Bioactivation of estrone and its catechol metabolites to quinoid-glutathione conjugates in rat liver microsomes

Chemical Research in Toxicology

Volumn 9, Issue 2, 1996, Pages 492-499

  Iverson, Suzanne L ^a   Shen, Li ^a   Anlar, Nilgun ^a   Bolton, Judy L ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BENZOQUINONE; 2 HYDROXYESTRONE; CATECHOL ESTROGEN; CYTOCHROME P450; DRUG METABOLITE; ESTRONE; ESTRONE DERIVATIVE; QUINONE DERIVATIVE; TETRALIN DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CHEMICAL CARCINOGENESIS; CHEMICAL STRUCTURE; DRUG ACTIVATION; ENZYME ACTIVE SITE; GLUTATHIONE METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOMERISM; LIVER MICROSOME; MALE; MASS SPECTROMETRY; NONHUMAN; OXIDATION; RAT; REACTION ANALYSIS;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; ESTRONE; GLUTATHIONE; HYDROXYESTRONES; INDOLEQUINONES; INDOLES; MALE; MICROSOMES, LIVER; PROTEIN BINDING; QUINONES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0029924611     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx950178c     Document Type: Article

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