Use of a quantitative cytomegalovirus (CMV) antigenemia test in evaluating HIV+ patients with and without CMV disease

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Volumn 12, Issue 1, 1996, Pages 33-37

  Wetherill, Patricia E ^a   Landry, Marie L ^a   Alcabes, Philip ^a   Friedland, Gerald ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CMV antigenemia; CMV viremia; HIV infection; Human cytomegalovirus (CMV); Immunocompromise

Indexed keywords

ANTIGEN DETECTION; ARTICLE; CLINICAL ARTICLE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC VALUE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; PRIORITY JOURNAL; VIRUS DETECTION;

CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 5; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0029927913     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199605010-00005     Document Type: Article

References (19)

1. Drew WL. Cytomegalovirus infection in patients with AIDS. Clin Infect Dis 1992;14:608-15.
2. Pertel P, Hirschtick R, Phari J, Chmiel J, Poggensee L, Murphy R. Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus. J Acquir Immune Defic Syndr 1992;5:1069-74.
3. Mazzulli T, Rubin RH, Ferraro MJ, et al. Cytomegalovirus antigenemia: clinical correlation's in transplant recipients and in persons with AIDS. J Clin Microbiol 1993;31:2824-7.
4. Landry ML, Ferguson D. Comparison of quantitative cytomegalovirus antigenemia assay with culture methods and correlation with clinical disease. J Clin Microbiol 1993;31:2851-6.
5. Sprenger HG, Weits J van der Bij, Torensma R, Schirm J, The TH. Detection of cytomegalovirus immediate early antigens in blood leucocytes as a marker for activity of cytomegalovirus infections in AIDS patients. In: Proceedings of the Third International Conference on AIDS. Washington, DC: U.S. Department of Health and Human Services and World Health Organization, 1987.
6. Sprenger HG, Weits J, Anema JT, van der Bij W, Schirm J, The TH. Significance of direct cytomegalovirus (CMV)- immediate early antigens (IEA) detection in blood leucocytes during febrile conditions in AIDS patients. In: Proceedings of the Fourth International Conference on AIDS. Stockholm: Stockholm International Affairs, 1988.
7. Sprenger HG, Weits J, van der Giessen M, Steunbrink G, Schirm J, The TH. Diagnosis or exclusion of systemic cytomegalovirus (CMV) disease in AIDS patients during febrile episodes by the level of the CMV antigenemia test. In: Proceedings of the Seventh International Conference on AIDS. Florence: Istituto Superiore di Sanita, 1991.
8. Bek B, Lepenies J, Bieniek K, et al. High sensitivity of cytomegalovirus (CMV) antigenemia assay for diagnosis and follow-up of CMV disease In AIDS patients. Presented at the International Conference of Antimicrobials and Chemotherapeutics, Orlando, Florida 1994.
9. Gerna G, Parea M, Percivalle E, et al. Human cytomegalovirus viraemia in HIV-1-seropositive patients at various clinical stages of infection. AIDS 1990;40:1027-31.
10. The TH, van der Bij W, van den Berg APM, et al. Cytomegalovirus antigenemia. Rev Infect Dis 1990;12:737-44.
11. Gerna G, Revello MG,Percivalle E, Morini F. Comparison of different immunostaining techniques and monoclonal antibodies to the lower matrix phosphoprotein (pp65) for optimal quantitation of human cytomegalovirus antigenemia. J Clin Microbiol 1992;30:1232-7.
12. van der Bij W, Schirm J, Torensma R, van Son WJ, Tegzess AM, The TH. Comparison between viremia and antigenemia for the detection of cytomegalovirus in blood. J Clin Microbiol 1988;26:2531-5.
13. Gerna G, Zipeta D, Parea M, et al. Monitoring of human cytomegalovirus infections and ganciclovir treatment in heart transplant recipients by determination of viremia, antigenemia, and DNAemia. J Infect Dis 1991;64:488-98.
14. van der Bij W, van Son WJ, van der Berg APM, Tegzess AM, Torensma R, The TH. Cytomegalovirus antigenemia: rapid diagnosis and relationship with CMV-associated clinical syndromes in renal allograft recipients. Transplant Proc 1989;21:2061-4.
15. van den Berg AP, van der Bij W, van Son WJ, et al. Cytomegalovirus antigenemia as a useful marker of symptomatic cytomegalovirus infection after renal transplantation-a report of 130 consecutive patients. Transplantation 1989;48:991-5.
16. van den Berg AP, Klompmaker J, Haagsma EB, et al. Antigenemia in the diagnosis and monitoring of active cytomegalovirus infection after liver transplantation. J Infect Dis 199;164:265-70.
17. Landry ML, Ferguson D, Cohen S, Huber K, Wetherill P. Effect of delayed specimen processing on cytomegalovirus antigenemia test results. J Clin Microbiol 1995;33:257-9.
18. Boeckh M, Woogerd PM, Stevens-Ayers T, Ray CG, Bowden RA. Factors influencing detection of quantitative cytomegalovirus antigenemia. J Clin Microbiol 1994;32:832-4.
19. Erice A, Holm MA, Gill PC, et al. Cytomegalovirus antigenemia assay is more sensitive than the shell vial in cultures for rapid detection of CMV in polymorphonuclear blood leukocytes. J Clin Microbiol 1992;30:2822-5.