-
2
-
-
0026645504
-
Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes
-
Ucker, D. S., P. S. Obermiller, W. Eckhart, J. Apgar, N. Berger, and J. Meyers. Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes. Mol. Cell. Biol. 12:3060-3069 (1992).
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 3060-3069
-
-
Ucker, D.S.1
Obermiller, P.S.2
Eckhart, W.3
Apgar, J.4
Berger, N.5
Meyers, J.6
-
3
-
-
0027217084
-
Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kbp fragments before or in the absence of internucleosomal fragmentation
-
Oberhammer, P., J. W. Wilson, C. Dive, I. D. Morris, J. A. Hickman, A. E. Wakeling, R. P. Walker, and M. Sikorska. Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kbp fragments before or in the absence of internucleosomal fragmentation. EMBO J. 12:3679-3684 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 3679-3684
-
-
Oberhammer, P.1
Wilson, J.W.2
Dive, C.3
Morris, I.D.4
Hickman, J.A.5
Wakeling, A.E.6
Walker, R.P.7
Sikorska, M.8
-
4
-
-
0027412343
-
Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease
-
Oberhammer, F., G. Fritsch, M. Schmied, M. Pavelka, D. Printz, T. Purchio, H. Lassmann, and R. Schulte-Herman. Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease. J. Cell Sci. 104:317-326 (1993).
-
(1993)
J. Cell Sci.
, vol.104
, pp. 317-326
-
-
Oberhammer, F.1
Fritsch, G.2
Schmied, M.3
Pavelka, M.4
Printz, D.5
Purchio, T.6
Lassmann, H.7
Schulte-Herman, R.8
-
5
-
-
0029074102
-
Investigation of the mechanism of higher order chromatin fragmentation observed in drug-induced apoptosis
-
Beere, H. M., C. M Chresta, A. Alejo-Herberg, A Skladanowski, C. Dive, A. Kragh-Larsen, and J. A. Hickman. Investigation of the mechanism of higher order chromatin fragmentation observed in drug-induced apoptosis. Mol. Pharmacol. 47:986-996 (1995).
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 986-996
-
-
Beere, H.M.1
Chresta, C.M.2
Alejo-Herberg, A.3
Skladanowski, A.4
Dive, C.5
Kragh-Larsen, A.6
Hickman, J.A.7
-
6
-
-
0027479655
-
Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments before internucleosomal fragmentation
-
Brown, D. G., X. M. Sun, and G. M. Cohen. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments before internucleosomal fragmentation. J Biol Chem. 268:3037-3039 (1993).
-
(1993)
J Biol Chem.
, vol.268
, pp. 3037-3039
-
-
Brown, D.G.1
Sun, X.M.2
Cohen, G.M.3
-
7
-
-
0028038964
-
Changes m nuclear chromatin precede internucleosomal DNA cleavage in the induction of apoptosis by etoposide
-
Sun, X. M , R. Snowden, D. Dinsdale, M. Ormerod, and G. M. Cohen. Changes m nuclear chromatin precede internucleosomal DNA cleavage in the induction of apoptosis by etoposide. Biochem. Pharmacol. 2:187-195 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.2
, pp. 187-195
-
-
Sun, X.M.1
Snowden, R.2
Dinsdale, D.3
Ormerod, M.4
Cohen, G.M.5
-
8
-
-
0026788002
-
Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation
-
Cohen, G. M, X. M. Sun, R. T. Snowden, D. Dinsdale, and D. N. Skilleter. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem. J. 286:331-334 (1992).
-
(1992)
Biochem. J.
, vol.286
, pp. 331-334
-
-
Cohen, G.M.1
Sun, X.M.2
Snowden, R.T.3
Dinsdale, D.4
Skilleter, D.N.5
-
9
-
-
0025890303
-
Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes
-
Walker, P. R , C. Smith, T. Youdale, J. Leblanc, J. F. Whitfield, and M. Sikorska. Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes. Cancer Res. 51:1078-1085 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 1078-1085
-
-
Walker, P.R.1
Smith, C.2
Youdale, T.3
Leblanc, J.4
Whitfield, J.F.5
Sikorska, M.6
-
10
-
-
0026720052
-
The topoisomerase II inhibitor teniposide (VM-26) induces apoptosis in unstimulated murine lymphocytes
-
Roy, C., D. L. Brown, J. E. Little, B. K. Valentine, P. R. Walker, M. Sikorska, J. Leblanc, and N. Chaly. The topoisomerase II inhibitor teniposide (VM-26) induces apoptosis in unstimulated murine lymphocytes. Exp. Cell. Res. 200:416-424 (1992).
