What changes drug metabolism in critically ill patients? - II Serum inhibits the metabolism of midazolam in human microsomes

Anaesthesia

Volumn 51, Issue 1, 1996, Pages 11-15

  Park, G R ^a   Miller, E ^a   Navapurkar, V ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Hypnotics; benzodiazepines, midazolam; Intensive care; Metabolism; cytochrome P450

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CYTOCHROME P450; MIDAZOLAM;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICAL ILLNESS; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; HUMAN; LIVER MICROSOME; MALE; SERUM;

AGED; ANTI-ANXIETY AGENTS; CRITICAL ILLNESS; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; INFANT; MALE; MICROSOMES, LIVER; MIDAZOLAM; MIDDLE AGED; MIXED FUNCTION OXYGENASES;

EID: 0029923581     PISSN: 00032409     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2044.1996.tb07646.x     Document Type: Article

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