The bronchodilatory effect of 7, 9′, 7′, 9-Bisepoxylignans on guinea-pig isolated trachea

Natural Product Letters

Volumn 8, Issue 3, 1996, Pages 159-161

  Miyazawa, Mitsuo ^a   Kasahara, Hiroyuki ^a   Kameoka, Hiromu ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

7, 9 , 7 , 9 bisepoxylignan; Bronchodilator; Guinea pig; Trachea

Indexed keywords

7,9',7',9 BISEPOXYLIGNAN; AMINOPHYLLINE; DE O METHYLMAGNOLIN; DE O METHYLYANGABIN; EPIMAGNOLIN; EUDESMIN; LIGNAN DERIVATIVE; MAGNOLIN; PHILLYGENIN; PINORESINOL; UNCLASSIFIED DRUG; YANGAMBIN;

ANIMAL TISSUE; ARTICLE; BRONCHODILATING ACTIVITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; GUINEA PIG; NONHUMAN; SMOOTH MUSCLE RELAXATION; TRACHEA;

EID: 0029927937     PISSN: 10575634     EISSN: None     Source Type: Journal    
DOI: 10.1080/10575639608044888     Document Type: Article

References (8)

1. Tsuruga, T., Ebizuka, Y., Nakajima, J., Chun, Y.-T., Noguchi, H., Iitaka, Y. and Sankawa, U. (1991) Chem. Pharm. Bull. 39, 3265.
2. MacRae, W. D. and Towers, G. H. N. (1984) Phytochemistry 23, 1207.
3. Nikaido, T., Ohtomo, T., Kinoshita, T., Sankawa, U., Nishibe, S. and Hisada, S. (1981) Chem. Pharm. Bull. 29, 3586.
4. Miyazawa, M., Kasahara, H. and Kameoka, H. (1993) Phytochemistry 34, 1501.
5. Miyazawa, M., Kasahara, H. and Kameoka, H. (1995) Phytochemistry 39, 1027.
6. Miyazawa, M., Kasahara, H. and Kameoka, H. (1993) Phytochemistry 32, 1421.
7. 50 values (concentration producing 50% of the maximal response) were calculated using linear regression analysis applied to the linear portion of each dose-response curve. Test compounds were dissolved in DMSO.
8. Miyazawa, M., Ishikawa, Y., Kasahara, H., Yamanaka, J. and Kameoka, H. (1993) Phytochemistry 35, 611.