Duration of action of intranasal atropine on methacholine-induced nasal secretions

Archives of Otolaryngology - Head and Neck Surgery

Volumn 122, Issue 3, 1996, Pages 321-323

  Baroody, Fuad M ^a,e   Driscoll, Peter V ^c   Moylan, Birgitta ^d   Fleming, Laura ^b   Shilstone, Jonathan ^b   Naclerio, Robert M ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Muro Pharmaceutical Inc   (United States)

^c LOUISIANA STATE UNIVERSITY   (United States)

^d JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; IPRATROPIUM BROMIDE; METHACHOLINE CHLORIDE; PLACEBO;

ADULT; ALLERGIC RHINITIS; ANTICHOLINERGIC EFFECT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG FORMULATION; FEMALE; HEADACHE; HUMAN; INTRANASAL DRUG ADMINISTRATION; MALE; NOSE MUCOSA; NOSE SECRETION; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; RHINORRHEA; XEROSIS;

EID: 0029929465     PISSN: 08864470     EISSN: None     Source Type: Journal    
DOI: 10.1001/archotol.1996.01890150091016     Document Type: Article

References (14)

1. Raphael GD, Baraniuk JN, Kaliner MA. How and why the nose runs J Allergy Clin Immunol. 1991;87:457-467.
2. Cauna N, Cauna D, Hinderer KH. Innervation of human nasal glands. J Neurocytol. 1972,1:49-60
3. Van Megen YJB, Klaassen ABM, Rodrigues de Miranda JF, van Ginneken CAM, Wentges BTR. Alterations of muscarinic acetylcholine receptors in the nasal mucosa of allergic patients in comparison with nonallergic individuals. J Allergy Clin Immunol 1991;87 521-529.
4. Brown JH. Atropine, scopolamine, and related antimuscarinic drugs. In: Goodman Gilman A, Rall TW, Nies AS, Taylor P, eds. Goodman and Gilman's: The Pharmacological Basis of Therapeutics. 8th ed Elmsford, NY: Pergamon Press Inc; 1990.150-165.
5. Baroody FM, Ford S, Lichtenstein LM, Kagey-Sobotka A, Naclerio RM Physiologic responses and histamine release after nasal antigen challenge. Am J Respir Crit Care Med 1994;149:1457-1465.
6. Philip G, Jankowski R, Baroody F, Naclerio RM, Togias AG. Reflex activation of nasal secretion by unilateral inhalation of cold dry air. Am Rev Respir Dis. 1993;148:1616-1622
7. Philip G, Baroody FM, Proud D, Naclerio RM, Togias AG. The human nasal response to capsaicin. J Allergy Clin Immunol. 1994;94:1035-1045.
8. Baroody FM, Wagenmann M Naclerio RM A comparison of the secretory response of the nasal mucosa to histamine and methacholine. J Appl Physiol 1993;74:2661-2671.
9. Wagenmann M, Baroody FM, Jankowski R, et al Onset and duration of action of ipratropium bromide nasal spray on methacholine induced nasal secretions Clin Exp Allergy. 1994,24:288-290.
10. Jackson RT, Teichgraeber J Low-dose topical atropine for rhinorrhea Arch Otolaryngol Head Neck Surg 1981;107.288-289.
11. Silvers WS. The skier's nose. Ann Allergy. 1991,67:32-36.
12. Borum P Nasal methacholine challenge. J Allergy Clin Immunol. 1979;63 253-257
13. Druce HM, Wright RH, Kossoff D, Kaliner MA. Cholinergic nasal hyperreactivity in atopic subiects J Allergy Clin Immunol. 1985;76:445-452.
14. Van Wijk GR, Dieges PH. Comparison of nasal responsiveness to histamine, methacholine and phentolamine in allergic rhinitis patients and controls. Clin Allergy. 1987;17:563-570