Characterization and regulation of the latent transforming growth factor-β complex secreted by vascular pericytes

Journal of Cellular Physiology

Volumn 166, Issue 3, 1996, Pages 537-546

  Marra, Fabio ^a,c   Bonewald, Lynda F ^a   Park Snyder, Shaun ^a   Park, In Seok ^a   Woodruff, Kathleen A ^a   Abboud, Hanna E ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; REAGENT; RECOMBINANT PROTEIN;

ABSENCE; ARTICLE; ASSAY; ASSOCIATION; BONE; CELL TYPE; CHROMATOGRAPHY; ELECTRIC POTENTIAL; EXPERIMENT; GENE; GROWTH; HUMAN; LIVER DISEASE; LIVER REGENERATION; MESANGIUM; MESANGIUM CELL; PATHOPHYSIOLOGY; PERICYTE; PRIORITY JOURNAL; ROLE PLAYING; SAMPLE; SECRETION;

ADIPOCYTES; CARRIER PROTEINS; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR MATRIX PROTEINS; GLOMERULAR MESANGIUM; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LATENT TGF-BETA BINDING PROTEINS; LIVER; MICROCIRCULATION; MOLECULAR WEIGHT; PROTEOGLYCANS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029926276     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199603)166:3<537::AID-JCP8>3.0.CO;2-Q     Document Type: Article

References (46)

