A practical synthesis of α-acylamino-β-keto-esters: Acylation of alkyl hydrogen (acylamino)malonates via the MgCl2/R3N base system

Tetrahedron Letters

Volumn 37, Issue 19, 1996, Pages 3303-3306

  Krysan, Damian J ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029923546     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00581-3     Document Type: Article

References (7)

1. Noyori, R.; Ikeda, T.; Onkuma, T.; Widhalm, M.; Kitamura, M.; Takaya, H.; Akutagawa, S.; Sayo, N.; Saito, T.; Taketoni, T.; Kumobayashi, H. J. Am. Chem. Soc. 1989, 111, 9134.
2. Schmidt, U.; Griesser, H.; Lieberknecht, A.; Schmidt, J.; Grather, T. Synthesis 1993, 765.
3. Benetti, S.; Romagnoli, R.; De Ris, C.; Spalluto, G.; Zanirato, V. Chem. Rev. 1995, 95, 1065.
4. Clay, R.J.; Collum, T.A.; Karrick, G.L.; Wemple, J. Synthesis 1993, 290.
5. Rathke, M.W.; Cowan, P.J. J. Org. Chem. 1985, 50, 2622.
6. 6N: C, 60.52; H, 6.87; N, 4.15. Found: C, 60.68; H, 6.85; N, 4.05.
7. Fernanbez, A.-M.; Jacob, M.; Gralak, J.; Al-Bayati, V.; Ple, G.; Duhamel, L. Synlett 1995, 431.