메뉴 건너뛰기




Volumn 60, Issue 3, 1996, Pages 363-378

Inducible expression of cyclin D1 in T-47D human breast cancer cells is sufficient for Cdk2 activation and pRB hyperphosphorylation

Author keywords

CDK activity; cell cycle control; cyclin D1 function; G1 phase; pRB phosphorylation

Indexed keywords

CYCLINE; PROTAMINE KINASE;

EID: 0029924608     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960301)60:3<363::AID-JCB8>3.0.CO;2-U     Document Type: Article
Times cited : (30)

References (64)
  • 5
    • 0028039027 scopus 로고
    • CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1
    • Bates S, Bonetta L, MacAllan D, Parry D, Holder A, Dickson C, Peters G (1994) CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1. Oncogene 9:71-79.
    • (1994) Oncogene , vol.9 , pp. 71-79
    • Bates, S.1    Bonetta, L.2    MacAllan, D.3    Parry, D.4    Holder, A.5    Dickson, C.6    Peters, G.7
  • 6
    • 0024439444 scopus 로고
    • The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
    • Buchkovich K, Duffy LA, Harlow E (1989) The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58:1097-1105.
    • (1989) Cell , vol.58 , pp. 1097-1105
    • Buchkovich, K.1    Duffy, L.A.2    Harlow, E.3
  • 8
    • 0026216808 scopus 로고
    • Autocrine production of insulin-like growth factor II using an inducible expression system results in reduced estrogen sensitivity of MCF-7 human breast cancer cells
    • Daly RJ, Harris WH, Wang DY, Darbre PD (1991) Autocrine production of insulin-like growth factor II using an inducible expression system results in reduced estrogen sensitivity of MCF-7 human breast cancer cells. Cell Growth Differ 2:457-464.
    • (1991) Cell Growth Differ , vol.2 , pp. 457-464
    • Daly, R.J.1    Harris, W.H.2    Wang, D.Y.3    Darbre, P.D.4
  • 12
    • 0028009849 scopus 로고
    • The cell cycle and the retinoblastoma protein family
    • E wen ME (1994) The cell cycle and the retinoblastoma protein family. Cancer Metast Rev 13:45-66.
    • (1994) Cancer Metast Rev , vol.13 , pp. 45-66
    • Ewen, M.E.1
  • 13
    • 0027229136 scopus 로고
    • Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
    • Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J, Livingston DM (1993a) Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell 73:487-97.
    • (1993) Cell , vol.73 , pp. 487-497
    • Ewen, M.E.1    Sluss, H.K.2    Sherr, C.J.3    Matsushime, H.4    Kato, J.5    Livingston, D.M.6
  • 14
    • 0027374766 scopus 로고
    • TGF β inhibition of Cdk4 synthesis is linked to cell cycle arrest
    • Ewen ME, Sluss HK, Whitehouse LL, Livingston DM (1993b) TGF β inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74:1009-20.
    • (1993) Cell , vol.74 , pp. 1009-1020
    • Ewen, M.E.1    Sluss, H.K.2    Whitehouse, L.L.3    Livingston, D.M.4
  • 15
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
    • Gillett C, Fantl V, Smith R, Fisher C, Bartek J, Dickson C, Barnes D, Peters G (1994) Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 54:1812-1817.
    • (1994) Cancer Res , vol.54 , pp. 1812-1817
    • Gillett, C.1    Fantl, V.2    Smith, R.3    Fisher, C.4    Bartek, J.5    Dickson, C.6    Barnes, D.7    Peters, G.8
  • 16
    • 0023110055 scopus 로고
    • Homology probing: Identification of cDNA clones encoding members of the protein-serine kinase family
    • Hanks SK (1987) Homology probing: Identification of cDNA clones encoding members of the protein-serine kinase family. Proc Natl Acad Sci USA 84:388-392.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 388-392
    • Hanks, S.K.1
  • 17
    • 0028168242 scopus 로고
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 18
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 20
    • 0027494864 scopus 로고
    • Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression
    • Jiang W, Kahn SM, Zhou P, Zhang Y-J, Cacace AM, Infante AS, Doi S, Santella RM, Weinstein IB (1993) Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression. Oncogene 8:3447-3457.
    • (1993) Oncogene , vol.8 , pp. 3447-3457
    • Jiang, W.1    Kahn, S.M.2    Zhou, P.3    Zhang, Y.-J.4    Cacace, A.M.5    Infante, A.S.6    Doi, S.7    Santella, R.M.8    Weinstein, I.B.9
  • 21
    • 0026021882 scopus 로고
    • Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product
    • Kaelin WG, Pallas DC, DeCaprio JA, Kaye FJ, Livingston DM (1991) Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell 64:521-532.
    • (1991) Cell , vol.64 , pp. 521-532
    • Kaelin, W.G.1    Pallas, D.C.2    Decaprio, J.A.3    Kaye, F.J.4    Livingston, D.M.5
  • 22
    • 0027288908 scopus 로고
    • Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