-
(1992)
Exp. Cell. Res.
, vol.200
, pp. 416-424
-
-
Roy, C.1
Brown, D.L.2
Little, J.E.3
Valentine, B.K.4
Walker, P.R.5
Sikorska, M.6
Leblanc, J.7
Chaly, N.8
-
11
-
-
0023225704
-
Recent studies of DNA topoisomerases
-
Wang, J. C Recent studies of DNA topoisomerases. Biochem. Biophys. Acta 909:1-9 (1987).
-
(1987)
Biochem. Biophys. Acta
, vol.909
, pp. 1-9
-
-
Wang, J.C.1
-
12
-
-
0040860278
-
In situ localization of DNA topoisomerase II, a major polypeptide component of the drosophila nuclear matrix fraction
-
Berrios, M., N. Osheroff, and P. A. Fisher. In situ localization of DNA topoisomerase II, a major polypeptide component of the drosophila nuclear matrix fraction. Proc. Natl. Acad. Sci. USA 82:4142-4146 (1985).
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 4142-4146
-
-
Berrios, M.1
Osheroff, N.2
Fisher, P.A.3
-
13
-
-
0021966486
-
Localization of topoisomerase II in mitotic chromosomes
-
Earnshaw, W. C., and M. S. Heck. Localization of topoisomerase II in mitotic chromosomes. J. Cell Biol. 100:1716-1725 (1985).
-
(1985)
J. Cell Biol.
, vol.100
, pp. 1716-1725
-
-
Earnshaw, W.C.1
Heck, M.S.2
-
14
-
-
0021958085
-
Topoisomerase II is a structural component of mitotic chromosome scaffolds
-
Earnshaw, W. C., B. Halligan, C. A. Cooke, M. S. Heck, and L. F. Liu. Topoisomerase II is a structural component of mitotic chromosome scaffolds. J. Cell Biol. 100:1706-1715 (1986).
-
(1986)
J. Cell Biol.
, vol.100
, pp. 1706-1715
-
-
Earnshaw, W.C.1
Halligan, B.2
Cooke, C.A.3
Heck, M.S.4
Liu, L.F.5
-
15
-
-
0024826968
-
Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions
-
Adaehi, Y., E. Kas, and U. K. Laemmli. Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions. EMBO J. 8:3997-4006 (1990).
-
(1990)
EMBO J.
, vol.8
, pp. 3997-4006
-
-
Adaehi, Y.1
Kas, E.2
Laemmli, U.K.3
-
16
-
-
0022553738
-
Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer region containing topoisomerase II sites
-
Cockerill, P. N., and W. T. Garrard. Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer region containing topoisomerase II sites. Cell 44:273-282 (1986).
-
(1986)
Cell
, vol.44
, pp. 273-282
-
-
Cockerill, P.N.1
Garrard, W.T.2
-
17
-
-
0000506532
-
The organization of the higher-order chromatin loop: Specific DNA attachment sites on nuclear scaffold
-
Gasser, S. M., and U. K. Laemmli. The organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold. EMBO J. 5:511-518 (1986).
-
(1986)
EMBO J.
, vol.5
, pp. 511-518
-
-
Gasser, S.M.1
Laemmli, U.K.2
-
18
-
-
0025317569
-
Periodicity of DNA folding in higher order chromatin structures
-
Filipski, J., J. Leblanc, T. Youdale, M. Sikorska, and P. R. Walker. Periodicity of DNA folding in higher order chromatin structures. EMBO J. 9:1319-1327 (1990).
-
(1990)
EMBO J.