1. Abboud, H.E. (1993) Growth factors in glomerulonephritis. Kidney Int., 43:252-267.
2. Antonelli-Orlidge, A., Saunders, K.B., Smith, S.R., and D'Amore, P.A (1989) An activated form of transforming growth factor β is produced by cocultures of endothelial cells and pericytes. Proc. Natl. Acad. Sci. U.S.A., 86:4544-4548.
3. 4 treatment. Lab. Invest., 69:283-294.
4. Barnes, J.L., and Abboud, H.E. (1993) Temporal expression of autocrine growth factors corresponds to morphologic features of mesangial proliferation in Habu snake venom-induced glomerulonephritis. Am. J. Pathol, 143:1366-1376.
5. Bascom, C.C., Wolfshohl, J.R., Coffey, R.J., Madisen, L., Webb, N.R., Purchio, A.F., Derynck, R., and Moses, H.L (1989) Complex regulation of transforming growth factor β1, β2, and β3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors β1 and β2. Mol. Cell. Biol, 9:5508-5515.
6. Bonewald, L.F., and Dallas, S.L. (1994) Role of active and latent transforming growth factor β in bone formation. J. Cell. Biochem., 55:350-357.
7. Bonewald, L.F., Wakefield, L., Oreffo, R.O.C., Escobedo, A., Twardzik, D.R., and Mundy, G.R. (1991) Latent forms of transforming growth factor-β (TGFβ) derived from bone cultures: identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGFβ. Mol. Endocrinol., 5:741-751.
8. Border, W.A., and Ruoslahti, E. (1992) Transforming growth factor-β in disease: The dark side of tissue repair. J. Clin. Invest., 90:1-7.
9. Border, W.A., Okuda, S., Languino, L.R., Sporn, M.B., and Ruoslahti, E. (1990) Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1. Nature, 346:371-374.
10. Braun, L., Mead, J.E., Panzica, M., Mikumo, R., Bell, G.I., and Fausto, N. (1988) Transforming growth factor β mRNA increases during liver regeneration: A possible paracrine mechanism of growth regulation. Proc. Natl Acad. Sci. U.S.A., 85.1539-1543.
11. Bruijn, J.A., Roos, A., DeGeus, B., and DeHeer, E. (1994) Transforming growth factor-β and the glomerular extracellular matrix in renal pathology. J. Lab. Clin. Med., 123:34-47.
12. 1 in human fat-storing cells. Gastroenterology, 105:245-253.
13. Castilla, A., Prieto, J., and Fausto, N. (1991) Transforming growth factors β1 and α in chronic liver disease. Effects of interferon alfa therapy. N. Engl. J. Med., 324:933-940.
14. Czaja, M.J., Weiner, F.R., Flanders, K.C., Giambrone, M.-A., Wind, R., Biempica, L., and Zern, M.A. (1989) In vitro and in vivo association of transforming growth factor-β1 with hepatic fibrosis. J. Cell. Biol., 108:2477-2482.
15. Dallas, S.L., Park-Snyder, S., Miyazono, K., Twardzik, D., Mundy, G.R., and Bonewald, L.F. (1994) Characterization and autoregulation of latent transforming growth factor β (TGF-β) in osteoblast-like cell lines: Production of a latent complex lacking the latent TGFβ binding protein. J. Biol. Chem., 269:6815-6822.
16. Davis, B.H., Kramer, R T., and Davidson, N.O. (1990) Retinoic acid modulates rat Ito cell proliferation, collagen, and transforming growth factor β production. J. Clin. Invest., 86:2062-2070.
17. Fisher, L.W., Termine, J.D., and Young, M F. (1989) Deduced protein sequence of small proteoglycan I (biglycan shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species. J. Biol. Chem., 264:4571-4576.
18. Flaumenhaft, R., Abe, M., Sato, Y., Miyazono, K., Harpel, J., Heldin, K.-H., and Rifkin, D.B. (1993) Role of the latent TGF-β binding protein in the activation of latent TGF-β in cocultures of endothelial and smooth muscle cells. J. Cell. Biol., 120:995-1002.
19. Friedman, S.L. (1993) The cellular basis of hepatic fibrosis: Mechanisms and treatment strategies. N. Engl. J. Med., 323:1828-1835.
20. Gentry, L.E., Webb, N.R., Lim, G.J., Brunner, A.M., Ranchalis, J.E., Twardzik, D.R., Lioubin, M.N., Marquardt, H., and Purchio, A.F. (1987) Type I transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells. Mol. Cell. Biol., 7:3418-3427.
21. Horikoshi, S., McCune, B.K., Ray, P.E., Kopp, J.B., Sporn, M.B., and Klotman, P.E. (1991) Water deprivation stimulates transforming growth factor β2 accumulation in the juxtaglomerular apparatus of mouse kidney. J. Clin. Invest., 88:2117-2122.
22. Isaka, Y., Fujiwara, Y., Ueda, N., Kaneda, Y., Kamada, T., and Imai, E. (1993) Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth factor gene into the rat kidney. J. Clin. Invest., 92:2957-2601.
23. Jennings, J.C., Mohan, S., Linkhart, T.A., Widstrom, R., and Baylink, D.J. (1988) Comparison of the biological actions of TGF beta-1 and TGF beta-2: Differential activity in endothelial cells. J. Cell. Physiol., 137:167-172.
