메뉴 건너뛰기




Volumn 52, Issue 1, 1996, Pages 157-166

Enhancement of ricin toxin A chain immunotoxin activity: Synthesis, ionophoretic ability, and in vitro activity of monensin derivatives

Author keywords

drug targeting; enhancer; immunotoxin; monensin; ricin A chain

Indexed keywords

IMMUNOTOXIN; MONENSIN; MONENSIN CILIATINE AMIDE; MONENSIN DERIVATIVE; MONENSIN DIMETHYLAMINOETHYLAMIDE; MONENSIN METHYL ESTER; MONENSIN SQUALANE AMIDE; MONENSIN SQUALENE AMIDE; MONENSIN TAURINE AMIDE; MONENSIN TYRAMIDE; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT; RICIN A; UNCLASSIFIED DRUG;

EID: 0029924927     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00176-1     Document Type: Article
Times cited : (10)

References (48)
  • 1
    • 0026613775 scopus 로고
    • Antibody conjugates for the treatment of cancer
    • Pietersz GA and McKenzie JFC, Antibody conjugates for the treatment of cancer. Immunol Rev 127: 57-80, 1992.
    • (1992) Immunol Rev , vol.127 , pp. 57-80
    • Pietersz, G.A.1    McKenzie, J.F.C.2
  • 2
    • 0026593688 scopus 로고
    • Blocking effect of human serum but not of cerebrospinal fluid on ricin A chain immunotoxin potentiation by monensin or carrier protein-monensin conjugates
    • Candiani C, Franceschi A, Chignola C, Pasti M, Anselmi C, Benoni G, Tridente G and Colombatti M, Blocking effect of human serum but not of cerebrospinal fluid on ricin A chain immunotoxin potentiation by monensin or carrier protein-monensin conjugates. Cancer Res 52: 623-630, 1992.
    • (1992) Cancer Res , vol.52 , pp. 623-630
    • Candiani, C.1    Franceschi, A.2    Chignola, C.3    Pasti, M.4    Anselmi, C.5    Benoni, G.6    Tridente, G.7    Colombatti, M.8
  • 3
  • 4
    • 0023195687 scopus 로고
    • Complete suppression of in vivo growth of human leukemia cells by specific immunotoxin: Nude mouse model
    • Hara H and Seon BK, Complete suppression of in vivo growth of human leukemia cells by specific immunotoxin: nude mouse model. Proc Natl Acad Sci USA 84: 3390-3394, 1987.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3390-3394
    • Hara, H.1    Seon, B.K.2
  • 5
    • 0023240807 scopus 로고
    • Antitumor activity of intraperitoneal immunotoxin in a nude mouse model of human malignant mesothelioma
    • Griffin TW, Richardson C, Houston LL, LePage D, Bogden A and Raso V, Antitumor activity of intraperitoneal immunotoxin in a nude mouse model of human malignant mesothelioma. Cancer Res 47: 4266-4270, 1987.
    • (1987) Cancer Res , vol.47 , pp. 4266-4270
    • Griffin, T.W.1    Richardson, C.2    Houston, L.L.3    LePage, D.4    Bogden, A.5    Raso, V.6
  • 6
    • 0024145322 scopus 로고
    • Immunotoxin therapy assessment by animal models
    • (Ed. Frankel AE), Kluwer Academic Publishers, Boston
    • Griffin TW, Morgan AC and Blythman HE, Immunotoxin therapy assessment by animal models. In: Immunotoxins (Ed. Frankel AE), pp. 433-455. Kluwer Academic Publishers, Boston, 1988.
    • (1988) Immunotoxins , pp. 433-455
    • Griffin, T.W.1    Morgan, A.C.2    Blythman, H.E.3
  • 7
    • 0023722170 scopus 로고
    • Efficient transplantation of human non-T leukemia cells into nude mice and induction of complete regression of the transplanted distinct tumors by ricin A chain conjugates of monoclonal antibody
    • Hara H, Luo Y, Haruta Y and Seon BK, Efficient transplantation of human non-T leukemia cells into nude mice and induction of complete regression of the transplanted distinct tumors by ricin A chain conjugates of monoclonal antibody. Cancer Res 48: 4673-4680, 1988.
