The levels of repair of endonuclease III-sensitive sites, 64 photoproducts and cyclobutane pyrimidine dimers differ in a point mutant for RAD14, the Saccharomyces cerevisiae homologue of the human gene defective in XPA patients

Molecular and General Genetics

Volumn 250, Issue 4, 1996, Pages 515-522

  Reed, Simon H ^a   McCready, Shirley ^b   Boiteux, Serge ^c   Waters, Raymond ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Nucleotide excision repair; RAD14; Saccharomyces cerevisiae; XPA homologue

Indexed keywords

CYCLOBUTANE; ENDONUCLEASE III; NUCLEOTIDE; PYRIMIDINE DIMER; UNCLASSIFIED DRUG;

ARTICLE; DNA REPAIR; EXCISION REPAIR; MUTANT; NONHUMAN; PHOTOPRODUCT; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; XERODERMA PIGMENTOSUM;

DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA REPAIR; DNA, FUNGAL; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; FUNGAL PROTEINS; GENES, FUNGAL; HUMANS; POINT MUTATION; PYRIMIDINE DIMERS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; SEQUENCE HOMOLOGY, NUCLEIC ACID; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

EID: 0029928501     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02174040     Document Type: Article

References (28)

1. Asahara H, Wistort PM, Bank JF, Bakerian RH, Cunningham RP (1989) Purification and characterisation of E. coli endonuclease III from the cloned nth gene. Biochemistry 28:4444-4449
2. Bankmann M, Prakash L, Prakash S (1992) Yeast RAD14 and human xeroderma pigmentosum group A DNA-repair genes encode homologous proteins. Nature 355:555-558
3. Bohr VA, Smith CA, Okumoto DS, Hanawalt PC (1985) DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell 40:359-369
4. Boiteux S (1993) Properties and biological functions of the Nth and Fpg proteins of Escherichia coli: two DNA glycosylases that repair oxidative damage in DNA. Photochem Photobiol 19:87-96
5. Campbell I, Dufus JH (1988) Yeast: a practical approach. IRL Press, Oxford
6. Cleaver JE, Cortes F, Lutze LH, Morgan WF, Player AN, Vuksanovic L, Mitchell DL (1988) Unique DNA repair properties of a xeroderma pigmentosum revertant. Mol Cell Biol 7:3353-3357
7. Cleaver JE, McDowell MM, Jones C, Wood R, Karenz D (1994) Mutation and expression of the XPA gene in revertants and hybrids of a xeroderma pigmentosum cell line. Somatic Cell Mol Genet 20:327-337
8. Deschavanne PJ, Chavaudra N, Fertil B, Malaise EP (1984) Abnormal sensitivity of some Cockayne's syndrome cell strains to UV- and gamma-rays. Association with a reduced ability to repair potentially lethal damage. Mutation Research 131:61-70
9. Guzder SN, Sung P, Prakash L, Prakash S (1993) Yeast DNA-repair gene RAD14 encodes a zinc metalloprotein with affinity for ultraviolet-damaged DNA. Proc Nat Acad Sci USA 90:5433-5437
10. Hoeijmakers JHJ (1993) Nucleotide excision repair II. From yeast to mammals. Trends Genet 9:211-217
11. Leadon SA, Lawrence DA (1992) Strand-selective repair of DNA damage in the yeast GAL7 gene requires RNA polymerase II. J Biol Chem 267:23175-23182
12. Leadon SA, Cooper PK (1993) Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome. Proc Nat Acad Sci USA 90:10499-10503
13. Lehmann AR, Norris PG (1989) DNA repair and cancer: speculations based on studies with xeroderma pigmentosum, Cockayne's syndrome and trichothiodtstrophy. Carcinogenesis 10:1353-1356
14. McCready S (1994) Repair of 6-4 photoproducts and cyclobutane pyrimidine dimers in rad mutants of Saccharomyces cerevisiae. Mutation Res 315:261-273
15. McCready S, Cox B (1993) Repair of 6-4 photoproducts in Saccharomyces cerevisiae. Mutation Res 293:233-240
16. McDowell ML, Nguyen T, Cleaver JE (1993) A single-site mutation in the XPAC gene alters photoproduct recognition. Mutagenesis 8:155-161
17. Nakabeppu YK, Yamashita K, Sekiguchi M (1982) Purification and characterization of normal and mutant forms of T4 endonuclease V. J Biol Chem 257:2556-2562
18. Prakash S, Sung P, Prakash L (1993) DNA repair genes and proteins of Saccharomyces cerevisiae. Annu Rev Genet 27:33-70
19. Reed SH, Boiteux S, Waters R (1996) UV-induced endonuclease III-sensitive sites at the mating type loci in Saccharomyves cerevisie are repaired by nucleotide excision repair: RAD7 and RAD16 are not required for their removal from HMLα. Mol Gen Genet 250:505-514
20. Reynolds RJ, Friedberg EC (1981) Molecular mechanisms of pyrimidine dimer excision in Saccharomyces cerevisiae: incision of ultraviolet-irradiated deoxyribonucleic acid in vivo. J Bacteriol 146:692-704
21. Sherman F, Fink GR, Hicks JB (1986) Methods in yeast genetics, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
22. Svejstrup JQ, Wang Z, Feaver WJ, Wu X, Bushnell DA, Donahue TF, Friedberg EC, Kornberg RD (1995) Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 80:21-28
23. Sweden KS, Hanawalt PC (1992) Preferential repair of cyclobutane pyrimidine dimers in the transcribed strand of a gene in yeast chromosomes and plasmids is dependent on transcription. Proc Nat Acad Sci USA 89:10696-10700
24. Tanaka K, Miura N, Satokata I, Miyamoto I, Yoshida MC, Satoh, Y, Kondo S, Yasui A, Okayama H, Okada Y (1990) Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. Nature 348:73-76
25. Terleth C (1990) Differential DNA repair of UV damage in the yeast Saccharomyces cerevisiae. Ph.D. thesis. University of Leiden
26. Terleth C, Vansluis C, Van de Putte P (1989) Differential repair of UV damage in S. cerevisiae. Nucleic Acids Res 17:4433-4439
27. Venema J, Mullenders LHF, Natarajan AT, van Zeeland AA, Mayne LV (1990) The genetic defect in Cockayne Syndrome is associaled with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc Nat Acad Sci USA 87: 4707-4711
28. Wilcox DR, Prakash L (1981) Incision and postincision steps of pyrimidine dimer removal in excision-defective mutants of Saccharmnyces cerevisiae. J Bacteriol 148:618-623