Effects of excitotoxic lesions of the basal forebrain on MFB self-stimulation

Physiology and Behavior

Volumn 59, Issue 4-5, 1996, Pages 795-806

  Arvanitogiannis, Andreas ^a   Waraczynski, Meg ^a,b   Shizgal, Peter ^a  

^a and Applied Physiology   (Canada)

^b UNIVERSITY OF WISCONSIN WHITEWATER   (United States)

Author keywords

Excitotoxic lesions; Lateral Hypothalamus; Lateral preoptic area; NMDA; Rat; Self stimulation; Substantia innominata; Ventral tegmental area

Indexed keywords

EXCITOTOXIN; N METHYL DEXTRO ASPARTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BRAIN INJURY; CONTROLLED STUDY; DEMYELINATION; LATERAL HYPOTHALAMUS; MALE; MEDIAL FOREBRAIN BUNDLE; NONHUMAN; PEDUNCULAR ANSA; PREOPTIC AREA; PRIORITY JOURNAL; RAT; SELF STIMULATION; VENTRAL TEGMENTUM;

EID: 0029924990     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/0031-9384(95)02157-4     Document Type: Article

References (36)

1. Anderson, R.; Miliaressis, E. Does the MFB convey functionally different reward signals? Behav. Brain Res. 60:55-61; 1994.
2. Bielajew, C.; Shizgal, P. Behaviourally derived measures of conduction velocity in the substrate for rewarding medial forebrain bundle stimulation. Brain Res. 237:107-119; 1982.
3. Bielajew, C.; Shizgal, P. Evidence implicating descending fibers in self-stimulation of the medial forebrain bundle. J. Neurosci. 6:919-929; 1986.
4. Coffey, P. J.; Perry, V. H.; Rawlins, J. N. P. An investigation into the early stages of the inflammatory response following ibotenic acid-induced neuronal degeneration. Neuroscience 35:121-132; 1990.
5. Coffey, P. J.; Perry, V. H.; Allen, Y.; Sinden, J.; Rawlins, J. N. P. Ibotenic acid induced demyelination in the central nervous system: A consequence of a local inflammatory response. Neurosci. Lett. 84:178-184; 1988.
6. Conover, K.; Shizgal, P. Competition and summation between rewarding effects of sucrose and lateral hypothalamic stimulation in the rat. Behav. Neurosci. 108(3):537-548; 1994.
7. Edmonds, D. E.; Gallistel, C. R. Parametric analysis of brain stimulation reward in the rat: III. Effect of performance variables on the reward summation function. J. Comp. Physiol. Psychol. 87:876-883; 1974.
8. Fouriezos, G. A.; Bielajew, C.; Pagotto, W. Task difficulty increases thresholds of rewarding brain stimulation. Behav. Brain Res. 37:1-7; 1990.
9. Gallistel, C. R.; Beagley, G. Specificity of brain stimulation reward in the rat. J. Comp. Physiol. Psychol. 76:199-205; 1971.
10. Gallistel, C. R.; Freyd, G. Quantitative determination of the effects of catecholaminergic agonists and antagonists on the rewarding efficacy of brain stimulation. Pharmacol. Biochem. Behav. 26:731-741; 1987.
11. Gallistel, C. R.; Shizgal, P.; Yeomans, J. S. A portrait of the substrate for self-stimulation. Psychol. Rev. 88:228-273; 1981.
12. Gallistel, C. R.; Leon M. Measuring the subjective magnitude of brain stimulation reward by titration with rate of reward. Behav. Neurosci. 105:913-925; 1991.
13. Heyman, G. How drugs affect cells and reinforcement: Formal analogies. In: Church, R. M.; Commons, M. L.; Stellar, J. R.; Wagner, A. R., eds. Quantitative analyses of behaviour: Biological determinants of behavior. vol. 7. Hillsdale, NJ: Lawrence Erlbaum Associates; 1988:157-182.
14. Janas, J. D.; Stellar, J. R. Effects of knife cut-lesions of the medial forebrain bundle in self-stimulating rats. Behav. Neurosci. 101:832-845; 1987.
15. Miliaressis, E.; Rompré, P.-P.; Laviolette, P.; Phillippe, L.; Coulombe, D. The curve-shift paradigm in self-stimulation. Physiol. Behav. 37:85-91; 1986.