    • (1988) Cancer Res , vol.48 , pp. 4673-4680
    • Hara, H.1    Luo, Y.2    Haruta, Y.3    Seon, B.K.4
  • 11
    • 0024437058 scopus 로고
    • Phase I study of monoclonal antibody-ricin A chain immunotoxin Xomazyme 791 in patients with metastatic colon cancer
    • Byers VS, Rodvien R, Grant K, Durrant LG, Hudson KH, Baldwin RW and Scannon PJ, Phase I study of monoclonal antibody-ricin A chain immunotoxin Xomazyme 791 in patients with metastatic colon cancer. Cancer Res 49: 6153-6160, 1989.
    • (1989) Cancer Res , vol.49 , pp. 6153-6160
    • Byers, V.S.1    Rodvien, R.2    Grant, K.3    Durrant, L.G.4    Hudson, K.H.5    Baldwin, R.W.6    Scannon, P.J.7
  • 14
    • 0026535102 scopus 로고
    • Internalization and intracellular fate of anti-CD5 monoclonal antibody and anti-CD5-ricin A chain immunotoxin in human leukemic T cells
    • Ravel S, Colombatti M and Casellas P, Internalization and intracellular fate of anti-CD5 monoclonal antibody and anti-CD5-ricin A chain immunotoxin in human leukemic T cells. Blood 79: 1511-1517, 1992.
    • (1992) Blood , vol.79 , pp. 1511-1517
    • Ravel, S.1    Colombatti, M.2    Casellas, P.3
  • 15
    • 0024365017 scopus 로고
    • Rate of internalization of an immunotoxin correlates with cytotoxic activity against tumor cells
    • Wargalla UC and Reisfeld RA, Rate of internalization of an immunotoxin correlates with cytotoxic activity against tumor cells. Proc Natl Acad Sci USA 86: 5146-5150, 1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5146-5150
    • Wargalla, U.C.1    Reisfeld, R.A.2
  • 16
    • 0025091436 scopus 로고
    • 2- (ricin A chain) immunotoxin into human T-leukemic cells
    • 2- (ricin A chain) immunotoxin into human T-leukemic cells. Eur J Biochem 192: 469-473, 1990.
    • (1990) Eur J Biochem , vol.192 , pp. 469-473
    • Ravel, S.1    Casellas, P.2
  • 18
    • 0005595441 scopus 로고
    • Role of endocytous and receptor recycling in ligand-toxin and antibody-toxin conjugate activity
    • (Ed. Vogel C), Oxford University Press, New York
    • Youle RJ and Neville DM, Role of endocytous and receptor recycling in ligand-toxin and antibody-toxin conjugate activity. In: Immunoconjugates, Antibody conjugates in radioimaging and therapy of cancer (Ed. Vogel C), pp. 153-169, Oxford University Press, New York, 1987.
    • (1987) Immunoconjugates, Antibody Conjugates in Radioimaging and Therapy of Cancer , pp. 153-169
    • Youle, R.J.1    Neville, D.M.2
  • 19
    • 0023693953 scopus 로고
    • Endocytosis and intracellular routing of an antibody-ricin A chain conjugate
    • Calafat J, Molthoff C, Janssen H and Hilkens J, Endocytosis and intracellular routing of an antibody-ricin A chain conjugate. Cancer Res 48: 3822-3827, 1988.
    • (1988) Cancer Res , vol.48 , pp. 3822-3827
    • Calafat, J.1    Molthoff, C.2    Janssen, H.3    Hilkens, J.4
  • 21
    • 0021145615 scopus 로고
    • Selective antitumor effect on L10 hepatocarcinoma cells of a potent immunoconjugate composed of the A chain of abrin and a monoclonal antibody to a hepatoma-associated antigen
    • Hwang KM, Foon KA, Cheung PH, Pearson JW and Olham RK, Selective antitumor effect on L10 hepatocarcinoma cells of a potent immunoconjugate composed of the A chain of abrin and a monoclonal antibody to a hepatoma-associated antigen. Cancer Res 44: 4578-4586, 1984.
