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Volumn 61, Issue 10, 1996, Pages 1506-1512

Clinically relevant doses and blood levels produce experimental cyclosporine nephrotoxicity when combined with nitric oxide inhibition

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE METHYL ESTER; CYCLOSPORIN; NITRIC OXIDE;

EID: 0029929943     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199605270-00017     Document Type: Article
Times cited : (31)

References (54)
  • 1
    • 0024237509 scopus 로고
    • Chronic injury of human renal microvessels with low dose cyclosporine therapy
    • Myers BD, Newton L, Boshkos C, et al. Chronic injury of human renal microvessels with low dose cyclosporine therapy. Transplantation 1988; 46: 694.
    • (1988) Transplantation , vol.46 , pp. 694
    • Myers, B.D.1    Newton, L.2    Boshkos, C.3
  • 3
    • 0022585813 scopus 로고
    • Action and toxicity of cyclosporine
    • Bennett WM, Norman DJ. Action and toxicity of cyclosporine. Annu Rev Med 1986; 37: 215.
    • (1986) Annu Rev Med , vol.37 , pp. 215
    • Bennett, W.M.1    Norman, D.J.2
  • 4
    • 0025307489 scopus 로고
    • Chronic cyclosporine-associated nephrotoxicity in bone marrow transplant patients
    • Dieterle A, Gratwohl A, Nizze H, et al. Chronic cyclosporine-associated nephrotoxicity in bone marrow transplant patients. Transplantation 1990; 49: 1093.
    • (1990) Transplantation , vol.49 , pp. 1093
    • Dieterle, A.1    Gratwohl, A.2    Nizze, H.3
  • 5
    • 9344268886 scopus 로고    scopus 로고
    • Prevention of experimental cyclosporine-induced interstitial fibrosis by losartan and enalapril
    • in press
    • Burdmann EA, Andoh T, Nast C, et al. Prevention of experimental cyclosporine-induced interstitial fibrosis by losartan and enalapril. Am J Physiol (in press).
    • Am J Physiol
    • Burdmann, E.A.1    Andoh, T.2    Nast, C.3
  • 6
    • 0020463540 scopus 로고
    • Effect of cyclosporin on renin-angiotensin-aldosterone system
    • Siegal H, Ryffel B. Effect of cyclosporin on renin-angiotensin-aldosterone system. Lancet 1982; 2: 1274.
    • (1982) Lancet , vol.2 , pp. 1274
    • Siegal, H.1    Ryffel, B.2
  • 8
    • 0023916612 scopus 로고
    • Cyclosporine suppression of endothelial prostacyclin generation: A possible mechanism for nephrotoxicity
    • Voss BL, Hamilton KK, Samara ENS, McKee PA. Cyclosporine suppression of endothelial prostacyclin generation: a possible mechanism for nephrotoxicity. Transplantation 1988; 45: 793.
    • (1988) Transplantation , vol.45 , pp. 793
    • Voss, B.L.1    Hamilton, K.K.2    Samara, E.N.S.3    McKee, P.A.4
  • 9
    • 0024577289 scopus 로고
    • Effect of platelet-activating factor antagonist on cyclosporine nephrotoxicity
    • Pavao dos Santos OF, Boim MA, Bregman R, et al. Effect of platelet-activating factor antagonist on cyclosporine nephrotoxicity. Transplantation 1989; 47: 592.
    • (1989) Transplantation , vol.47 , pp. 592
    • Pavao Dos Santos, O.F.1    Boim, M.A.2    Bregman, R.3
  • 10
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelial-derived relaxing factor
    • Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelial-derived relaxing factor. Nature 1987; 327: 524.
    • (1987) Nature , vol.327 , pp. 524
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 11
    • 0024446417 scopus 로고
    • Cyclosporine treatment of normal rats produces a rise in blood pressure and decreased renal vascular responses to nerve stimulation, vasoconstrictors, and endothelial-dependent dilators
    • Gerkins JF. Cyclosporine treatment of normal rats produces a rise in blood pressure and decreased renal vascular responses to nerve stimulation, vasoconstrictors, and endothelial-dependent dilators. J Pharmacol Exp Ther 1989; 250: 1105.
