The unusual binding properties of the endothelin receptor antagonist CGS 27830 distinguishes receptor/agonist interactions

Journal of Pharmacology and Experimental Therapeutics

Volumn 276, Issue 1, 1996, Pages 74-83

  Chin, Michael H ^a   Cioffi, Catherine L ^a   Garay, Michelle ^a   Neale, Robert F ^a   Shetty, Suraj S ^a   DelGrande, Dominick ^a   Mugrage, Ben ^a   Sills, Matthew A ^a   Lipson, Kenneth E ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 5 METHOXYCARBONYL 2,6 DIMETHYL 4 (3 NITROPHENYL) 3 PYRIDINECARBOXYLIC ACID ANHYDRIDE; CGS 27830; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; RECEPTOR SUBTYPE; SUCCINYLENDOTHELIN 1 [8-21][9 GLUTAMIC ACID 11,15 ALANINE]; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN MEMBRANE; CEREBELLUM; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; LUNG; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; AORTA, THORACIC; CELL MEMBRANE; CELLS, CULTURED; CEREBELLUM; DIHYDROPYRIDINES; ENDOTHELINS; IODINE RADIOISOTOPES; KINETICS; LIGANDS; LUNG; MALE; MUSCLE CONTRACTION; PEPTIDE FRAGMENTS; PROTEIN BINDING; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN;

EID: 0029925702     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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