Factor VII hyperactivity and endothelial cell damage are found in elderly hypertensives only when concomitant with microalbuminuria

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 3, 1996, Pages 455-461

  Kario, Kazuomi ^a,b,e   Matsuo, Takefumi ^b   Kobayashi, Hiroko ^b   Matsuo, Miyako ^b   Sakata, Toshiyuki ^c   Miyata, Toshiyuki ^c   Shimada, Kazuyuki ^d  

^a Awaji Hokudan Public Clinic   (Japan)

^b HYOGO PREFECTURAL AWAJI HOSPITAL   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

^e NONE   (Japan)

Author keywords

elderly; endothelial cell damage; factor VII; hypertension; microalbuminuria

Indexed keywords

ALBUMIN; BLOOD CLOTTING FACTOR 7; COAGULATING AGENT; FIBRINOGEN; THROMBOMODULIN; VON WILLEBRAND FACTOR;

AGED; AMBULATORY MONITORING; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; FEMALE; HEMOSTASIS; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; PRIORITY JOURNAL;

EID: 0029927932     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.3.455     Document Type: Article

References (37)

1. Meade TW. The epidemiology of atheroma, thrombosis and ischaemic heart disease. In: Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD, eds. Haemostasia and Thrombosis. London, UK: Churchill Livingstone Inc; 1994:1199-1227.
2. Donders SHJ, Lustermans FAT, van Wersch JWJ. Low order correlations of lipoprotein(a) with other blood lipids and with coagulation and fibrinolysis parameters in hypertensive and diabetic patients. Blood Coagul Fibrinolysis. 1992;3:249-256.
3. Phillips GB, Jing T-Y, Resnick LM, Barbagallo M, Laragh JH, Sealey JE. Sex hormones and hemostatic risk factors for coronary heart disease in men with hypertension. J Hypertens. 1993;11: 699-702.
4. Pedrinelli R, Giampietro O, Carmassi F, Melillo E, Dell'Omo G, Catapano G, Matteucci E, Talarico L, Morale M, De Negri F, Di Bello V. Microalbuminuria and endothelial dysfunction in essential hypertension. Lancet. 1994;344:14-18.
5. Yudkin JS, Forrest RD, Jackson CA. Microalbuminuria as predictor of vascular disease in non-diabetic subjects: Islington Diabetes Survey. Lancet. 1988;2:530-533.
6. Damsgaard EM, Frøland A, JØrgensen OD, Mogensen CE. Micro-albuminuria as predictor of increased mortality in elderly people. Br Med J. 1990;300:297-300.
7. Høegholm A, Bang LE, Kristensen KS, Nielsen JW, Holm J. Micro-albuminuria in 411 untreated individuals with established hypertension, white coat hypertension, and normotension. Hypertension. 1994;24:101-105.
8. Haffner SM, Stern MP, Gruber MKK, Hazuda HP, Mitchell BD, Patterson JK. Microalbuminuria: potential marker for increased cardiovascular risk factors in nondiabetic subjects? Arteriosclerosis. 1990;10:727-73l.
9. Pedrinelli R, Di Bello V, Catapano G, Talarico L, Materazzi F, Santoro G, Giusti C, Mosca F, Melillo E, Ferrari M. Microalbuminuria is a marker of left ventricular hypertrophy but not hyperinsulinemia in nondiabetic atherosclerotic patients. Arterioscler Thromb. 1993;13:900-906.
10. Gross P, Promax H, Durandet P, Clementy J. 'White coat' hypertension: no harm for the heart. Hypertension. 1993;22:766-770.
11. Shimada K, Kawamoto A, Matsubayashi K, Ozawa T. Silent cerebrovascular disease in the elderly: correlation with ambulatory pressure. Hypertension. 1990;16:692-699.
12. Pickering TG. White coat hypertension. In: Laragh H, Brenner BM, eds. Hypertension: Pathology, Diagnosis, and Management. 2nd ed. New York, NY: Raven Press Ltd; 1995:1913-1927.
13. Rapaport SI, Rao LVM. Initiation and regulation of tissue factordependent blood coagulation. Arterioscler Thromb. 1992;12: 1111-1121.
14. Meade TW, Mellows S, Brozovic M, Miller GJ, Chakrabarti RR, North WRS, Haines AP, Stirling Y, Imeson JD, Thompson SG. Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart Study. Lancet. 1986;2:533-537.
15. Orlando M, Leri O, Macioce G, Mattia G, Ferri GM. Factor VII in subjects at risk for thromboembolism: activation or increased synthesis? Haemostasia. 1987;17:340-343.