    • (1989) J Pharmacol Exp Ther , vol.250 , pp. 1105
    • Gerkins, J.F.1
  • 12
    • 0028008789 scopus 로고
    • Mechanisms of the endothelial toxicity of cyclosporine A: Role of nitric oxide, cGMP, and Ca2+
    • Gallego M, Garcia Villalon AL, Lopez Farre AJ, et al. Mechanisms of the endothelial toxicity of cyclosporine A: role of nitric oxide, cGMP, and Ca2+. Circ Res 1994; 74: 477.
    • (1994) Circ Res , vol.74 , pp. 477
    • Gallego, M.1    Garcia Villalon, A.L.2    Lopez Farre, A.J.3
  • 13
    • 0026782496 scopus 로고
    • Chronic inhibition of nitric oxide synthesis: A new model of arterial hypertension
    • Ribeiro MO, Antunes E, deNucci G, Lovisolo SM, Zatz R. Chronic inhibition of nitric oxide synthesis: a new model of arterial hypertension. Hypertension 1992; 20: 298.
    • (1992) Hypertension , vol.20 , pp. 298
    • Ribeiro, M.O.1    Antunes, E.2    DeNucci, G.3    Lovisolo, S.M.4    Zatz, R.5
  • 14
    • 0026667091 scopus 로고
    • Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage
    • Baylis C, Mitruka B, Deng A. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest 1992; 90: 278.
    • (1992) J Clin Invest , vol.90 , pp. 278
    • Baylis, C.1    Mitruka, B.2    Deng, A.3
  • 18
    • 0023734808 scopus 로고
    • Long-term cyclosporin nephrotoxicity in the rat: Effects on renal function and morphology
    • Dieperink H, Leyssac PP, Starklint H, Kemp E. Long-term cyclosporin nephrotoxicity in the rat: effects on renal function and morphology. Nephrol Dial Transplant 1988; 3: 317.
    • (1988) Nephrol Dial Transplant , vol.3 , pp. 317
    • Dieperink, H.1    Leyssac, P.P.2    Starklint, H.3    Kemp, E.4
  • 20
    • 0025233949 scopus 로고
    • Chronic cyclosporine-induced nephropathy in the rat: A medullary ray and inner stripe injury
    • Rosen S, Greenfeld Z, Brezis M. Chronic cyclosporine-induced nephropathy in the rat: a medullary ray and inner stripe injury. Transplantation 1990; 49: 445.
    • (1990) Transplantation , vol.49 , pp. 445
    • Rosen, S.1    Greenfeld, Z.2    Brezis, M.3
  • 21
    • 0027647898 scopus 로고
    • Dissociation of glomerular filtration rate from tubulointerstitial fibrosis in experimental chronic cyclosporine-nephropathy: Role of sodium intake
    • Elzinga LW, Rosen S, Bennett WM. Dissociation of glomerular filtration rate from tubulointerstitial fibrosis in experimental chronic cyclosporine-nephropathy: role of sodium intake. J Am Soc Nephrol 1993; 4: 214.
    • (1993) J Am Soc Nephrol , vol.4 , pp. 214
    • Elzinga, L.W.1    Rosen, S.2    Bennett, W.M.3
  • 22
    • 0029154191 scopus 로고    scopus 로고
    • Cyclosporine A induced arteriolopathy in a art model of chronic cyclosporine nephropathy
    • in press
    • Young BA, Burdmann EA, Johnson RJ, et al. Cyclosporine A induced arteriolopathy in a art model of chronic cyclosporine nephropathy. Kidney Int (in press).
    • Kidney Int
    • Young, B.A.1    Burdmann, E.A.2    Johnson, R.J.3
  • 23
    • 0027522338 scopus 로고
    • Identification of increased nitric oxide biosynthesis during pregnancy in rats
    • Conrad KP, Joffe GM, Kruszyna H, et al. Identification of increased nitric oxide biosynthesis during pregnancy in rats. FASEB 1993; 7: 566.
