-
1
-
-
0342604033
-
The effects of zanoterone, a steroidal androgen receptor antagonist, in men with benign prostatic hyperplasia
-
Berger, B. M., Naadimuthu, A., Boddy, A., Fisher, H. A., McConnell, J. D., Milam, D., Mobley, D., and Rajfer, J. (1995). The effects of zanoterone, a steroidal androgen receptor antagonist, in men with benign prostatic hyperplasia. J. Urol. 194, 150-154.
-
(1995)
J. Urol.
, vol.194
, pp. 150-154
-
-
Berger, B.M.1
Naadimuthu, A.2
Boddy, A.3
Fisher, H.A.4
McConnell, J.D.5
Milam, D.6
Mobley, D.7
Rajfer, J.8
-
2
-
-
0014125542
-
Pharmacological implications of microsomal enzyme induction
-
Conney, A. H. (1967). Pharmacological implications of microsomal enzyme induction. Pharmacol. Rev. 19, 317-366.
-
(1967)
Pharmacol. Rev.
, vol.19
, pp. 317-366
-
-
Conney, A.H.1
-
3
-
-
0011343858
-
Liver function tests in the differential diagnosis of hepatotoxicity
-
(R. G. Meeks, S. D. Harrison, and R. J. Bull, Eds.), CRC Press, Boca Raton, FL
-
Cornelius, C. E. (1991). Liver function tests in the differential diagnosis of hepatotoxicity. In Hepatotoxicology (R. G. Meeks, S. D. Harrison, and R. J. Bull, Eds.), pp. 181-213. CRC Press, Boca Raton, FL.
-
(1991)
Hepatotoxicology
, pp. 181-213
-
-
Cornelius, C.E.1
-
4
-
-
0343909778
-
Evidence of hepatic enzyme induction in rats by zanoterone, a novel steroidal androgen receptor antagonist
-
Descotes, G., Gallas, J. F., Reid, A., Penacchio, E., and Moreau, C. (1993). Evidence of hepatic enzyme induction in rats by zanoterone, a novel steroidal androgen receptor antagonist. Pharmacol. Toxicol. 73(Supp. II), 112.
-
(1993)
Pharmacol. Toxicol.
, vol.73
, Issue.2 SUPPL.
, pp. 112
-
-
Descotes, G.1
Gallas, J.F.2
Reid, A.3
Penacchio, E.4
Moreau, C.5
-
5
-
-
0018750844
-
Choleretic and cholestatic effects of infused bile salts in the rat
-
Drew, R., and Priestly, B. G. (1979). Choleretic and cholestatic effects of infused bile salts in the rat. Experientia 35, 809-811.
-
(1979)
Experientia
, vol.35
, pp. 809-811
-
-
Drew, R.1
Priestly, B.G.2
-
6
-
-
0015874446
-
Neonatal imprinting of liver microsomal hydroxylation and reduction of steroids
-
Einarsson, K., Gustafsson, J. A., and Stenberg, A. (1973). Neonatal imprinting of liver microsomal hydroxylation and reduction of steroids. J. Biol. Chem. 248, 4987-4996.
-
(1973)
J. Biol. Chem.
, vol.248
, pp. 4987-4996
-
-
Einarsson, K.1
Gustafsson, J.A.2
Stenberg, A.3
-
7
-
-
0027477884
-
Formation of N-methyl protoporphyrin in chemically-induced protoporphyria. Studies with a novel porphyrogenic agent
-
Frater, Y., Brady, A., Lock, E. A., and De Matteis, F. (1993). Formation of N-methyl protoporphyrin in chemically-induced protoporphyria. Studies with a novel porphyrogenic agent. Arch. Toxicol. 67, 179-185.
-
(1993)
Arch. Toxicol.
, vol.67
, pp. 179-185
-
-
Frater, Y.1
Brady, A.2
Lock, E.A.3
De Matteis, F.4
-
8
-
-
0018326895
-
Assessment of serum cholesterol by two methods: Gas-liquid chromatography on a capillary column and chemical ionization-mass fragmentography with isotopic dilution of (3,4-13C) cholesterol as internal standard
-
Gambert, C., Lallemant, C., Archambault, A., Maume, B. F., and Padieu, P. (1979). Assessment of serum cholesterol by two methods: Gas-liquid chromatography on a capillary column and chemical ionization-mass fragmentography with isotopic dilution of (3,4-13C) cholesterol as internal standard. J. Chromatogr. Biomed. Appl. 162, 1-6.
