Increased extracellular matrix synthesis by smooth-muscle cells obtained from in vivo restenotic lesions by directional coronary atherectomy

American Heart Journal

Volumn 131, Issue 3, 1996, Pages 613-615

  Violaris, Andonis G ^a   De Jong, Marcel ^b   MacLeod, Donald C ^a   Umans, Victor A ^a   Verdouw, Pieter D ^b   Serruys, Patrick W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; PROLINE;

ANGIOGRAPHY; ARTICLE; ATHERECTOMY; COLLAGEN SYNTHESIS; CORONARY ARTERY DILATATION; ELECTRON MICROSCOPY; EXTRACELLULAR MATRIX; HUMAN; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MITRAL VALVE STENOSIS; PHENOTYPE; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER;

EID: 0029926443     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-8703(96)90548-7     Document Type: Article

References (6)

1. MacLeod DC, Strauss BH, de Jong M, Umans VA, Escaned J, van Suylen RJ, Verkerk A, de Feyter PJ, Serruys PW. Proliferation and extracellular matrix synthesis of smooth muscle cells cultured from human coronary atherosclerotic and restenotic lesions. J Am Coll Cardiol 1994;23:59-65.
2. Merrilees MJ. Synthesis of glycosaminoglycans and proteoglycans. In: Campbell JH, Campbell GR, eds. Vascular smooth muscle cell in culture. Vol 1. Boca Raton, Fla.: CRC Press Inc., 1987:133-51.
3. Leclerc G, Isner JM, Kearney M, Simons M, Safian RD, Baim DS, Weir L. Evidence implicating nonmuscle myosin in restenosis: use of in situ hybridization to analyze human vascular lesions obtained by directional atherectomy. Circulation 1992;85:543-53.
4. Bauriedel G, Windstetter U, DeMaio SJ Jr, Kandolf R, Hofling B. Migratory activity of human smooth muscle cells cultivated from coronary and peripheral primary and restenotic lesions removed by percutaneous atherectomy. Circulation 1992;85:554-64.
5. Pickering JG, Weir L, Rosenfield K, Stetz J, Jekanowski J, Isner JM. Smooth muscle cell outgrowth from human atherosclerotic plaque: implications for the assessment of lesion biology. J Am Coll Cardiol 1992;20:1430-9.
6. Nikol S, Isner JM, Pickering JG, Kearney M, Leclerc G, Weir L. Expression of transforming growth factor-beta 1 is increased in human vascular restenosis lesions. J Clin Invest 1992;90:1582-92.