MIB l, a promising marker for the classification of cervical intraepithelial neoplasia

Journal of Pathology

Volumn 178, Issue 3, 1996, Pages 268-273

  Bulten, Johan ^a   Van der Laak, Jeroen A W M ^a   Gemmink, Johanna H ^a   Pahlplatz, Martin M M ^a   De Wilde, Peter C M ^a   Hanselaar, Antonius G J M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

CIN; Immunohistochemistry; Ki 67; MIB1; Monoclonal antibody; Proliferation; Quantitative analysis

Indexed keywords

MONOCLONAL ANTIBODY KI 67;

ARTICLE; CANCER CLASSIFICATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX DYSPLASIA;

ANTIBODIES, MONOCLONAL; CERVICAL INTRAEPITHELIAL NEOPLASIA; CERVIX UTERI; EPITHELIUM; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

EID: 0029925052     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1096-9896(199603)178:3<268::aid-path482>3.0.co;2-4     Document Type: Article

References (22)

1. Anderson MC. Female reproductive system. In, Systemic Pathology. 3rd edn. Edinburgh: Churchill Livingstone, 1991: 93-96
2. Gompel C, Silverberg SG. Pathology in Gynecology and Obstetrics. 4th edn Philadelphia. J. B. Lippincott, 1994; 113-115
3. Kurman RJ Blaustein's Pathology of the Female Genital Tract 4th edn. New York: Springer-Verlag, 1994; 244-253
4. Ehrmann RL. Benign to Malignant Progression in Cervical Squamous Epithelium. New York. Igaka-Shoin. 1994, 36-39.
5. Mourits MJE, Peters WJLM, Hollema H, Burger MPM. Three group metaphase as a morphologic criterion of progressive cervical intraepithelial neoplasia. Am J Obstet Gynecol 1992; 167: 591-595
6. Shurbaji MS, Brooks SK, Thurmond MS. Proliferating cell nuclear antigen immunoreactivity in cervical intraepithelial neoplasia and benign cervical epithelium Am J Clin Pathol 1993; 100: 22-26.
7. Mittal KR, Demopoulos RI, Goswami S. Proliferating cell nuclear antigen (cyclin) expression in normal and abnormal cervical squamous epithelia. Am J Surg Pathol 1993; 17: 117-122.
8. McCormick D, Hall PA. The complexities of proliferating cell nuclear antigen Histopathology 1992; 21: 591-594
9. McCormick D, Yu C, Hobbs C. Hall PA The relevance of antibody concentration to the immunohistological quantification of cell proliferationassociated antigens. Histopathology 1993; 22: 543-547.
10. Cattoretti G, Becker MHG, Key G, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB1 and MIB3) detect proliferating cells in microwave-processed, formalin-fixed paraffin sections. J Pathol 1992; 168: 357-363
11. Key G, Becker MHG, Baron B, et al. New Ki-67-equivalent murine monoclonal antibodies (MIB1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope. Lab Invest 1993; 68: 629-636.
12. Gerdes J, Schwab U, Lemke H, Stein H Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation Int J Cancer 1983; 31: 13-20.
13. Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984; 133: 1710-1715.
14. Borgefors G Distance transformations in digital images Comput Vision Graph 1986; 34: 344-371.
15. Hall PA, Levison DA, Woods AL, et al. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms J Pathol 1990; 162: 285-294
16. Casasco A, Casasco M, Cornaglia AJ, Danova M, Giordano M, Calligaro A. Tissue fixation for immunohistochemial detection of proliferating cell nuclear antigen with PC10 monoclonal antibody. Biotcth Histochem 1994; 69: 112-117
17. Gerdes J, Dallenbach F, Lennert K. Growth fractions in malignant nonHodgkin's lymphomas (NHL) as determined in situ with the monoclonal antibody Ki-67. Hematol Oncal 1984; 2: 365-371.
18. Kuenen-Boumeester V, Kwast van der THH, Laarhoven van HAJ, HenzenLogmans SC. Ki-67 staining in histological subtypes of breast carcinoma and fine needle aspiration smears J Clin Pathol 1991; 44: 208-210.
19. Vollmer E, Roessner A, Gerdes J. et al. Improved grading of bone tumors with the monoclonal antibody Ki-67. J Cancer Res Clin Oncol 1986: 112: 281-282.
20. Ooms EHGM, Steenbrugge van GJ. Kwast van der THH, Schröder FH Application of the monoclonal antibody Ki-67 on prostate biopsies to assess the proliferative cell fraction of human prostatic carcinoma J Urol 1991; 145: 81-85.
21. Wong FWS Immunohistochemical detection of proliferating tumor cells in cervical cancer using monoclonal antibody Ki-67 Gynecol Obstet Invest 1994; 37: 123-126.
22. Koss LG. The Papanicolaou test for cervical cancer detection; a triumph and a tragedy. J Am Med Assoc 1989; 261: 737-743.