-
(1979)
J. Chromatogr. Biomed. Appl.
, vol.162
, pp. 1-6
-
-
Gambert, C.1
Lallemant, C.2
Archambault, A.3
Maume, B.F.4
Padieu, P.5
-
9
-
-
0015121587
-
Studies on the mechanism of the ethynylestradiol impairment of bile flow and bile salt excretion in the rat
-
Gumucio, J. J., and Valdivieso, V. D. (1971). Studies on the mechanism of the ethynylestradiol impairment of bile flow and bile salt excretion in the rat. Gastroenterology 61, 339-344.
-
(1971)
Gastroenterology
, vol.61
, pp. 339-344
-
-
Gumucio, J.J.1
Valdivieso, V.D.2
-
10
-
-
0015950191
-
Irreversible androgenic programming at birth of microsomal and soluble rat liver enzymes active on 4-androstene-3,17-dione and 5α-androstane-3α,17β-diol
-
Gustafsson, J. A., and Stenberg, A. (1974). Irreversible androgenic programming at birth of microsomal and soluble rat liver enzymes active on 4-androstene-3,17-dione and 5α-androstane-3α,17β-diol. J. Biol. Chem. 249, 711-718.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 711-718
-
-
Gustafsson, J.A.1
Stenberg, A.2
-
11
-
-
0014287967
-
Effect of sodium taurolithocholate on bile flow and bile acid excretion
-
Javitt, N. B., and Emerman, S. (1968). Effect of sodium taurolithocholate on bile flow and bile acid excretion. J. Clin. Invest. 47, 1002-1014.
-
(1968)
J. Clin. Invest.
, vol.47
, pp. 1002-1014
-
-
Javitt, N.B.1
Emerman, S.2
-
12
-
-
0025303453
-
The effect of the steroidal androgen receptor antagonist, Win 49,596, on the prostate and testis of beagle dogs
-
Juniewicz, P. E., McCarty, M., Lemp, B. M., Barbolt, T. A., Shaw, C., Hollenbauch, D. M., Winneker, R. C., Reel, J. R., and Batzold, F. H. (1990). The effect of the steroidal androgen receptor antagonist, Win 49,596, on the prostate and testis of beagle dogs. Endocrinology 126, 2625-2634.
-
(1990)
Endocrinology
, vol.126
, pp. 2625-2634
-
-
Juniewicz, P.E.1
McCarty, M.2
Lemp, B.M.3
Barbolt, T.A.4
Shaw, C.5
Hollenbauch, D.M.6
Winneker, R.C.7
Reel, J.R.8
Batzold, F.H.9
-
13
-
-
0025917469
-
Evaluation of WIN 49596, a novel steroidal androgen receptor antagonist, in animal models of prostate cancer
-
Juniewicz, P. E., Fetrow, N., Marinelli, J., Wolf, M., Young, E., Lamb, J., and Isaacs, J. T. (1991). Evaluation of WIN 49596, a novel steroidal androgen receptor antagonist, in animal models of prostate cancer. Prostate 18, 105-115.
-
(1991)
Prostate
, vol.18
, pp. 105-115
-
-
Juniewicz, P.E.1
Fetrow, N.2
Marinelli, J.3
Wolf, M.4
Young, E.5
Lamb, J.6
Isaacs, J.T.7
-
14
-
-
0343038164
-
Pharmacokinetics and metabolism of the androgen receptor antagonist zanoterone in normal human males
-
Kennedy, C. D., Rudewicz, P. J., Xu, Z. X., Newton, J. F., Baker, J. F., Rodger, C. A., Berger, B. M., VonRoemeling, R. W., Stack, R. F., and Johnson, J. A. (1994). Pharmacokinetics and metabolism of the androgen receptor antagonist zanoterone in normal human males. ISSX Proc. 6, 89.
-
(1994)
ISSX Proc.
