Uncoupling of GTP binding from target stimulation by a single mutation in the transducin α subunit

Science

Volumn 271, Issue 5254, 1996, Pages 1413-1416

  Mittal, Rohit ^a   Erickson, Jon W ^a   Cerione, Richard A ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYCLIC GMP PHOSPHODIESTERASE; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; MUTANT PROTEIN; PROTEIN SUBUNIT; RHODOPSIN; TRANSDUCIN;

ALPHA CHAIN; ARTICLE; CONFORMATIONAL TRANSITION; PRIORITY JOURNAL;

EID: 0029923266     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.271.5254.1413     Document Type: Article

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22. We thank J. V. Platko for discussions and molecular biological advice and C. Westmiller for technical assistance. Supported by grants from NIH