    • Kato J-y, Matsushime H, Hiebert SW, Ewen ME, Sherr CJ (1993) Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev 7:331-342.
    • (1993) Genes Dev , vol.7 , pp. 331-342
    • Kato, J.-Y.1    Matsushime, H.2    Hiebert, S.W.3    Ewen, M.E.4    Sherr, C.J.5
  • 23
    • 0028270189 scopus 로고
    • Regulation of cyclin D-dependent kinase 4 (cdk4) by CDK4-activating kinase
    • Kato J-y, Matsuoka M, Strom DK, Sherr CJ (1994) Regulation of cyclin D-dependent kinase 4 (cdk4) by CDK4-activating kinase. Mol Cell Biol 14:2713-2721.
    • (1994) Mol Cell Biol , vol.14 , pp. 2713-2721
    • Kato, J.-Y.1    Matsuoka, M.2    Strom, D.K.3    Sherr, C.J.4
  • 24
    • 0027530449 scopus 로고
    • Redundant cyclin overexpression and gene amplification in breast cancer cells
    • Keyomarsi K, Pardee AB (1993) Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc Natl Acad Sci USA 90:1112-1116.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1112-1116
    • Keyomarsi, K.1    Pardee, A.B.2
  • 26
    • 0026039676 scopus 로고
    • The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
    • Lees JA, Buchkovich KJ, Marshak DR, Anderson CW, Harlow E (1991) The retinoblastoma protein is phosphorylated on multiple sites by human cdc2. EMBO J 10:4279-4290.
    • (1991) EMBO J , vol.10 , pp. 4279-4290
    • Lees, J.A.1    Buchkovich, K.J.2    Marshak, D.R.3    Anderson, C.W.4    Harlow, E.5
  • 27
    • 0025850767 scopus 로고
    • Isolation of three novel human cycling by rescue of G1 cyclin (Cln) function in yeast
    • Lew DJ, Dulic V, Reed SI (1991) Isolation of three novel human cycling by rescue of G1 cyclin (Cln) function in yeast. Cell 66:1197-1206.
    • (1991) Cell , vol.66 , pp. 1197-1206
    • Lew, D.J.1    Dulic, V.2    Reed, S.I.3
  • 28
    • 0026034418 scopus 로고
    • Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase
    • Lin BT-Y, Gruenwald S, Morla AO, Lee W-H, Wang JYJ (1991) Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase. EMBO J 10:857-864.
    • (1991) EMBO J , vol.10 , pp. 857-864
    • Lin, B.T.-Y.1    Gruenwald, S.2    Morla, A.O.3    Lee, W.-H.4    Wang, J.Y.J.5
  • 29
    • 0027976222 scopus 로고
    • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation
    • Lovec H, Sewing A, Lucibello FC, Müller R, Möröy T (1994) Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation Oncogene 9:323-326.
    • (1994) Oncogene , vol.9 , pp. 323-326
    • Lovec, H.1    Sewing, A.2    Lucibello, F.C.3    Müller, R.4    Möröy, T.5
  • 30
    • 0028279059 scopus 로고
    • DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1
    • Lukas J, Müller H, Bartkova J, Spitkovsky D, Kjerulff AA, Jansen-Dürr P, Strauss M, Bartek J (1994) DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1. J Cell Biol 125:625-638.
    • (1994) J Cell Biol , vol.125 , pp. 625-638
    • Lukas, J.1    Müller, H.2    Bartkova, J.3    Spitkovsky, D.4    Kjerulff, A.A.5    Jansen-Dürr, P.6    Strauss, M.7    Bartek, J.8
  • 32
    • 0025819962 scopus 로고
    • Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
    • Matsushime H, Roussel MF, Ashmun RA, Sherr CJ (1991) Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65:701-713.
    • (1991) Cell , vol.65 , pp. 701-713
    • Matsushime, H.1    Roussel, M.F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 35
    • 0028181760 scopus 로고
    • 1 kinase activity for cdk6, a novel cyclin D partner
    • 1 kinase activity for cdk6, a novel cyclin D partner. Mol Cell Biol 14:2077-2086.
    • (1994) Mol Cell Biol , vol.14 , pp. 2077-2086
    • Meyerson, M.1    Harlow, E.2
  • 37
    • 0026640545 scopus 로고
    • Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRAD1/cyclin D1 protooncogene
    • Motokura T, Keyomarsi K, Kronenberg HM, Arnold A (1992) Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRAD1/cyclin D1 protooncogene. J Biol Chem 267:20412-20415.
    • (1992) J Biol Chem , vol.267 , pp. 20412-20415
    • Motokura, T.1    Keyomarsi, K.2    Kronenberg, H.M.3    Arnold, A.4
  • 38
    • 0027730289 scopus 로고
    • Acute effects of growth factors on T-47D breast cancer cell cycle progression
    • Musgrove EA, Sutherland RL (1993) Acute effects of growth factors on T-47D breast cancer cell cycle progression. Eur J Cancer 29A:2273-2279.
    • (1993) Eur J Cancer , vol.29 A , pp. 2273-2279
    • Musgrove, E.A.1    Sutherland, R.L.2
  • 39
    • 0026051580 scopus 로고
    • Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor α, epidermal growth factor receptor, c-fos and c-myc genes
    • Musgrove EA, Lee CSL, Sutherland RL (1991) Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor α, epidermal growth factor receptor, c-fos and c-myc genes. Mol Cell Biol 11:5032-5043.