, vol.6
, pp. 89
-
-
Kennedy, C.D.1
Rudewicz, P.J.2
Xu, Z.X.3
Newton, J.F.4
Baker, J.F.5
Rodger, C.A.6
Berger, B.M.7
VonRoemeling, R.W.8
Stack, R.F.9
Johnson, J.A.10
-
15
-
-
0027340407
-
Temporal relationship of changes in hepatobiliary function and morphology in rats following α-naphthylisothiocyanate (ANIT) administration
-
Kossor, D. C., Meunier, P. C., Handler, J. A., Sozio, R. S., and Goldstein, R. S. (1993). Temporal relationship of changes in hepatobiliary function and morphology in rats following α-naphthylisothiocyanate (ANIT) administration. Toxicol. Appl. Pharmacol. 119, 108-114.
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.119
, pp. 108-114
-
-
Kossor, D.C.1
Meunier, P.C.2
Handler, J.A.3
Sozio, R.S.4
Goldstein, R.S.5
-
16
-
-
0343909776
-
Differences in cholesterol oxidation and biosynthesis in liver of male and female rats
-
Kritchevsky, D., Staple, E., Rabinowitz, J., and Whitehouse, M. W. (1961). Differences in cholesterol oxidation and biosynthesis in liver of male and female rats. Am., J. Physiol. 200, 519-522.
-
(1961)
Am., J. Physiol.
, vol.200
, pp. 519-522
-
-
Kritchevsky, D.1
Staple, E.2
Rabinowitz, J.3
Whitehouse, M.W.4
-
17
-
-
0026597115
-
Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats
-
Gastrointest. Liver Physiol. 25
-
Kuipers, F., Hardonk, M. J., Vonk, R. J., and Van der Meer, R. (1992). Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats. Am. J. Physiol. 262 (Gastrointest. Liver Physiol. 25), G267-G273.
-
(1992)
Am. J. Physiol.
, vol.262
-
-
Kuipers, F.1
Hardonk, M.J.2
Vonk, R.J.3
Van Der Meer, R.4
-
18
-
-
0016268382
-
A light and electron microscopic study of the liver in a case of erythrohepatic protoporphyria and in griseofulvin-induced porphyria in mice
-
Matilla, A., and Molland, E. A. (1974). A light and electron microscopic study of the liver in a case of erythrohepatic protoporphyria and in griseofulvin-induced porphyria in mice. J. Clin. Pathol. 27, 698-709.
-
(1974)
J. Clin. Pathol.
, vol.27
, pp. 698-709
-
-
Matilla, A.1
Molland, E.A.2
-
19
-
-
0019495215
-
Steroid D-ring glucuronides: Characterization of a new class of cholestatic agents in the rat
-
Meyers, M., Slikker, W., and Vore, M. (1981). Steroid D-ring glucuronides: Characterization of a new class of cholestatic agents in the rat. J. Pharmacol. Exp. Ther. 218, 63-73.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.218
, pp. 63-73
-
-
Meyers, M.1
Slikker, W.2
Vore, M.3
-
20
-
-
0017345201
-
Subcellular pathology of rat liver in cholestasis and choleresis induced by bile salts. Effects of lithocholic, 3β-hydroxy-5-cholenoic, cholic and dehydrocholic acids
-
Miyai, K., Richardson, A. L., Mayr, W. W., and Javitt, N. B. (1977). Subcellular pathology of rat liver in cholestasis and choleresis induced by bile salts. Effects of lithocholic, 3β-hydroxy-5-cholenoic, cholic and dehydrocholic acids. Lab. Invest. 36, 249-258.
-
(1977)
Lab. Invest.
, vol.36
, pp. 249-258
-
-
Miyai, K.1
Richardson, A.L.2
Mayr, W.W.3
Javitt, N.B.4
-
21
-
-
0020358475
-
Bromsulphalein (BSP) kinetics in the rat: A new approach in evaluating experimental hepatotoxicity
-
Molino, G., Cavanna, A., Biondi, A. M., Macri, G., Urigu, S., and Ugazio, G. (1982). Bromsulphalein (BSP) kinetics in the rat: A new approach in evaluating experimental hepatotoxicity. Int. Arch. Occup. Environ. Health 51, 73-79.
