Stereoselective interaction of uncharged esters at four muscarinic receptor subtypes

European Journal of Pharmacology

Volumn 303, Issue 3, 1996, Pages 221-226

  Waelbroeck, Magali ^a   Hou, Xue ^a   Wehrle, Jahn ^b   Mutschler, Ernst ^b   Van Tilburg, Erica ^c   Menge, Wiro ^c   Timmerman, Hendrik ^c   Lambrecht, Günter ^b  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b GOETHE UNIVERSITY   (Germany)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

BS 6181; BS 7826, (R) and (S) enantiomer; Carbon analog, uncharged; Muscarinic receptor antagonist; Muscarinic receptor subtype; Stereoselectivity, at muscarinic receptor

Indexed keywords

3,3 DIMETHYLBUTANOL BENZILATE; 3,3 DIMETHYLBUTYL BENZILATE; 4 (4 FLUOROPHENYLCARBAMOYL OXY) 2 BUTYNYL N METHYL PYRROLIDINIUM TOSYLATE; 4 CHLORO MCN A 343; ARECAIDINE PROPARGYL ESTER; BS 7826; CYCLOHEXYL DERIVATIVE; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENANTIOMER; GUINEA PIG; HEART LEFT ATRIUM; ILEUM; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; STEREOSPECIFICITY; VAS DEFERENS;

ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTERS; GUINEA PIGS; MALE; MUSCARINIC ANTAGONISTS; RABBITS; RATS; RECEPTORS, MUSCARINIC; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029927204     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00038-6     Document Type: Article

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