    • (1991) Mol Cell Biol , vol.11 , pp. 5032-5043
    • Musgrove, E.A.1    Lee, C.S.L.2    Sutherland, R.L.3
  • 40
    • 0027299883 scopus 로고
    • Growth factor, steroid and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression
    • Musgrove EA, Hamilton JA, Lee CSL, Sweeney KJE, Watts CKW, Sutherland RL (1993) Growth factor, steroid and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Mol Cell Biol 13:3577-3587.
    • (1993) Mol Cell Biol , vol.13 , pp. 3577-3587
    • Musgrove, E.A.1    Hamilton, J.A.2    Lee, C.S.L.3    Sweeney, K.J.E.4    Watts, C.K.W.5    Sutherland, R.L.6
  • 45
    • 0023228891 scopus 로고
    • Interactions in vivo upstream of a cell cycle regulated human histone gene
    • Pauli U, Chrysogelos S, Stein J, Stein G, Nick H (1987) Interactions in vivo upstream of a cell cycle regulated human histone gene. Science 236:1308-1311.
    • (1987) Science , vol.236 , pp. 1308-1311
    • Pauli, U.1    Chrysogelos, S.2    Stein, J.3    Stein, G.4    Nick, H.5
  • 49
    • 0028173667 scopus 로고
    • 1/S phase transition by expression of cyclins D1 and E with an inducible system
    • 1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol Cell Biol 14:1669-1679.
    • (1994) Mol Cell Biol , vol.14 , pp. 1669-1679
    • Resnitzky, D.1    Gossen, M.2    Bujard, H.3    Reed, S.I.4
  • 50
    • 0028170806 scopus 로고
    • The retinoblastoma protein: More than a tumor suppressor
    • Riley DJ, Lee EY-HP, Lee W-H (1994) The retinoblastoma protein: More than a tumor suppressor. Annu Rev Cell Biol 10:1-29.
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 1-29
    • Riley, D.J.1    Lee, E.Y.-H.P.2    Lee, W.-H.3
  • 52
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D (1993) A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 53
    • 0028128954 scopus 로고
    • Differential expression and regulation of Cyclin D1 protein in normal and tumor human cells: Association with Cdk4 is required for Cyclin D1 function in G1 progression
    • Tam SW, Theodoras AM, Shay JW, Draetta GF, Pagano M (1994) Differential expression and regulation of Cyclin D1 protein in normal and tumor human cells: Association with Cdk4 is required for Cyclin D1 function in G1 progression. Oncogene 9:2663-2674.
    • (1994) Oncogene , vol.9 , pp. 2663-2674
    • Tam, S.W.1    Theodoras, A.M.2    Shay, J.W.3    Draetta, G.F.4    Pagano, M.5
  • 54
    • 0028363519 scopus 로고
    • P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima H, Hunter T (1994) p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 55
    • 0025885070 scopus 로고
    • Isolation of the human cdk2 gene that encodes the cyclin A- And adenovirus E1A-associated p33 kinase
    • Tsai L-H, Harlow E, Meyerson M (1991) Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature 353:174-177.
    • (1991) Nature , vol.353 , pp. 174-177
    • Tsai, L.-H.1    Harlow, E.2    Meyerson, M.3
  • 56
    • 0027298902 scopus 로고
    • The cdk2 kinase is required for the G1-to-S transition in mammalian cells
    • Tsai LH, Lees E, Faha B, Harlow E, Riabowol K (1993) The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene 8:1593-1602.
    • (1993) Oncogene , vol.8 , pp. 1593-1602
    • Tsai, L.H.1    Lees, E.2    Faha, B.3    Harlow, E.4    Riabowol, K.5
  • 57
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • van den Heuvel S, Harlow E (1993) Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262:2050-2054.
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van den Heuvel, S.1    Harlow, E.2
  • 60
    • 0026699554 scopus 로고
    • Growth regulated expression of D-type cyclin genes in human diploid fibroblasts
    • Won K-A, Xiong Y, Beach D, Gilman MZ (1992) Growth regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc Natl Acad Sci USA 89:9910-9914.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9910-9914
    • Won, K.-A.1    Xiong, Y.2    Beach, D.3    Gilman, M.Z.4
  • 62
    • 0026459047 scopus 로고
    • D type cycling associate with multiple protein kinases and the DNA replication and repair factor PCNA
    • Xiong Y, Zhang H, Beach D (1992) D type cycling associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 71:505-514.
    • (1992) Cell , vol.71 , pp. 505-514
    • Xiong, Y.1    Zhang, H.2    Beach, D.3
  • 64
    • 0027301324 scopus 로고
    • Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation
    • Xiong Y, Zhang H, Beach D (1993b) Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev 7:1572-1583.
    • (1993) Genes Dev , vol.7 , pp. 1572-1583
    • Xiong, Y.1    Zhang, H.2    Beach, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.