The ankyrin repeats but not the PEST-like sequences are required for signal-dependent degradation of IκBα

Oncogene

Volumn 12, Issue 5, 1996, Pages 1159-1164

  Aoki, Tsutomu ^a   Sano, Yuji ^a   Yamamoto, Tadashi ^a   Inoue, Jun Ichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Ankyrin repeats; Degradation; I B; PEST sequence; Phosphorylation

Indexed keywords

ANKYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANKYRINS; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; REPETITIVE SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION;

EID: 0029928404     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Alkalay I, Yaron A, Hatzubai A, Jung S, Avraham A, Gerlitz O, Pashut-Lavon I and Ben-Neriah Y. (1995). Mol. Cell. Biol., 15, 1294-1301.
2. Baeuerle PA and Baltimore D. (1988). Science, 242, 540-546.
3. Baeuerle PA and Henkel T. (1994). Annu. Rev. Immunol., 12, 141-179.
4. Beg AA, Finco TS, Nantermet PV and Baldwin AS Jr. (1993). Mol. Cell. Biol., 13, 3301-3310.
5. Beg AA, Ruben SM, Scheinman RI, Haskill S, Rosen CA and Baldwin AS Jr. (1992). Genes Dev., 6, 1899-1913.
6. Belvin MP, Jin Y and Anderson KV. (1995). Genes Dev., 9, 783-793.
7. Berberich I, Shu GL and Clark EA. (1994). J. Immunol., 153, 4357-4366.
8. Bours V, Franzoso G, Azarenko V, Park S, Kanno T, Brown K and Sienbenlist U. (1993). Cell, 72, 729-739.
9. Brown K, Gerstberger S, Carlson L, Franzoso G and Siebenlist U. (1995). Science, 267, 1485-1488.
10. Brockman JA, Scherer DC, McKinsey TA, Hall SM, Qi X, Lee WY and Ballard DW. (1995). Mol. Cell. Biol., 15, 2809-2818.
11. Chen Z, Hagler J, Palombella VJ, Melandri F, Scherer D, Ballard D and Maniatis T. (1995). Genes Dev., 9, 1586-1597.
12. Cordle SR, Donald R, Read MA and Hawiger J. (1993). J. Biol. Chem., 268, 11803-11810.
13. Davis N, Ghosh S, Simmons DL, Tempst P, Liou H-C, Baltimore D and Bose HR Jr. (1991). Science, 253, 1268-1271.
14. DiDonato JA, Mercurio F and Karin M. (1995). Mol. Cell. Biol., 15, 1302-1311.
15. Ernst MK, Dunn LL and Rice NR. (1995). Mol. Cell. Biol., 15, 872-882.
16. Finco TS, Beg AA and Baldwin AS Jr. (1994). Proc. Natl. Acad. Sci. USA, 91, 11884-11888.
17. Ganchi PA, Sun S-C, Greene WC and Ballard DW. (1992). Mol. Biol. Cell, 3, 1339-1352.
18. Haskill S, Beg AA, Tompkins SM, Morris JS, Yurochko AD, Sampson-Johannes A, Mondai K, Ralph P and Baldwin AS Jr. (1991). Cell, 65, 1281-1289.
19. Hatada EN, Naumann M and Scheidereit C. (1993). EMBO J., 12, 2781-2788.
20. Hatada EN, Nieters A, Wulczyn FG, Naumann M, Meyer R, Nucifora G, McKeithan TW and Scheidereit C. (1992). Proc. Natl. Acad. Sci. USA, 89, 2489-2493.
21. Henkel T, Machleidt T, Alkalay I, Krönke M, Ben-Neriah Y and Baeuerle PA. (1993). Nature, 365, 182-185.
22. Henkel T, Zabel U, van Zee K, Müller JM, Fanning E and Baeuerle PA. (1992). Cell, 68, 1121-1133.
23. Inoue J-i, Kerr LD, Kakizuka A and Verma IM. (1992a). Cell, 68, 1109-1120.
24. Inoue J-i, Kerr RD, Rashid D, Davis N, Bose HR Jr and Verma IM. (1992b) Proc. Natl. Acad. Sci. USA, 89, 4333-4337.
25. Jaffray E, Wood KM and Hay RT. (1995). Mol. Cell. Biol., 15, 2166-2172.
26. Kunkel TA, Roberts JD and Zakour RA. (1987). Methods Enzymol., 154, 367-382.
27. Lin Y-C, Brown K and Siebenlist U. (1955). Proc. Natl. Acad. Sci. USA, 92, 552-556.
28. de Martin R, Vanhove B, Cheng Q, Hofer E, Csizmadia V, Winkler H and Bach FH. (1993). EMBO J., 12, 2773-2779.
29. Mellits KH, Hay RT and Goodbourn S. (1993). Nucleic Acids Res., 21, 5059-5066.
30. Miyamoto S, Maki M, Schmitt MJ, Hatanaka M and Verma IM. (1994). Proc. Natl. Acad. Sci. USA, 91, 12740-12744.
31. Osborn L, Kunkel S and Nabel GJ. (1989). Proc. Natl. Acad. Sci. USA, 86, 2336-2340.
32. Palombella VJ, Rando OJ, Goldberg AL and Maniatis T. (1994). Cell, 78, 773-785.
33. Rice NR and Ernst MK. (1993). EMBO J., 12, 4685-4695.
34. Rice NR, MacKichan ML and Israël A. (1992). Cell, 71, 243-253.
35. Rodriguez MS, Michalopoulos I, Arenzana-Seisdedos F and Hay RT. (1995). Mol. Cell. Biol., 15, 2413-2419.
36. Rogers S, Wells R and Rechsteiner M. (1986). Science, 234, 364-368.
37. Scott ML, Fujita T, Liou H-C, Nolan GP and Baltimore D. (1993). Genes Dev., 7, 1266-1276.
38. Sun S-C, Ganch PA, Ballard DW and Greene WC. (1993). Science, 259, 1912-1915.
39. Tewari M, Dobrzanski P, Mohn KL, Cressman DE, Hsu J-C, Bravo R and Taub R. (1992). Mol. Cell. Biol., 12, 2898-2908.
40. Traenckner EB-M, Wilk S and Baeuerle PA. (1994). EMBO J., 13, 5433-5441.
41. Traenckner EB-M, Pahl HL, Henkel T, Schmidt KN, Wilk S and Baeuerle PA. (1995). EMBO J., 14, 2876-2883.
42. Whiteside ST, Ernst MK, LeBail O, Laurent-Winter C, Rice N and Israël A. (1995). Mol. Cell. Biol., 15, 5339-5345.
43. Zabel U, Henkel T, Silva MS and Baeuerle PA. (1993). EMBO J., 12, 201-211.