Tissue-specific expression of a Ca2+-activated K+ channel is controlled by multiple upstream regulatory elements

Journal of Neuroscience

Volumn 16, Issue 5, 1996, Pages 1827-1835

  Brenner, Robert ^a   Thomas, Tarita O ^a   Becker, Marie N ^a   Atkinson, Nigel S ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Ca2+ activated K+ channel; Drosophila; Gene regulation; Reporter gene; Slowpoke; Tissue specific expression

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CHANNEL GATING; DROSOPHILA; GENE CONTROL; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; TISSUE SPECIFICITY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALCIUM; CENTRAL NERVOUS SYSTEM; DROSOPHILA MELANOGASTER; GENE DELETION; GENE EXPRESSION; GENES, REGULATOR; INTESTINES; MOLECULAR SEQUENCE DATA; MUSCLES; POTASSIUM CHANNELS; PROMOTER REGIONS (GENETICS); TRACHEA; TRANSCRIPTION, GENETIC;

EID: 0029928668     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-05-01827.1996     Document Type: Article

References (43)

1. Atkinson NS, Robertson GA, Ganetzky B (1991) A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science 253:551-555.
2. - channel mRNA in vitro and in vivo. Receptors Channels 1:287-293.
3. Becker MN, Brenner R, Atkinson NS (1995) Tissue-specific expression of a Drosophila calcium-activated potassium channel. J Neurosci 15:6250-6259.
4. Bosma MM, Allen ML, Martin TM, Tempel BL (1993) PKA-dependent regulation of mKv1.1, a mouse Shaker-like potassium channel gene, when stably expressed in CHO cells. J Neurosci 13:5242-5250.
5. Butler A, Tsunoda S, McCobb DP, Wei A, Salkoff L (1993) mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science 261:221-224.
6. Cavener DR (1987) Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res 15:1353-1361.
7. Conaway RC, Conaway TW (1994) Transcription mechanisms and regulation. New York: Raven.
8. Dworetzky SI, Trojnacki JT, Gribkoff VK (1994) Cloning and expression of a human large-conductance calcium-activated potassium channel. Brain Res 27:189-193.
9. Gossett LA, Kelvin DJ, Sternberg EA, Olson EN (1989) A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes. Mol Cell Biol 9:5022-5033.
10. Grayson J, Williams RS, Yu YT, Bassel-Duby R (1995) Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter. Mol Cell Biol 15:1870-1878.
11. Hoshi T, Zagotta WN, Aldrich RW (1990) Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250:533-538.
12. Jackson IJ (1991) A reappraisal of non-consensus mRNA splice sites. Nucleic Acids Res 19:3795-3798.
13. Javahery R, Khachi A, Lo K, Zenzie-Gregory B, Smale ST (1994) DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol Cell Biol 14:116-127.
14. Kikuchi T, Raju K, Breitman ML, Shinohara T (1993) The proximal promoter of the mouse arrestin gene directs gene expression in photoreceptor cells and contains an evolutionary conserved retinal factor-binding site. Mol Cell Biol 13:4400-4408.
15. Kirschman JA, Cramer JH (1988) Two new tools: multipurpose cloning vectors that carry kanamycin or spectinomycin/streptomycin resistance markers. Gene 68:163-165.
16. Kraner SD, Chong JA, Tsay H-J, Mandel G (1992) Silencing the type II sodium channel gene: a model for neural-specific gene regulation. Neuron 9:37-44.
17. Lagrutta A, Shen K-Z, North RA, Adelman JP (1994) Functional differences among alternatively spliced variants of slowpoke, a Drosophila calcium-activated potassium channel. J Biol Chem 269:20347-20351.
18. Latorre R, Oberhauser A, Labarca P, Alvarez O (1989) Varieties of calcium-activated potassium channels. Annu Rev Physiol 51:385-389.