, vol.9
, pp. 1319-1327
-
-
Filipski, J.1
Leblanc, J.2
Youdale, T.3
Sikorska, M.4
Walker, P.R.5
-
19
-
-
0021749639
-
Nonintercalative antitumour drugs interfere with the breakage-reunion of topoisomerase II
-
Chen, G. L., L. Yang, T. C. Rowe, B. D. Halligan, K M. Tewey, and L. F. Liu. Nonintercalative antitumour drugs interfere with the breakage-reunion of topoisomerase II. J. Biol. Chem. 259:13560-13566 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 13560-13566
-
-
Chen, G.L.1
Yang, L.2
Rowe, T.C.3
Halligan, B.D.4
Tewey, K.M.5
Liu, L.F.6
-
20
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu, L. F. DNA topoisomerase poisons as antitumor drugs. Annu Rev. Biochem. 58:351-375 (1989).
-
(1989)
Annu Rev. Biochem.
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
21
-
-
0020334850
-
Biological properties of ICRF-159 and other related bis(dioxopiperazine) derivatives
-
Herman, E. H., D. T. Witiak, K. Hellmann, and V. S. Waravdeker. Biological properties of ICRF-159 and other related bis(dioxopiperazine) derivatives. Adv. Pharmacol. Chemother. 19:249-290 (1982).
-
(1982)
Adv. Pharmacol. Chemother.
, vol.19
, pp. 249-290
-
-
Herman, E.H.1
Witiak, D.T.2
Hellmann, K.3
Waravdeker, V.S.4
-
22
-
-
0026425619
-
Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives
-
Tanabe, K., Y. Ikegami, R. Ishida, and T. Andoh. Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives. Cancer Res. 51:4903-4908 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 4903-4908
-
-
Tanabe, K.1
Ikegami, Y.2
Ishida, R.3
Andoh, T.4
-
23
-
-
0027214092
-
Antagonistic effect of the cardioprotector (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase H directed drugs daunorubicin and etoposide (VP-16)
-
Sehested, M., P. Buhl, B. S. Sorenson, B. Holm, E. Friche, and E. J. F. Demant. Antagonistic effect of the cardioprotector (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase H directed drugs daunorubicin and etoposide (VP-16). Biochem. Pharmacol. 46:389-393 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 389-393
-
-
Sehested, M.1
Buhl, P.2
Sorenson, B.S.3
Holm, B.4
Friche, E.5
Demant, E.J.F.6
-
24
-
-
0027142604
-
Changes in HSC70 and C-myc in HL-60 cells engaging differentiation or apoptosis
-
Beere, H. M., J. A. Hickman, R. I. Morimoto, R. Parmar, R. Newbould., and C. M. Waters. Changes in HSC70 and C-myc in HL-60 cells engaging differentiation or apoptosis. Mol. Cell. Diff. 1:323-343 (1993).
-
(1993)
Mol. Cell. Diff.
, vol.1
, pp. 323-343
-
-
Beere, H.M.1
Hickman, J.A.2
Morimoto, R.I.3
Parmar, R.4
Newbould, R.5
Waters, C.M.6
-
25
-
-
0017782474
-
Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture
-
Collins, S. J., R. C. Gallo, and R. E. Gallagher. Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature (Lond.) 270:347-349 (1977).
-
(1977)
Nature (Lond.)
, vol.270
, pp. 347-349
-
-
Collins, S.J.1
Gallo, R.C.2
Gallagher, R.E.3
-
26
-
-
0024372723
-
Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes
-
Chung, T. D., F. H. Drake, K. B. Tan, S. R. Per, S. T. Crooke, and C. K. Mirabelli. Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes. Proc. Natl. Acad. Sci. USA 86:9431-9435.
-
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 9431-9435
-
-
Chung, T.D.1
Drake, F.H.2
Tan, K.B.3
Per, S.R.4
Crooke, S.T.5
Mirabelli, C.K.6
-
27
-
-
0026441120
-
Isolation of cDNA clones encoding the beta-isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24
-
Jenkins, J. R., P. Ayton, T. Jones, S. L. Davies, D. L. Simmons, A. L. Harris, D. Sheer, and I. D. Hickson. Isolation of cDNA clones encoding the beta-isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24. Nucleic Acids Res. 20:5587-5592 (1992).
