Ischemic/reperfused myocardium can express recombinant protein following direct DNA or retroviral injection

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 1, 1996, Pages 133-140

  Prentice, Howard ^a,c   Kloner, Robert A ^a,b   Li, Yuwei ^b   Newman, Laurie ^b   Kedes, Larry ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b GOOD SAMARITAN HOSPITAL   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

DNA injection; Gene therapy; Myocardial infarction; Retrovirus

Indexed keywords

BETA GALACTOSIDASE; DNA; LUCIFERASE; RECOMBINANT PROTEIN; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA TRANSCRIPTION; DOG; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; RAT; REPORTER GENE; RETROVIRUS; ROUS SARCOMA ONCOVIRUS;

ANIMALIA; CANIS FAMILIARIS; ONCOVIRINAE; ROUS SARCOMA VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0029924681     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0013     Document Type: Article

References (25)

1. ACSADI G, JIAO SS, JANI A, DUKE D, WILLIAMS P, CHONG W, WOLFF JA, 1991. Direct gene transfer and expression into rat heart in vivo. New Biol 3: 71-81.
2. AMACHER SL, BUSKIN JN, HAUSCHKA SD, 1993. Multiple regulatory elements contribute differentially to muscle creatine kinase enhancer activity in skeletal and cardiac muscle. Mol Cell Biol 13: 2753-2764.
3. ANDERSON WF, 1992. Human gene therapy. Science 256: 808-13.
4. BRASIER AR, TATE JE, HABENER JF, 1989. Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. BioTech 7: 1116-1122.
5. BUTTRICK PM, KASS A, KITSIS RN, KAPLAN ML, LEINWAND LA, 1992. Behavior of genes directly injected into the rat heart in vivo. Circ Res 70: 193-8.
6. FRENCH BA, MAZUR W, GESKE RS, BOLLI R, 1994. Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors. Circulation 90: 2414-24.
7. HALE SL, KLONER RA, 1987. Effect of early coronary artery reperfusion on infarct development in a model of low collateral flow. Cardiovasc Res 21: 668-673.
8. HALE SL, VIVALDI MT, KLONER RA, 1986. Fluorescent microspheres: a new tool for visualization of Ischemic Myocardium in Rats. Am J Physiol 251: H863-H868.
9. JIAO S, WILLIAMS P, BERG RK, HODGEMAN BA, LIU L, REPETTO G, WOLFF JA, 1992. Direct gene transfer into nonhuman primate myofibers in vivo. Human Gene Therapy 3: 21-33.
10. KITSIS RN, BUTTRICK PM, MCNALLY EM, KAPLAN ML, LEINWAND LA, 1991. Hormonal modulation of a gene injected into rat heart in vivo. Proc Natl Acad Sci USA 88:4138-42.
11. KLONER RA, GANOTE CE, WHALEN D, JENNINGS RB, 1974. Effect of a transient period of ischemia on myocardial cells II. Fine structure during the first few minutes of reflow. Am J Pathol 74: 399-422.
12. KLONER RA, FISHBEIN MC, HARE CS, MAROKO PR, 1979. Early Ischemic Ultrastructural and Histochemical Alterations in the Myocardium of the Rat Following Coronary Artery Occlusion. Exp Mol Path 30: 129-143.
13. LI Y, KLONER RA, 1992. Cardioprotective effects of ischaemic preconditioning are not mediated by prostanoids. Cardiovasc Res 26: 226-31.
14. LIN H, PARMACEK MS, MORLE G, BOLLING S, LEIDEN J, 1990. Expression of recombinant genes in myocardium in vivo after direct injection of DNA. Circulation 82: 2217-2221.
15. MILLER AD, 1992. Human gene therapy comes of age. Nature 357: 455-60.
16. MILLER DG, ADAM MA, MILLER AD, 1990. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 12: 4239-4242.
17. MULLIGAN RC, 1993. The basic science of gene therapy. Science 260: 926-932.
18. NABEL EG, PLAUTZ G, BOYCE FM, STANLEY JC NABEL GJ, 1989. Recombinant gene expression in vivo within endothelial cells of the arterial wall. Science 244: 1342-4.
19. NABEL EG, PLAUTZ G, NABEL GJ, 1991. Gene transfer into vascular cells. J Am Coll Cardiol 17: 189B-194B.
20. PARMACEK MS, VORA AJ, SHEN T, BARR E, JUNG F, LEIDEN JM, 1992. Identification and Characterization of a Cardiac-Specific Transcriptional Regulatory Element in the Slow/Cardiac Troponin C Gene. Mol Cell Biol 12: 1967-1976.
21. PRENTICE H, KLONER RA, PRYGOZY T, CHRISTENSEN T, NEWMAN L, YUWEI L, KEDES L, 1994. Tissue restricted gene expression assayed by direct DNA injection into cardiac and skeletal muscle. J Mol Cell Cardiol 26: 1393-1401.
22. VON HARSDORF R, SCHOTT RJ, SHEN T, VATNER SF, MAHDAVI V, NADAL GINARD B, 1993. Gene injection into canine myocardium as a useful model for studying gene expression in the heart of large mammals. Circ Res 72: 688-95.
23. WOLFF JA, DOWTY ME, JIAO S, REPETTO G, BERG RK, LUDTKE JJ, WILLIAMS P, SLAUTTERBACK DB, 1992. Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle. J Cell Sci 103: 1249-59.
24. WOLFF JA, MALONE RW, WILLIAMS P, CHONG W, ACSADI G, JANI A, FELGNER PL, 1990. Direct gene transfer into mouse muscle in vivo. Science 247: 1465-8.
25. WOLFF JA, WILLIAMS P, ACSADI G, JIAO S, JANI A, CHONG W, 1991. Conditions affecting direct gene transfer into rodent muscle in vivo. Biotechniques 11: 474-485.