    • (1993) FASEB , vol.7 , pp. 566
    • Conrad, K.P.1    Joffe, G.M.2    Kruszyna, H.3
  • 24
    • 0025079514 scopus 로고
    • Cyclosporine in vitro reduces endothelial-dependent relaxation to acetylcholine but does not affect relaxation to nitrovasodilators
    • Dihn Xuan AT, Fan TPD, Higenbottam TW, Wallwork J. Cyclosporine in vitro reduces endothelial-dependent relaxation to acetylcholine but does not affect relaxation to nitrovasodilators. Transplant Proc 1990; 22: 1723.
    • (1990) Transplant Proc , vol.22 , pp. 1723
    • Dihn Xuan, A.T.1    Fan, T.P.D.2    Higenbottam, T.W.3    Wallwork, J.4
  • 25
    • 0027471305 scopus 로고
    • Blockade of endothelium-dependent responses in conscious rats by cyclosporine A: Effect of L-Arg
    • Gallego MJ, Lopez Farre A, Riesco A, et al. Blockade of endothelium-dependent responses in conscious rats by cyclosporine A: effect of L-Arg. Am J Physiol 1993; 264: H708.
    • (1993) Am J Physiol , vol.264
    • Gallego, M.J.1    Lopez Farre, A.2    Riesco, A.3
  • 26
    • 0027931645 scopus 로고
    • Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity
    • Bobadilla NA, Tapia E, Franco M, et al. Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity. Kidney Int 1994; 46: 773.
    • (1994) Kidney Int , vol.46 , pp. 773
    • Bobadilla, N.A.1    Tapia, E.2    Franco, M.3
  • 27
    • 0026680275 scopus 로고
    • Renal effects of prolonged synthesis inhibition of endothelial-derived nitric oxide
    • Salazar FJ, Pinilla JM, Lopez F, Romero JC, Quesada T. Renal effects of prolonged synthesis inhibition of endothelial-derived nitric oxide. Hypertension 1993; 20: 113.
    • (1993) Hypertension , vol.20 , pp. 113
    • Salazar, F.J.1    Pinilla, J.M.2    Lopez, F.3    Romero, J.C.4    Quesada, T.5
  • 28
    • 0027466892 scopus 로고
    • Angiotensin blockade reverses hypertension during the long-term nitric oxide synthase inhibition
    • Pollack DM, Polakowski JS, Divish BJ, Opgenorth TJ. Angiotensin blockade reverses hypertension during the long-term nitric oxide synthase inhibition. Hypertension 1993; 21: 660.
    • (1993) Hypertension , vol.21 , pp. 660
    • Pollack, D.M.1    Polakowski, J.S.2    Divish, B.J.3    Opgenorth, T.J.4
  • 29
    • 0028322049 scopus 로고
    • Angiotensin II and alpha 1-adrenergic tone in chronic nitric oxide blockade-induced hypertension
    • Qui C, Engels K, Baylis C. Angiotensin II and alpha 1-adrenergic tone in chronic nitric oxide blockade-induced hypertension. Am J Physiol 1994; 266: R1470.
    • (1994) Am J Physiol , vol.266
    • Qui, C.1    Engels, K.2    Baylis, C.3
  • 30
    • 0027230953 scopus 로고
    • Sodium and angiotensin in hypertension induced by long-term nitric oxide blockade
    • Jover B, Herizi A, Ventre F, Dupont M, Mimran A. Sodium and angiotensin in hypertension induced by long-term nitric oxide blockade. Hypertension 1993; 21: 944.
    • (1993) Hypertension , vol.21 , pp. 944
    • Jover, B.1    Herizi, A.2    Ventre, F.3    Dupont, M.4    Mimran, A.5
  • 31
    • 0027522640 scopus 로고
    • Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney
    • Scholz H, Kurtz A. Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney. J Clin Invest 1993; 91: 1088.
    • (1993) J Clin Invest , vol.91 , pp. 1088
    • Scholz, H.1    Kurtz, A.2
  • 33
    • 0022649146 scopus 로고
    • Acute cyclosporine A nephrotoxicity in rats: Which role for renin-angiotensin system and glomerular prostaglandins?