-
(1982)
Int. Arch. Occup. Environ. Health
, vol.51
, pp. 73-79
-
-
Molino, G.1
Cavanna, A.2
Biondi, A.M.3
Macri, G.4
Urigu, S.5
Ugazio, G.6
-
22
-
-
0017209208
-
Intrahepatic cholestasis induced by drugs and chemicals
-
Plaa, G. L., and Priestly, B. G. (1977). Intrahepatic cholestasis induced by drugs and chemicals. Pharmacol. Rev. 28, 207-273.
-
(1977)
Pharmacol. Rev.
, vol.28
, pp. 207-273
-
-
Plaa, G.L.1
Priestly, B.G.2
-
23
-
-
0015174806
-
Biochemical and morphological parameters of taurolithocholate-induced cholestasis
-
Priestly, B. G., Côté, M. G., and Plaa, G. L. (1971). Biochemical and morphological parameters of taurolithocholate-induced cholestasis. Can. J. Physiol. Pharmacol. 49, 1078-1091.
-
(1971)
Can. J. Physiol. Pharmacol.
, vol.49
, pp. 1078-1091
-
-
Priestly, B.G.1
Côté, M.G.2
Plaa, G.L.3
-
24
-
-
0343474009
-
Effects of zanoterone, a steroidal androgen receptor antagonist, on monooxygenation of testosterone, ethoxycoumarin and ethoxyresorufin and glucuronidation of p-nitrophenol in rats
-
Ritz, M. A., Descotes, G., and Roberts, A. E. (1993). Effects of zanoterone, a steroidal androgen receptor antagonist, on monooxygenation of testosterone, ethoxycoumarin and ethoxyresorufin and glucuronidation of p-nitrophenol in rats. ISSX Proc. 4, 106.
-
(1993)
ISSX Proc.
, vol.4
, pp. 106
-
-
Ritz, M.A.1
Descotes, G.2
Roberts, A.E.3
-
25
-
-
0014088940
-
Maximum biliary excretion of bilirubin and sulfobromophthalein during anesthesia-induced alteration of rectal temperature
-
Roberts, R. J., Klaasen, C. D., and Plaa, G. L. (1967). Maximum biliary excretion of bilirubin and sulfobromophthalein during anesthesia-induced alteration of rectal temperature. Proc. Soc. Exp. Biol. Med. 125, 313-316.
-
(1967)
Proc. Soc. Exp. Biol. Med.
, vol.125
, pp. 313-316
-
-
Roberts, R.J.1
Klaasen, C.D.2
Plaa, G.L.3
-
26
-
-
0001904160
-
Biotransformation of toxicants
-
(M. O. Amdur, J. Doull, and C. D. Klaassen, Eds.), 4th ed., Pergamon Press, New York
-
Sipes, I. G., and Gandolfi, A. J. (1991). Biotransformation of toxicants. In Casarett and Doull's Toxicology. The Basic Science of Poisons (M. O. Amdur, J. Doull, and C. D. Klaassen, Eds.), 4th ed., pp. 88-126. Pergamon Press, New York.
-
(1991)
Casarett and Doull's Toxicology. The Basic Science of Poisons
, pp. 88-126
-
-
Sipes, I.G.1
Gandolfi, A.J.2
-
27
-
-
0024814724
-
Endocrine profile of WIN 49596 in the rat: A novel androgen receptor antagonist
-
Snyder, B. W., Winneker, R. C., and Batzold, F. H. (1989). Endocrine profile of WIN 49596 in the rat: A novel androgen receptor antagonist. J. Steroid Biochem. 33, 1127-1132.
-
(1989)
J. Steroid Biochem.
, vol.33
, pp. 1127-1132
-
-
Snyder, B.W.1
Winneker, R.C.2
Batzold, F.H.3
-
28
-
-
0018564679
-
Regulation of biliary cholesterol hepatic output in the rat: Dissociation from the rate of hepatic cholesterol synthesis, the size of the hepatic cholesteryl ester pool, and the hepatic uptake of chylomicron cholesterol
-
Turley, S. D., and Dietschy, J. M. (1979). Regulation of biliary cholesterol hepatic output in the rat: Dissociation from the rate of hepatic cholesterol synthesis, the size of the hepatic cholesteryl ester pool, and the hepatic uptake of chylomicron cholesterol. J. Lipid Res. 20, 923-934.