16. Moghaddam, B.; Bunney, B. S. Ionic components of microdyalisis perfusing solution alters the pharmacological responsiveness and basal outflow of striatal dopamine. J. Neurochem. 53:652-654; 1989.
17. Mundl, W. J. A constant-current stimulator. Physiol. Behav. 24:991-993; 1980.
18. Murray, B.; Shizgal, P. Collision-like effects obtained from self-stimulation sites in the anterior lateral hypothalamic and ventral tegmental areas. Physiol. Behav. (in press).
19. Murray, B.; Shizgal, P. Electrophysiological properties of medial forebrain bundle fibers arising in the basal forebrain. Physiol. Behav. (in press).
20. Murray, B.; Shizgal, P. Attenuation of medial forebrain bundle reward by rostral lateral hypothalamic lesions depends on stimulation site and current. Behav. Brain Res. 1996.
21. Murray, B. Shizgal, P. Anterolateral lesions of the medial forebrain bundle increases the frequency threshold for self-stimulation of the lateral hypothalamus and ventral tegmental area in the rat. Psychobiology 19:135-146; 1991.
22. Olds, J.; Milner, P. M. Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J. Comp. Physiol. Psychol. 47:419-427; 1954.
23. Paxinos, G.; Watson, C. The rat brain in stereotaxic coordinates. 2nd ed. Sydney: Academic Press; 1986.
24. Rompré, P.-P.; Shizgal, P. Electrophysiological characteristics of neurons in forebrain regions implicated in self-stimulation of the medial forebrain bundle in the rat. Brain Res. 364:338-349; 1986.
25. Shizgal, P.; Murray, B. Neuronal basis of intracranial self-stimulation. In: Liebman, J. M.; Cooper, S. J., eds. The neuropharmacological basis of reward. Oxford: Oxford University Press; 1989:106-163.
26. Shizgal, P.; Schindler, D.; Rompré, P.-P. Forebrain neurons driven by rewarding stimulation of the medial forebrain bundle in the rat: Comparison of psychophysical and electrophysiological estimates of refractory periods. Brain Res. 499:234-248; 1989.
27. Simmons, J. M.; Gallistel, C. R. Saturation of subjective reward magnitude as a function of current and pulse frequency. Behav. Neurosci. 108:151-160; 1994.
28. Stellar, J. R. Investigating the neural circuitry of brain stimulation reward. Prog. Psychobiol. Physiol. Psychol. 14:235-294; 1990.
29. Stellar, J. R.; Hall, F. S.; Waraczynski, M. The effects of excitotoxin lesions of the lateral hypothalamus on self-stimulation reward. Brain Res. 541:29-40; 1991.
30. Stellar, J. R.; Waraczynski, M.; Wong, K. The reward summation function in hypothalamic self-stimulation. In: Church, R. M.; Commons, M. L.; Stellar, J. R.; Wagner, A. R., eds. Quantitative analyses of behaviour: Biological determinants of behavior. vol. 7. Hillsdale, NJ: Lawrence Erlbaum Associates; 1988:31-58.
31. Waraczynski, M. Basal forebrain knife cuts and medial forebrain bundle self-stimulation. Brain Res. 438:8-22; 1988.
32. Waraczynski, M.; Conover, K.; Shizgal, P. Rewarding effectiveness of caudal MFB stimulation is unaltered following DMH lesions. Physiol. Behav. 52:211-218; 1992.
33. Waraczynski, M. A.; Ng Cheong-Ton, M.; Shizgal, P. Failure of amygdaloid lesions to increase the threshold for self-stimulation of the lateral hypothalamus and ventral tegmental area. Behav. Brain Res. 40:159-168; 1990.
34. Waraczynski, M.; Shizgal, P. Self-stimulation of the MFB following parabrachial lesions. Physiol. Behav. 58:559-566; 1995.
35. Yednock, T. A.; Cannon, C.; Fritz, L. C.; Sanchez-Madrid, F.; Steinamn, L.; Karin, N. Prevention of experimental autoimmune encephalomyelitis by antibodies against a4b1 integrin. Nature. 356:63-66; 1992.
36. Yeomans, J. Mechanisms of brain-stimulation reward. Prog. Psychobiol. Physiol. Psychol. 13:227-266: 1988.