A high performance liquid chromatographic method for a novel serotonin reuptake inhibitor 5-chloro-2-[[2-(dimethylamino)methyl]phenyl]benzyl alcohol (403U76)

Journal of Liquid Chromatography and Related Technologies

Volumn 19, Issue 7, 1996, Pages 1117-1126

  Silver, Ivin S ^a   Wurm, Robert M ^a   Welch, Richard M ^a   Harrelson, Jane Croft ^a  

^a Burroughs Wellcome Co   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

336U76; 403U76; 5 CHLORO 2 [[2 (DIMETHYLAMINO)METHYL]PHENYL]BENZYL ALCOHOL; 515U88; BIPENAMOL; DRUG METABOLITE; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; RAT; TECHNIQUE; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALIA;

EID: 0029928451     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1080/10826079608006306     Document Type: Article

References (5)

1. R. M. Ferris, L. Brieaddy, N. Mehta, E. Hollingsworth, G. Rigdon, C. Wang, F. Soroko, W. Wastila, B. Cooper. "Pharmacological Properties Of 403U76: A New Chemical Class Of Selective Serotonin Reuptake Inhibitor. (Submitted).
2. J. Mendels. "Clinical Experience With Serotonin Reuptake Inhibiting Antidepressants." J. Clin. Psychiatry, 48, (3 Suppl), 26-30 (1987).
3. G. D. Burrows, I. M. McIntyre, F. K. Judd, T. R. Norman. "Clinical Effects Of Serotonin Reuptake Inhibitors In The Treatment Of Depressive Illness." J. Clin. Psychiatry, 49, (8 Suppl), 18-22 (1988).
4. G. Curzon. "Serotonergic Mechanism Of Depression." Clin. Neuropharmacology," 11, (2 Suppl), S11-S20 (1988).
5. I. S. Silver. Personal Communication.