-
(1979)
J. Lipid Res.
, vol.20
, pp. 923-934
-
-
Turley, S.D.1
Dietschy, J.M.2
-
29
-
-
0002322680
-
Cholesterol metabolism and excretion
-
(I. Arias, H. Popper, D. Schachter, and D. A. Shafritz, Eds.), Raven Press, New York
-
Turley, S. D., and Dietschy, J. M. (1982). Cholesterol metabolism and excretion. In The Liver: Biology and Pathobiology (I. Arias, H. Popper, D. Schachter, and D. A. Shafritz, Eds.), pp. 467-492. Raven Press, New York.
-
(1982)
The Liver: Biology and Pathobiology
, pp. 467-492
-
-
Turley, S.D.1
Dietschy, J.M.2
-
30
-
-
0021259840
-
Modulation of the stimulatory effect of pregnenolone-16 alpha-carbonitrile on biliary cholesterol output in the rat by manipulation of the rate of hepatic cholesterol synthesis
-
Turley, S. D., and Dietschy, J. M. (1984). Modulation of the stimulatory effect of pregnenolone-16 alpha-carbonitrile on biliary cholesterol output in the rat by manipulation of the rate of hepatic cholesterol synthesis. Gastroenterology 87, 284-292.
-
(1984)
Gastroenterology
, vol.87
, pp. 284-292
-
-
Turley, S.D.1
Dietschy, J.M.2
-
31
-
-
0037517454
-
Mechanisms of cholestasis
-
(R. G. Meeks, S. D. Harrison, and R. J. Bull, Eds.), CRC Press, Boca Raton, FL
-
Vore, M. (1991). Mechanisms of cholestasis. In Hepatotoxicology (R. G. Meeks, S. D. Harrison, and R. J. Bull, Eds.), pp. 525-568. CRC Press, Boca Raton, FL.
-
(1991)
Hepatotoxicology
, pp. 525-568
-
-
Vore, M.1
-
32
-
-
0025339202
-
Determination of individual bile acids in serum by high performance liquid chromatography
-
Wang, G., Stacey, N. H., and Earl, J. (1990). Determination of individual bile acids in serum by high performance liquid chromatography. Biomed. Chromatogr. 4, 136-140.
-
(1990)
Biomed. Chromatogr.
, vol.4
, pp. 136-140
-
-
Wang, G.1
Stacey, N.H.2
Earl, J.3
-
33
-
-
0024810584
-
Studies on the mechanism of action of WIN 49596: A steroidal androgen receptor antagonist
-
Winneker, R. C., Wagner, M. M., and Batzold, F. H. (1989). Studies on the mechanism of action of WIN 49596: A steroidal androgen receptor antagonist. J. Steroid Biochem. 33, 1133-1138.
-
(1989)
J. Steroid Biochem.
, vol.33
, pp. 1133-1138
-
-
Winneker, R.C.1
Wagner, M.M.2
Batzold, F.H.3
-
34
-
-
0027453654
-
Glucuronidation as a transient intermediate metabolic step in the elimination of (-)-carbovir. Identification of (-)-carbovir-5′-O-glucuronide in rat bile
-
Zimmerman, C. L., Lyer, K. R., Faudskar, A. L., and Remmel, R. P. (1993). Glucuronidation as a transient intermediate metabolic step in the elimination of (-)-carbovir. Identification of (-)-carbovir-5′-O-glucuronide in rat bile. Drug. Metab. Dispos. 21, 902-910.
-
(1993)
Drug. Metab. Dispos.
, vol.21
, pp. 902-910
-
-
Zimmerman, C.L.1
Lyer, K.R.2
Faudskar, A.L.3
Remmel, R.P.4
-
35
-
-
0015442673
-
Effect of spironolactone, pregnenolone-16α-carbonitrile and cortisol on the metabolism and biliary excretion of sulfobromophthalein and phenol-3,6-dibromphthalein disulfonate in rats
-
Zsigmond, G., and Solymoss, B. (1972). Effect of spironolactone, pregnenolone-16α-carbonitrile and cortisol on the metabolism and biliary excretion of sulfobromophthalein and phenol-3,6-dibromphthalein disulfonate in rats. J. Phamacol. Exp. Ther. 183, 499-507.
-
(1972)
J. Phamacol. Exp. Ther.
, vol.183
, pp. 499-507
-
-
Zsigmond, G.1
Solymoss, B.2
|