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5587-5592
-
-
Jenkins, J.R.1
Ayton, P.2
Jones, T.3
Davies, S.L.4
Simmons, D.L.5
Harris, A.L.6
Sheer, D.7
Hickson, I.D.8
-
28
-
-
0017186787
-
Fractionation of DNA from mammalian cells by alkaline elution
-
Kohn, K. W., L. C. Ericson, R. Ewig, and C. A. Friedman. Fractionation of DNA from mammalian cells by alkaline elution. Biochemistry 15:4629-4637 (1976).
-
(1976)
Biochemistry
, vol.15
, pp. 4629-4637
-
-
Kohn, K.W.1
Ericson, L.C.2
Ewig, R.3
Friedman, C.A.4
-
29
-
-
0026543962
-
Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry
-
Dive, C., C. D. Gregory, D. J. Phipps, D. L. Evans, A. E. Milner, and A. H. Wyllie. Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry. Biochim. Biophys. Acte 1133:275-285 (1991).
-
(1991)
Biochim. Biophys. Acte
, vol.1133
, pp. 275-285
-
-
Dive, C.1
Gregory, C.D.2
Phipps, D.J.3
Evans, D.L.4
Milner, A.E.5
Wyllie, A.H.6
-
30
-
-
0029042718
-
Nuclear changes in apoptosis
-
Earnshaw, W. C. Nuclear changes in apoptosis. Curr. Opin. Cell Biol. 7:337-343 (1995).
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 337-343
-
-
Earnshaw, W.C.1
-
31
-
-
0026425654
-
Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: Mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors
-
Ishida, R., T. Miki, T. Narita, R. Yui, M. Sato, K. R. Utsumi, K. Tanabe, and T. Andoh. Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors. Cancer Res. 51:4909-4916 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 4909-4916
-
-
Ishida, R.1
Miki, T.2
Narita, T.3
Yui, R.4
Sato, M.5
Utsumi, K.R.6
Tanabe, K.7
Andoh, T.8
-
32
-
-
0027255417
-
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann, S. H., S. Y. Desnoyers, Y. Ottaviano, N. E. Davidson, and G. Poirier. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res. 53:3976-3985 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.Y.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.5
-
33
-
-
9344267865
-
Activation of cdc2 precedes lamin breakdown during apoptosis allowing DNase I to enter the nucleus and leading to DNA breakdown
-
European Network of Immunology Institutes (ENII), Les Embiez, France
-
Schroter, M., M. Peitsch, P. Gallant, E. A. Nigg, and J. Tschopp. Activation of cdc2 precedes lamin breakdown during apoptosis allowing DNase I to enter the nucleus and leading to DNA breakdown, in Molecular Basis of Immunology. European Network of Immunology Institutes (ENII), Les Embiez, France, (1994).
-
(1994)
Molecular Basis of Immunology
-
-
Schroter, M.1
Peitsch, M.2
Gallant, P.3
Nigg, E.A.4
Tschopp, J.5
-
34
-
-
0027458695
-
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death)
-
Peitsch, M. C., B. Polzar, H. Stephan, T. Crompton, H. R. MacDonald, H. G. Mannherz, and J. Tschopp. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J. 12:371-377 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 371-377
-
-
Peitsch, M.C.1
Polzar, B.2
Stephan, H.3
Crompton, T.4
MacDonald, H.R.5
Mannherz, H.G.6
Tschopp, J.7
-
35
-
-
0028878468
-
A pre-existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli
-
Fearnhead, H. O., J. A. Rivett, D. Dinsdale, and G. M. Cohen. A pre-existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli. FEBS Lett. 357:242-246 (1995).
-
(1995)
FEBS Lett.
, vol.357
, pp. 242-246
-
-
Fearnhead, H.O.1
Rivett, J.A.2
Dinsdale, D.3
Cohen, G.M.4
-
37
-
-
0027658225
-
Role of proteolysis in apoptosis: Involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes
-
Weaver, V. M., B. Lach P. R. Walker, and M. Sikorska. Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes. Biochem. Cell. Biol. 71:488-500 (1993).
-
(1993)
Biochem. Cell. Biol.
, vol.71
, pp. 488-500
-
-
Weaver, V.M.1
Lach, B.2
Walker, P.R.3
Sikorska, M.4
|