    • (1984) Cancer Res , vol.44 , pp. 4578-4586
    • Hwang, K.M.1    Foon, K.A.2    Cheung, P.H.3    Pearson, J.W.4    Olham, R.K.5
  • 23
    • 0014469315 scopus 로고
    • Action of certain antibodies on mitochondrial, erythrocyte and artificial phospholipid membranes. Role of induced proton permeability
    • Henderson PJF, McGivan D and Chappel JB, Action of certain antibodies on mitochondrial, erythrocyte and artificial phospholipid membranes. Role of induced proton permeability. Biochem J 111: 521-524, 1969.
    • (1969) Biochem J , vol.111 , pp. 521-524
    • Henderson, P.J.F.1    McGivan, D.2    Chappel, J.B.3
  • 24
    • 0014932605 scopus 로고
    • Effects of ionophores antibiotics in chloroplasts
    • Shavit N, Degani H and SanPietro A, Effects of ionophores antibiotics in chloroplasts. Biochim Biophys Acta 216: 208-211, 1970.
    • (1970) Biochim Biophys Acta , vol.216 , pp. 208-211
    • Shavit, N.1    Degani, H.2    SanPietro, A.3
  • 25
    • 0021194783 scopus 로고
    • Kinetics of cytotoxicity induced by immunotoxins. Enhancement by lysosomotropic amines and carboxylic ionophores
    • Casellas P, Bourrie JP, Gros P and Jansen FK, Kinetics of cytotoxicity induced by immunotoxins. Enhancement by lysosomotropic amines and carboxylic ionophores. J Biol Chem 259: 9359-9364, 1984.
    • (1984) J Biol Chem , vol.259 , pp. 9359-9364
    • Casellas, P.1    Bourrie, J.P.2    Gros, P.3    Jansen, F.K.4
  • 26
    • 0021327184 scopus 로고
    • Inhibition of human acute lymphoblastic leukemia cells by immunotoxin: Potentiation by chloroquine
    • Ramakrishnan S and Houston LL, Inhibition of human acute lymphoblastic leukemia cells by immunotoxin: potentiation by chloroquine. Science 223: 58-61, 1984.
    • (1984) Science , vol.223 , pp. 58-61
    • Ramakrishnan, S.1    Houston, L.L.2
  • 27
    • 0025363534 scopus 로고
    • Carrier protein-monensin conjugates: Enhancement of immunotoxin cytotoxicity and potential in tumor treatment
    • Colombatti M, Dell'Arciprete L, Chignola R and Tridente G, Carrier protein-monensin conjugates: enhancement of immunotoxin cytotoxicity and potential in tumor treatment. Cancer Res 50: 1385-1391, 1990.
    • (1990) Cancer Res , vol.50 , pp. 1385-1391
    • Colombatti, M.1    Dell'Arciprete, L.2    Chignola, R.3    Tridente, G.4
  • 28
    • 0025240867 scopus 로고
    • Alteration of intracellular traffic by monensin: Mechanism, specificity and relationship to toxicity
    • Mollenhauer HH, Morrè DJ and Rowe LD, Alteration of intracellular traffic by monensin: mechanism, specificity and relationship to toxicity. Biochim Biophys Acta 1031: 225-246, 1990.
    • (1990) Biochim Biophys Acta , vol.1031 , pp. 225-246
    • Mollenhauer, H.H.1    Morrè, D.J.2    Rowe, L.D.3
  • 29
    • 0026720878 scopus 로고
    • Golgi vacuolization and immunotoxin enhancement by monensin and perhexilin depend on a serum protein
    • Jansen FK, Jansen A, Derocq JM, Carriere D, Carayon P, Veas F and Jaffrezou JP, Golgi vacuolization and immunotoxin enhancement by monensin and perhexilin depend on a serum protein. J Biol Chem 267: 12577-12582, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 12577-12582
    • Jansen, F.K.1    Jansen, A.2    Derocq, J.M.3    Carriere, D.4    Carayon, P.5    Veas, F.6    Jaffrezou, J.P.7
  • 31
    • 0020635123 scopus 로고
    • Perturbation of vesicular traffic with carboxylic ionophore monensin
    • Tartakoff AM, Perturbation of vesicular traffic with carboxylic ionophore monensin. Cell 32: 1026-1028, 1983.