    • Perico N, Benigni A, Bosco E, et al. Acute cyclosporine A nephrotoxicity in rats: which role for renin-angiotensin system and glomerular prostaglandins? Clin.Nephrol 1986; 25: S83.
    • (1986) Clin.Nephrol , vol.25
    • Perico, N.1    Benigni, A.2    Bosco, E.3
  • 35
    • 0023854871 scopus 로고
    • The long-term course of cyclosporine-associated chronic nephropathy
    • Myers BD, Sibley R, Newton L, et al. The long-term course of cyclosporine-associated chronic nephropathy. Kidney Int 1988; 33: 590.
    • (1988) Kidney Int , vol.33 , pp. 590
    • Myers, B.D.1    Sibley, R.2    Newton, L.3
  • 36
    • 0022369113 scopus 로고
    • Systematic hypertension after cardiac transplantation: Effect of cyclosporine on the renin-angiotensin-aldosterone system
    • Bellet M, Cabrol C, Sassano P, Leger P, Corvol P, Menard J. Systematic hypertension after cardiac transplantation: effect of cyclosporine on the renin-angiotensin-aldosterone system. Am J Cardiol 1985; 56: 927.
    • (1985) Am J Cardiol , vol.56 , pp. 927
    • Bellet, M.1    Cabrol, C.2    Sassano, P.3    Leger, P.4    Corvol, P.5    Menard, J.6
  • 37
    • 0023633295 scopus 로고
    • Suppression of plasma renin activity by cyclosporine
    • Bantle JP, Boudreau RJ, Ferris TF. Suppression of plasma renin activity by cyclosporine. Am J Med 1987; 83: 59.
    • (1987) Am J Med , vol.83 , pp. 59
    • Bantle, J.P.1    Boudreau, R.J.2    Ferris, T.F.3
  • 38
    • 0021193959 scopus 로고
    • The effect of salt intake on cyclosporine-induced impairment on renal in rats
    • Gerkins JF, Bhagwandeen SB, Dosen PJ, Smith AJ. The effect of salt intake on cyclosporine-induced impairment on renal in rats. Transplantation 1984; 38: 412.
    • (1984) Transplantation , vol.38 , pp. 412
    • Gerkins, J.F.1    Bhagwandeen, S.B.2    Dosen, P.J.3    Smith, A.J.4
  • 39
    • 0023026844 scopus 로고
    • Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla
    • Ingelfinger JR, Pratt RE, Ellison K, Dzau VJ. Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla. J Clin Invest 1986; 78: 1311.
    • (1986) J Clin Invest , vol.78 , pp. 1311
    • Ingelfinger, J.R.1    Pratt, R.E.2    Ellison, K.3    Dzau, V.J.4
  • 40
    • 0023789072 scopus 로고
    • Expression of the renin gene in extra-renal tissues of the rat
    • Samani NJ, Swales JD, Brammar WJ. Expression of the renin gene in extra-renal tissues of the rat. Biochem J 1988; 253: 907.
    • (1988) Biochem J , vol.253 , pp. 907
    • Samani, N.J.1    Swales, J.D.2    Brammar, W.J.3
  • 43
    • 0027275820 scopus 로고
    • Generation of oxygen free radicals during the metabolism of cyclosporine A: A cause-effect relationship with metabolism inhibition
    • Serino F, Grevel J, Napoli KL, Kahan BD, Strobel HW. Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition. Mol Cell Biochem 1993; 122: 101.
    • (1993) Mol Cell Biochem , vol.122 , pp. 101
    • Serino, F.1    Grevel, J.2    Napoli, K.L.3    Kahan, B.D.4    Strobel, H.W.5
  • 44
    • 0022861227 scopus 로고
    • Biotransformation and distribution in blood of cyclosporine and its metabolites
    • Maurer G, Lemaire M. Biotransformation and distribution in blood of cyclosporine and its metabolites. Transplant Proc 1986; 18(suppl 5): 25.
