Potent inhibition of the inducible isoform of nitric oxide synthase by aminoethylisoselenourea and related compounds

Life Sciences

Volumn 58, Issue 14, 1996, Pages 1139-1148

  Southan, Garry J ^a   Salzman, Andrew L ^a   Szabó, Csaba ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Aminoalkylselenoureas; Blood pressure; Nitric oxide synthase inhibitor; Selenoalkylguanidines

Indexed keywords

AMINOETHYLISOSELENOUREA; AMINOETHYLISOTHIOURONIUM; AMINOPROPYLISOSELENOUREA; ARGININE; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; HEMODYNAMICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRESSOR RESPONSE; RAT;

EID: 0029926451     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(96)00072-0     Document Type: Article

References (30)

1. C. NATHAN, FASEB J. 6 3051-3064 (1992).
2. M.A. MARLETTA, J. Biol. Chem. 268 12231-12234 (1993).
3. Q. XIE and C. NATHAN, J. Leukoc. Biol. 56 576-582 (1994).
4. C. SZABÓ, New Horizons 3 2-32 (1995).
5. J.R. VANE, Proc. Roy. Soc. Lond. B 343 225-246 (1994).
6. J.L. DINERMAN, C.J. LOWENSTEIN and S.H. SNYDER, Circ. Res. 73 217-222 (1993).
7. S.H. SNYDER and D.S. BREDT, Scientific American 166 28-35 (1992).
8. V.M. DAWSON, T.M. DAWSON, E.D. LONDON, D.S. BREDT and S.H. SNYDER, Proc. Natl. Acad. Sci. U.S.A. 88 6368-6371 (1991).
9. J. GARTHWAITE, T.I.N.S. 14 60-67 (1991).
10. S.S. GROSS, E.A. JAFFE, R. LEVI and R.G. KILBOURN, Biochem. Biophys. Res. Comm. 187 823-829 (1991).
11. L. E. LAMBERT, J.P. WHITTEN, B.M. BARON, H.C. CHENG, N.S. DOHERTY and I.A. McDONALD, Life Sci. 48 69-75 (1991).
12. T.P. MISKO, W.M. MOORE, T.P. KASTEN, D.A. NICKOLS, J.A. CORBETT, R.G. TILTON, M.L. McDANIEL, J.R. WILLIAMSON and M.G. CURRIE, Eur. J. Pharmacol. 233 119-125 (1993).
13. E.P. GARVEY, J.A. OPLINGER, G.J. TANOURY, P.A. SHERMAN, M. FOWLER, S. MARSHALL, M.F. HARMON, J.E. PAITH and E.S. FURFINE, J. Biol. Chem. 269 26669-26676 (1994).
14. G.J. SOUTHAN, C. SZABÓ and C. THIEMERMANN, Br. J. Pharmacol. 114 510-516 (1995).
15. M. NAKANE, V. KLINGHOFER, J.E. KUK, J.L. DONNELLY, G.P. BUDZIK, J.S. POLLOCK, F. BASHA and G.W. CARTER Mol. Pharmacol. 47 831-834 (1995).
16. A.H. CROSS, T.P. MISKO, R.F. LIN, W.F. HICKEY, J.L. TROTTER and R.G. TILTON, J. Clin. Invest. 93 2684-90 (1994).
17. C. SZABÓ, G.J. SOUTHAN and C. THIEMERMANN, Proc. Natl. Acad. Sci. U.S.A. 91 12472-12476 (1994).
18. C.C. WU, S.J. CHEN, C. SZABÓ and C. THIEMERMANN, and J.R. VANE, Br. J. Pharmacol. 114 1666-1672 (1995).
19. N. WORRALL, W. LAZENBY, T. MISKO, T. LIN, C. RODI, P. MANNING, R. TILTON, J. WILLIAMSON and T.J. FERGUSON, JR. J. Exp. Med. 181 63-70 (1995).
20. S.H. CHU and H.G. MAUTNER, J. Am. Chem. Soc. 27 2899-2901 (1962).
21. D.R. GRASETTI and J.F. MURRAY, Arch. Biochem. Biophys. 119 41-49 (1967).
22. C. SZABÓ, G.J. SOUTHAN and C. THIEMERMANN, and J.R. VANE, Br. J. Pharmacol. 113 757-766 (1994).
23. R.G. BOGLE, S. MONCADA, J.D. PEARSON and G.E. MANN, Br. J. Pharmacol. 105 768-770 (1992).
24. D.G. DOHERTY, R. SHAPIRA and W.T. BURNETT, J. Am. Chem. Soc. 79 5667-5671 (1957).
25. J.X. KHYM, R. SHAPIRA and D.G. DOHERTY J. Am. Chem. Soc. 79 5663-5666 (1957).
26. G.J. SOUTHAN, A.L. SALZMAN and C. SZABÓ, FASEB J. 8 A28 (1995).
27. F.N. FASTIER and F. SMIRK, J. Pharmacol. 89 256-270 (1947).
28. S.M. KORB, G. ALBORNOZ and J.A, LIGHT, Transplant. Proc. 22 452-4 (1990).
29. K.E. BURKE, G.F. COMBS JR., K.C. BHUYAN and H. ABU-LIBDEH, Nutr. Cancer 17 123-37 (1992).
30. P. BAUER, F. BELLEVILLE-NABET, F. DUBOIS and A. LARCAN, Ann. New York Acad. Sci. 723 433-5 (1995)