    • (1983) Cell , vol.32 , pp. 1026-1028
    • Tartakoff, A.M.1
  • 32
    • 0020724143 scopus 로고
    • Recycling receptors: The round-trip itinerary of migrant membrane proteins
    • Brown MS, Anderson RGW and Goldstein JL, Recycling receptors: the round-trip itinerary of migrant membrane proteins. Cell 32: 663-667, 1983.
    • (1983) Cell , vol.32 , pp. 663-667
    • Brown, M.S.1    Anderson, R.G.W.2    Goldstein, J.L.3
  • 33
    • 0021231808 scopus 로고
    • Carboxylic ionophores enhance the cytotoxic potency of ligand and antibody-delivered ricin A chain
    • Raso V and Lawrence J, Carboxylic ionophores enhance the cytotoxic potency of ligand and antibody-delivered ricin A chain. J Exp Med 160: 1234-1240, 1984.
    • (1984) J Exp Med , vol.160 , pp. 1234-1240
    • Raso, V.1    Lawrence, J.2
  • 34
    • 0000599566 scopus 로고
    • Design and synthesis of lithium ionophores for an ion-selective electrode by chemical modification of natural carboxylic polyether antibiotic monensin
    • Tohda K, Suzuki K, Kosuge N, Watanabe K, Nagashima H, Inoue H and Shirai T, Design and synthesis of lithium ionophores for an ion-selective electrode by chemical modification of natural carboxylic polyether antibiotic monensin. Anal Chem 62: 936-942, 1990.
    • (1990) Anal Chem , vol.62 , pp. 936-942
    • Tohda, K.1    Suzuki, K.2    Kosuge, N.3    Watanabe, K.4    Nagashima, H.5    Inoue, H.6    Shirai, T.7
  • 35
    • 0014851618 scopus 로고
    • Relationship between lipophilic character and hemolitic activity of testosterone esters
    • Biagi GL, Guerra MC and Barbaro AM, Relationship between lipophilic character and hemolitic activity of testosterone esters. J Med Chem 13: 944-948, 1970.
    • (1970) J Med Chem , vol.13 , pp. 944-948
    • Biagi, G.L.1    Guerra, M.C.2    Barbaro, A.M.3
  • 36
    • 0014675062 scopus 로고
    • Partition data of cephalosporins determined by means of reversal-phase thin-layer chromatography
    • Biagi GL, Barbaro AM and Guerra MC, Partition data of cephalosporins determined by means of reversal-phase thin-layer chromatography. J Chromat 44: 195-198, 1969.
    • (1969) J Chromat , vol.44 , pp. 195-198
    • Biagi, G.L.1    Barbaro, A.M.2    Guerra, M.C.3
  • 40
    • 2642714342 scopus 로고
    • Fluorescence probe measurement of the intralysosomal pH in lung cells and the perturbation of pH by various agents
    • Ohkuma S and Poole B, Fluorescence probe measurement of the intralysosomal pH in lung cells and the perturbation of pH by various agents. Proc Natl Acad Sci USA 73: 3327-3331, 1978.
    • (1978) Proc Natl Acad Sci USA , vol.73 , pp. 3327-3331
    • Ohkuma, S.1    Poole, B.2
  • 41
    • 0025606525 scopus 로고
    • Distribution of endocytosed molecules to intracellular acidic environments correlates with immunotoxin activity
    • Chignola R, Colombatti M, Dell'Arciprete L, Candiani C and Tridente G, Distribution of endocytosed molecules to intracellular acidic environments correlates with immunotoxin activity, Int J Cancer 46: 1117-1123, 1990.