16. Huffman C, Shah A, Sodums M, Hultin MB. Factor VII activity state in coronary artery disease. J Lab Clin Med. 1988;111:475-481.
17. Kario K, Matsuo T, Nakao K. Factor VII hyperactiyity in the elderly. Thromb Haemost. 1991;65:25-27.
18. Kario K, Matsuo T. Coronary artery disease and factor VII hyper-activity in elderly Japanese. Am J Cardiol. 1992;69:807-809.
19. Meade TW, Ruddock V, Stirling Y, Chakrabarti R, Miller GJ. Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study. Lancet. 1993;342:1076-1079.
20. Morrisscy JH, Macik BG, Neuenschwander PF, Comp PC. Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation. Blood. 1993;81:734-744.
21. Wildgoose P, Nemerson Y, Hansen LL, Nielsen FE, Glazer S, Hedner U. Measurement of basal levels of factor Vila in hemophilia A and B patients. Blood. 1992;80:25-28.
22. Kario K, Miyata T, Sakata T, Matsuo T, Kato H. Fluorogenic assay of activated factor VII: plasma factor Vila levels in relation to arterial cardiovascular diseases in Japanese. Arterioscler Thromb. 1994;14:265-274.
23. Kario K, Sakata T, Matsuo T, Miyata T. Factor VII in non-insulin-dependent diabetic patients with microalbuminuria. Lancet. 1993; 342:1552. Letter.
24. Kario K, Matsuo T, Kobayashi H, Matsuo M, Sakata T, Miyata T. Activation of tissue factor-induced coagulation and endothelial cell dysfunction of non-insulin-dependent diabetic patients with microalbuminuria. Arterioscler Thromb Vase Biol. 1995;15:1114-1120.
25. Sadler EJ. von Willebrand factor. J Biol Chem. 1991;266: 22777-22780.
26. Ishii H, Nakano M, Tsubouchi J, Ishikawa T, Uchiyama H, Hiraishi S, Tahara C, Miyajima Y, Kazama M. Establishment of enzyme immunoassay of human thrombomodulin in plasma and urine using monoclonal antibodies. Thromb Haemost. 1990;63:157-162.
27. Stehouwer CDA, Nauta JJP, Zeldenrust GC, Hackeng WHL, Donker AJM, den Ottolander GJH. Urinary albumin excretion, cardiovascular disease, and endothelial dysfunction in non-insulin-dependent diabetes mellitus. Lancet. 1992;340:319-323.
28. Blann AD, Naqvi T, Waite M, McCollum CN. von Willebrand factor and endothelial damage in essential hypertension. J Hum Hypertens. 1993;7:107-111.
29. Iwashima Y, Sato T, Watanabe K, Ooshima E, Hiraishi S, Ishii H, Kazama M, Makino I. Elevation of plasma thrombomodulin level in diabetic patients with early diabetic nephropathy. Diabetes. 1990;39: 983-988.
30. Ishii H, Uchiyama H, Kazama M. Soluble thrombomodulin antigen in conditioned medium is increased by damage of endothelial cells. Thromb Haemost. 1991;65:618-623.
31. Sokolow M, Werdegar D, Kain HK, Hinman AT. Relationship between level of blood pressure measured casually and by portable recorders and severity of complications in essential hypertension. Circulation. 1966;34:279-298.
32. White WB, Lund-Johansen P, McCabe EJ. Clinical evaluation of the Colin ABPM 630 at rest and during exercise: an ambulatory blood pressure monitor with gas-powered cuff inflation. J Hypertens. 1989;7:477-483.
33. Pickering TG, Harshfield GA, Devereux RB, Laragh JH. What is the role of ambulatory blood pressure monitoring in the management of hypertensive patients? Hypertension. 1985;7:171-177.
34. Shigematsu Y, Miyata T, Higashi S, Miki T, Sadler JE, Iwanaga S. Expression of human soluble tissue factor in yeast and enzymatic properties of its complex with factor Vila. J Biol Chem. 1992;267: 21329-21337.
35. Verdecchia P, Porceilati C, Schiliaci G, Borgioni C, Ciucci A, Battistelli M, Guerrieri M, Gatteschi C, Zampi I, Santucci A, Santucci C, Reboldi G. Ambulatory blood pressure: an independent predictor of prognosis in essential hypertension. Hypertension. 1994;24:793-801,
36. Kario K, Matsuo T, Asada R, Sakata T, Kato H, Miyata T. The strong positive correlation between factor VII clotting activity using bovine thromboplastin and the activated factor VII level. Thromb Haemost. 1995;73:429-434.
37. Kario K, Matsuo T, Matsuo M, Koide M, Yamada T, Nakamura S, Sakata T, Kato H, Miyata T. Marked increase of activated factor VII in uremie patients. Thromb Haemost. 1995;73:763-767.