24. Kaname, S., Uchida, S., Ogata, E., and Kurokawa, K. (1992) Autocrine secretion of transforming growth factor-beta in cultured rat mesangial cells. Kidney Int., 42:1319-1327.
25. Kanzaki, T., Olofsson, A., Moren, A., Wernsted, C., Hellman, U., Miyazono, K , Claesson-Welsh, L., and Heldin, C.-H. (1990) TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences. Cell, 61:1051-1061.
26. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227:680-685.
27. Lawrence, D.A., Pircher, R., and Jullien, P. (1985) Conversion of a high molecular weight latent TGF-β from chicken embryo fibroblasts into a low molecular weight active TGF-β under acidic conditions. Biochem. Biophys. Res Commun., 133:1026-1034.
28. Lioubin, M.N., Madisen, L., Roth, R.A., and Purchio, A.F. (1991) Characterization of latent transforming growth factor-β2 from monkey kidney cells. Endocrinology, 128:2291-2296.
29. Marra, F., Valente, A.J., Pinzani, M., and Abboud, H.E. (1993) Cultured human fat-storing cells produce monocyte chemotactic protein-1: Regulation by proinflammatory cytokines. J. Clin. Invest., 92.1674-1680.
30. Massague, J. (1990) The transforming growth factor-β family. Annu. Rev. Cell. Biol., 6:597-641.
31. McKay, K., Kondaiah, P., Danielpour, D., Austin, H.A., and Brown, P D. (1990) Expression of transforming growth factor-β1 and β2 in rat glomeruli. Kidney Int., 38:1095-1100.
32. Miyazono, K., Hellman, U., Wernstedt, C , and Heldin, C.-H. (1988) Latent high molecular weight complex of transforming growth factor β1. J. Biol. Chem., 263:6407-6415.
33. Miyazono, K., Olofsson, A., Colosetti, P., and Heldin, C.-H. (1991) A role of the latent TGF-β-binding protein in the assembly and secretion of TGF-β1. E.M.B.O.J., 10:1091-1101.
34. Mullhaupt, B., Feren, A., Fodor, E., and Jones, A. (1994) Liver expression of epidermal growth factor RNA: Rapid increase in immediate-early phase of liver regeneration. J. Biol. Chem., 269:19667-19670.
35. Pfeilschifter, J , and Vosbek, K. (1991) Transforming growth factor β2 inhibits interleukin-1β- and tumour necrosis factor-α-induction of nitric oxide synthase in rat renal mesangial cells. Biochem. Biophys. Res. Commun., 175:371-379.
36. Pircher, R., Jullien, P., and Lawrence, D.A. (1986) -transforming growth factor is stored in human blood platelets as a latent high molecular weight complex. Biochem. Biophys. Res. Commun., 136:30-37.
37. Rosa, F., Roberts, A.B., Danielpour, D., Dart, L.L., Sporn, M.B., and Dawid, I.B. (1988) Mesoderm induction in amphibians: The role of TGF-β2-like factors. Science, 239:783-785.
38. Sato, Y., and Rifkin, D.B. (1989) Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-β1-like molecule by plasmin during coculture. J. Cell. Biol., 109:309-315.
39. Silver, B.J., Jaffer, F.E., and Abboud, H.E. (1989) Platelet-derived growth factor (PDGF) synthesis in mesangial cells: Induction by multiple peptide mitogens. Proc. Natl. Acad. Sci. U.S.A., 86:1056-1060.
40. Taipale, J., Koli, K., and Keski-Oja, J. (1992) Release of transforming growth factor-β1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin. J. Biol. Chem., 267:25378-25384.
41. Taipale, J., Miyazono, K., Heldin, C.-H., and Keski-Oja, J. (1994) Latent transforming growth factor-β1 associates to extracellular matrix via latent TGF-β binding protein J. Cell Biol., 124:171-181.
42. Wakefield, L.M., Smith, D.M , Masui, T., Harris, C.C., and Sporn, M.B. (1987) Distribution and modulation of the cellular receptor for transforming growth factor-beta. J. Cell Biol., 105:965-975.
43. Wakefield, L.M., Smith, D.M., Broz, S., Jackson, M., Levinson, A.P., and Sporn, M.B. (1989) Recombinant TGF-β1 is synthesized as a two-compartment latent complex that shares some structural features with native platelet latent TGF-β1 complex. Growth Factors, 1:203-218.
44. Weiner, F.R., Degli Esposti, S., and Zern, M.A. (1994) A role for transforming growth factor-β in hepatic fibrogenesis. In: Fat-Storing Cells and Liver Fibrosis. Surrenti, C., Casini, A., Milani, S., and Pinzani, M., eds. Kluwer Academic Publ., Dordrecht, pp. 199-208
45. Yamaguchi, Y., Mann, D.M., and Ruoslahti, E. (1990) Negative regulation of transforming growth factor-β by the proteoglycan decorin Nature, 346:371-374.
46. Yamamoto, T., Nakamura, T., Noble, N.A., Ruoslahti, E., and Border, W.A. (1993) Expression of transforming growth factor β is elevated in human and experimental diabetic nephropathy. Proc. Natl. Acad. Sci. U.S.A., 90:1814-1818.