    • (1990) Int J Cancer , vol.46 , pp. 1117-1123
    • Chignola, R.1    Colombatti, M.2    Dell'Arciprete, L.3    Candiani, C.4    Tridente, G.5
  • 42
    • 0024849184 scopus 로고
    • Immunotoxins: A clinical review of their use in the treatment of malignancies
    • Hertler AA, Frankel AE, Immunotoxins: a clinical review of their use in the treatment of malignancies. J Clin Oncol 7: 1932-1935, 1989.
    • (1989) J Clin Oncol , vol.7 , pp. 1932-1935
    • Hertler, A.A.1    Frankel, A.E.2
  • 43
    • 0027408602 scopus 로고
    • The current status of immunotoxins: An overview of experimental and clinical studies as presented at the Third International Symposium on immunotoxins
    • Uckun FM and Frankel AE, The current status of immunotoxins: an overview of experimental and clinical studies as presented at the Third International Symposium on immunotoxins. Leukemia 7: 341-345, 1993.
    • (1993) Leukemia , vol.7 , pp. 341-345
    • Uckun, F.M.1    Frankel, A.E.2
  • 44
    • 0023204840 scopus 로고
    • Enhancement of the cytotoxic effect of anti-carcinoembrionic antigen immunotoxin by adenovirus and carboxylic ionophores
    • Griffin TW, Childs LR, FitzGerald DJP and Levin LV, Enhancement of the cytotoxic effect of anti-carcinoembrionic antigen immunotoxin by adenovirus and carboxylic ionophores. J Natl Cancer Inst 79: 679-685, 1987.
    • (1987) J Natl Cancer Inst , vol.79 , pp. 679-685
    • Griffin, T.W.1    Childs, L.R.2    FitzGerald, D.J.P.3    Levin, L.V.4
  • 45
    • 0021996468 scopus 로고
    • Endocytosis of an antibody ricin A-chain conjugate (immuno-A-toxin) adsorbed on colloidal gold. Effects of ammonium chloride and monensin
    • Carriere D, Casellas P, Richer G, Gros P, Jansen FK, Endocytosis of an antibody ricin A-chain conjugate (immuno-A-toxin) adsorbed on colloidal gold. Effects of ammonium chloride and monensin. Exp Cell Res 156: 327-340, 1985.
    • (1985) Exp Cell Res , vol.156 , pp. 327-340
    • Carriere, D.1    Casellas, P.2    Richer, G.3    Gros, P.4    Jansen, F.K.5
  • 46
    • 0000241799 scopus 로고
    • pH and the recycling of transferrin during receptor-mediated endocytosis
    • Dautry-Varsat A, Ciechanover A, Lodish HF, pH and the recycling of transferrin during receptor-mediated endocytosis. Proc Natl Acad Sci USA 80: 2250-2262, 1983.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 2250-2262
    • Dautry-Varsat, A.1    Ciechanover, A.2    Lodish, H.F.3
  • 47
    • 0026665486 scopus 로고
    • Studies on the chemical modification of monensin IV. Synthesis, sodium ionpermeability and biological activity of 7-O-acyl and 7-O-alkyl monensins
    • Nakamura A, Nagai S, Takahashi T, Malhan R, Murakami N, Ueda T, Sakakibara J and Asano M, Studies on the chemical modification of monensin IV. Synthesis, sodium ionpermeability and biological activity of 7-O-acyl and 7-O-alkyl monensins. Chem Pharm Bull 40: 2331-2337, 1992.
    • (1992) Chem Pharm Bull , vol.40 , pp. 2331-2337
    • Nakamura, A.1    Nagai, S.2    Takahashi, T.3    Malhan, R.4    Murakami, N.5    Ueda, T.6    Sakakibara, J.7    Asano, M.8
  • 48
    • 0018719091 scopus 로고
    • Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin moddecin into HeLa cells
    • Sandvig K, Olsnes S and Pihl A, Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin moddecin into HeLa cells. Biochem Biophys Res Comm 90: 648-655, 1979.
    • (1979) Biochem Biophys Res Comm , vol.90 , pp. 648-655
    • Sandvig, K.1    Olsnes, S.2    Pihl, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.