Design and synthesis of bisubstrate analogues for 3-hydroxy-3-methyl-glutaryl coenzyme A reductase

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 6, 1996, Pages 615-618

  Taillefumier, C ^a   De Fornel, D ^b   Chapleur, Y ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b Groupe Fournier   (France)

Author keywords

3 hydroxy 3 methyl glutaryl coenzyme A reductase; cholesterol biosynthesis; multisubstrate analogue; NADPH

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ARTICLE; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME SUBSTRATE; STEREOCHEMISTRY;

EID: 0029929293     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00077-7     Document Type: Article

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