Identification of HLA-DR9 (DRB1*0901)-binding peptide motifs using a phage fUSE5 random peptide library

Human Immunology

Volumn 45, Issue 2, 1996, Pages 131-136

  Fujisao, Shoji ^a   Matsushita, Sho ^a   Nishi, Tohru ^b   Nishimura, Yasuharu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; BINDING PROTEIN; HLA DR3 ANTIGEN;

AMINO ACID SUBSTITUTION; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; BINDING AFFINITY; DISEASE ASSOCIATION; IMMUNE RESPONSE; MYASTHENIA GRAVIS; PRIORITY JOURNAL; RECEPTOR BINDING; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0029926734     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/0198-8859(95)00169-7     Document Type: Article

References (18)

1. Matsuki K, Juji T, Tokunaga K, Takamizawa M, Maeda H, Soda M, Nomura Y, Segawa M: HLA antigens in Japanese patients with myasthenia gravis. J Clin Invest 86:392, 1990.
2. Panina-Bordignon P, Tan A, Termijtelen A, Demotz S, Corradin G, Lanzavecchia A: Universally immunogenic T cell epitopes: promiscuous recognition by T cells. Eur J Immunol 19:2237, 1989.
3. Matsushita S, Takahashi K, Motoki M, Komoriya K, Ikagawa S, Nishimura Y: Allele specificity of structural requirement for peptides bound to HLA-DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome. J Exp Med 180:873, 1994.
4. Scott JK, Smith GP: Searching for peptide ligands with an epitope library. Science 249:386, 1990.
5. Buus S, Sette A, Colón SM, Jenis DM, Grey HM: Isolation and characterization of antigen-Ia complexes involved in T cell recognition. Cell 47:1071, 1986.
6. Koide Y, Awashima F, Yoshida TO, Takenouchi T, Wakisaka A, Moriuchi J, Aizawa M: The role of three distinct Ia-like antigen molecules in human T cell proliferative responses: effect of monoclonal anti-Ia-like antibodies. J Immunol 129:1061, 1982.
7. Hirayama K, Nishimura Y, Tsukamoto K, Sasazuki T: Functional and molecular analysis of three distinct HLA-DR4 β-chains responsible for the MLR between HLA-Dw4, Dw15, and DKT2. J Immunol 137:924, 1986.
8. O'Sullivan D, Sidney J, Appella E, Walker L, Phillips L, Colón SM, Miles C, Chesnut RW, Sette, A: Characterization of the specificity of peptide binding to four DR haplotypes. J Immunol 145:1799, 1990.
9. Stern LJ, Brown JH, Jardetzky TS, Gorga JC, Urban RG, Strominger JL, Wiley DC: Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368:215, 1994.
10. Hammer J, Valsasnini P, Tolba K, Bolin D, Higelin J, Takacs B, Sinigaglia F: Promiscuous and allele-specific anchors in HLA-DR-binding peptides. Cell 74:197, 1993.
11. O'Sullivan D, Arrhenius T, Sidney J, del Guercio M-F, Albertson M, Wall M, Oseroff C, Southwood S, Colón SM, Gaeta FCA, Sette A: On the interaction of promiscuous antigenic peptides with different DR allele: identification of common structural motifs. J Immunol 147: 2663, 1991.
12. Demotz S, Barbey C, Corradin G, Amoroso A, Lanzavecchia A: The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86. Eur J Immunol 23:425, 1993.
13. Krieger JI, Karr RW, Grey HM, Yu W-Y, O'Sullivan D, Batovsky L, Zheng Z-L, Colón SM, Gaeta FCA, Sidney J, Albertson M, del Guercio M-F, Chesnut RW, Sette A: Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition. J Immunol 146:2331, 1991.
14. Sidney J, Oseroff C, Southwood S, Wall M, Ishioka G, Koning F, Sette A: DRB1*0301 molecules recognize structural motif distinct from the one recognized by most DRB1 alleles. J Immunol 149:2634, 1992.
15. Hammer J, Bono E, Gallazzi F, Belunis C, Nagy Z, Sinigaglia F: Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning. J Exp Med 180:2353, 1994.
16. Boehncke W-H, Takeshita T, Pendleton CD, Houghten RA, Sadegh-Nasseri S, Racioppi L, Berzofsky JA, Germain RN: The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition. J Immunol 150: 331, 1993.
17. Moiola L, Protti MP, Manfredi AA, Yuen M-H, Howard Jr JF, Coti-Tronconi BM: T-helper epitopes on human nicotinic acetylcholine receptor in myasthenia gravis. Ann NY Acad Sci 681:198, 1993.
18. 2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sci USA 87:4120, 1990.