19. Lilly B, Galewsky S, Firulli AB, Schulz RA, Oison EN (1994) D-MEF2: a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. Proc Natl Acad Sci USA 91:5662-5666.
20. - channel development in embryonic Xenopus laevis skeletal muscle. J Physiol (Lond) 480:405-410.
21. Lundell MJ, Hirsh J (1992) The zfh-2 gene product is a potential regulator of neuron-specific dopa decarboxylase gene expression in Drosophila. Dev Biol 154:84-94.
22. Mackler SA, Eberwine JH (1994) Cellular adaptation to opiates alters ion-channel mRNA levels. Proc Natl Acad Sci USA 91:385-389.
23. Mandel G, McKinnon D (1993) Molecular basis of neural-specific gene expression. Annu Rev Neurosci 16:323-345.
24. Manning G, Krasnow MA (1993) Development of the Drosophila tracheal system. In: The development of Drosophila melanogaster (Bate M, Martinez-Anas A, eds). pp 609-685. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
25. Matsubara H, Suzuki J, Inada M (1993) Shaker-related potassium channel, Kv1.4, mRNA regulation in cultured rat heart myocytes and differential expression of Kv1.4 and Kv1.5 genes in myocardial development and hypertrophy. J Clin Invest 92:1659-1666.
26. Mismer D, Rubin GM (1987) Analysis of the promoter of the ninaE opsin gene in Drosophila melanogaster. Genetics 116:565-578.
27. Moore MJ, Query CC, Sharp PA (1993) Splicing of precursors to mRNA by the spliceosome. In: The RNA world (Gesteland RF, Atkins JF, eds), pp 303-357. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
28. Mori Y, Matsubara H, Folco E, Siegel A, Koren G (1993) The transcription of a mammalian voltage-gated potassium channel is regulated by cAMP in a cell-specific manner. J Biol Chem 268:26482-26493.
29. Pallanck L, Ganetzky B (1994) Cloning and characterization of human and mouse homologs of the Drosophila calcium-activated potassium channel gene, slowpoke. Hum Mol Genet 3:1239-1243.
30. + channel genes. Semin Neurosci 5:135-145.
31. Revest PA, Abbott NJ (1992) Membrane ion channels of endothetial cells. Trends Pharmacol Sci 13:404-407.
32. Roberds SL, Tamkun MM (1991) Developmental expression of cloned cardiac potassium channels. FEBS Lett 284:152-154.
33. Rudy B (1988) Diversity and ubiquity of K channels. Neuroscience 25:729-749.
34. Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
35. + channel subunit proteins. Neuron 14:625-33.
36. Sheng Z-H, Zhang H, Barchi RL, Kallen RG (1994) Molecular cloning and functional analysis of the promoter of rat skeletal muscle voltage-sensitive sodium channel subtype 2 (rSkM2): evidence for muscle-specific nuclear protein binding to the core promoter. DNA Cell Biol 13:9-23.
37. Sontheimer H (1994) Voltage-dependent ion channels in glial cells. Glia 11:156-172.
38. Spradling AC (1986) P-element mediated transformation. In: Drosophila: a practical approach (Roberts DB, ed), pp 175-196. Oxford: IRL.
39. Thummel CS, Boulet AM, Lipshitz HD (1988) Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. Gene 74:445-456.
40. Toro L, Amador M, Stefani F. (1990) ANG II inhibits calcium-activated potassium channels from coronary smooth muscle in lipid bilayers. Am J Physiol 258:H912-H915.
41. + channel isoforms from human brain. Neuron 13:1315-1330.
42. von Heijne G (1994) Signals for protein targeting into and across membranes. In: Subcellular biochemistry, Vol 22, Membrane biogenesis (Maddy AH, Harris JR, eds), pp 1-19. New York: Plenum.
43. Yu Y-T, Nadal-Ginard B (1989) Interaction of nuclear proteins with a positive cis-acting element of rat embryonic myosin heavy-chain promoter: identification of a new transcriptional factor. Mol Cell Biol 9:1839-1849.