    • (1986) Transplant Proc , vol.18 , Issue.5 SUPPL. , pp. 25
    • Maurer, G.1    Lemaire, M.2
  • 45
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RJ, Palmer RMJ, Moncada S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 1986; 320: 454.
    • (1986) Nature , vol.320 , pp. 454
    • Gryglewski, R.J.1    Palmer, R.M.J.2    Moncada, S.3
  • 46
    • 0024536206 scopus 로고
    • The role for reactive oxygen species in cyclosporine A induced nephrotoxicity in rats
    • Kumano K, Yoshida K, Iwamura M, et al. The role for reactive oxygen species in cyclosporine A induced nephrotoxicity in rats. Transplant Proc 1989; 21: 941.
    • (1989) Transplant Proc , vol.21 , pp. 941
    • Kumano, K.1    Yoshida, K.2    Iwamura, M.3
  • 47
    • 0025033479 scopus 로고
    • Evidence that alteration in renal metabolism and lipid peroxidation may contribute to nephrotoxicity
    • Walker PD, Lazzaro VA, Duggin GG, Horvat JS, Tiller DJ. Evidence that alteration in renal metabolism and lipid peroxidation may contribute to nephrotoxicity. Transplantation 1990; 50: 487.
    • (1990) Transplantation , vol.50 , pp. 487
    • Walker, P.D.1    Lazzaro, V.A.2    Duggin, G.G.3    Horvat, J.S.4    Tiller, D.J.5
  • 48
    • 0026570225 scopus 로고
    • Inactivation of endothelial derived relaxing factor by oxidized lipoproteins
    • Chin JH, Azhar S, Hoffman BB. Inactivation of endothelial derived relaxing factor by oxidized lipoproteins. J Clin Invest 1992; 89: 10.
    • (1992) J Clin Invest , vol.89 , pp. 10
    • Chin, J.H.1    Azhar, S.2    Hoffman, B.B.3
  • 49
    • 0023932868 scopus 로고
    • Effect of cyclosporin A on cultured human kidney cells
    • Trifillis AL, Kahng MW. Effect of cyclosporin A on cultured human kidney cells. Transplant Proc 1988; 3(3): 717.
    • (1988) Transplant Proc , vol.3 , Issue.3 , pp. 717
    • Trifillis, A.L.1    Kahng, M.W.2
  • 50
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87: 1620.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 51
    • 0025363999 scopus 로고
    • Ischemic injury mediator
    • Beckman JS. Ischemic injury mediator. Nature 1990; 345: 27.
    • (1990) Nature , vol.345 , pp. 27
    • Beckman, J.S.1
  • 52
    • 0002832724 scopus 로고
    • Essential hypertension
    • Brenner BM, Rector FC (ed.), Philadelphia: Saunders
    • Laragh JH, Pickering TG. Essential hypertension, in Brenner BM, Rector FC (ed.), The kidney. Philadelphia: Saunders, 1991; 1909.
    • (1991) The Kidney , pp. 1909
    • Laragh, J.H.1    Pickering, T.G.2
  • 53
    • 0021073185 scopus 로고
    • Morphological findings in kidney transplants after treatment with cyclosporine
    • Mihatsch MJ, Thiel G, Spichtin HP, et al. Morphological findings in kidney transplants after treatment with cyclosporine. Transplant Proc 1983; XV(suppl 1): 2821.
    • (1983) Transplant Proc , vol.15 , Issue.1 SUPPL. , pp. 2821
    • Mihatsch, M.J.1    Thiel, G.2    Spichtin, H.P.3
  • 54
    • 9244241008 scopus 로고
    • Effects of in vivo cyclosporine administration on endothelium-dependent responses in isolated vascular rings
    • Chan BBK, Kern JA, Flanagan TL, Kron IL, Tribble CG. Effects of in vivo cyclosporine administration on endothelium-dependent responses in isolated vascular rings. Circulation 1992; 86: SII-295.
    • (1992) Circulation , vol.86
    • Chan, B.B.K.1    Kern, J.A.2    Flanagan, T.L.3    Kron, I.L.4    Tribble, C.G.5


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