat 8:565-570
4. Hixson JE, Vernier DT (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha I. Lipid Res 31:545-548
5. Hughes CP, Berg L, Danzinger WL, Coben LA, Martin RL (1982) A new clinical scale for the staging of dementia. Br J Psychiat 140:566-572
6. Ince PG, McArthur FK, BjertnessE, Torvik A, CandyJM, Edwardson JA (1995) Neuropathological diagnoses in elderly patients in Oslo: Alzheimer's disease, Lewy body disease, vascular lesions. Dementia 6: 162-168
7. Kounnas MZ, Moir RD, Rebeck GW, Bush AI, Argraves WS, Tanzi RE, Hyman BT, Strickland DK (1995) LDL receptor-related protein, a multifunctional Apo E receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell 82: 331-340
8. Lannfelt L, Lilius L, Nastase M, ViitanenM, Fratiglioni L, Eggertson G, Berglund L, Angelin B, Linder J, Winbald B, Basum H (1994) Lack of association between apolipoprotein E allele ε4 and sporadic Alzheimer's disease. Neurosci Lett 169:175-178
9. MaJ, Yee A, Brewer Jr HB, Das S, Potter H (1994) Amyloid-associated proteins α-1 antichymotrypsin and apolipoprotein E promote assembly of Alzheimer's β-protein into filaments. Nature 372:92-94
10. Mirra S, Heyman A, McKeel D (1991) The consortium to establish a registry for Alzheimer's disease (CERAD) Part II: Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41:479-486
11. Poirer J, Davignon J, Bouthillier D, Kogan S, Bertrand P, Gauthier S (1993) Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 342:697-699
12. Sanan DA, Weisgraber KH, Russel SJ, Mahley RW, Huang D, Saunders A, Schmechel D, Wisniewski T, Frangione B, Roses AD, Strittmatter WJ (1994) Apolipoprotein E associates with β-amyloid peptide of Alzheimer's disease to form novel monofibrils. J Clin Invest 94:860-869
13. Saunders AM, Strittmatter WJ, Schmechel D St Heorge Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, CrapperMcLachlan DR, Alberts MS, Hulette C, Grain B, Goldgaber D, Roses AD (1993) Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer 's disease. Neurology 43:1467-1472
14. Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD (1993a) Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer's disease. Proc Natl Acad Sci USA 90:1977-1981
15. Strittmatter WJ, Weisgraber KH, Huang DY, Dong L-M, Salvesen GS, Percak-Vance M, Schmechel D, Saunders AM, Goldgaber D, Roses AD (1993b) Binding of human apolipoprotein E to synthetic amyloid β-peptide: Isoform-specific effects and implications for late onset Alzheimer's disease. Proc Natl Acad Sci USA 90:8090-8102
16. Strittmatter WJ, Weisgraber KH, Goedert M, Saunders AM, Huang D, Corder EH, Dong L-M, Jakes R, Alberts MJ, Gilbert JR, Mau S-M, Hulete C, Einstein G, Schmechel E, Pericak-Vance M, Roses AD (1994) Hypothesis: Microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to Apolipoprotein E Genotype. Exp Neurol 1994; 125:163-171
17. Wenham PR, Price WH, Blundell G (1991) Apolipoprotein E genotyping by one-stage PCR. Lancet 337:1158-1159