NE-induced contraction, α1-adrenergic receptors, and Ins(1,4,5)P3 responses in cerebral arteries

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 270, Issue 3 39-3, 1996, Pages

  Longo, Lawrence D ^a   Ueno, Nobumi ^b   Zhao, Yu ^a   Zhang, Lubo ^a   Pearce, William J ^a  

^a LOMA LINDA UNIVERSITY   (United States)

^b NONE

Author keywords

alpha adrenoreceptors; cerebral flood flow; inositol phosphates; sympathetic nervous system

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; NORADRENALIN; POTASSIUM ION; PRAZOSIN;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; BRAIN ARTERY; BRAIN BLOOD FLOW; DISSOCIATION CONSTANT; DOSE RESPONSE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; SHEEP;

EID: 0029923105     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.3.h915     Document Type: Article

References (50)

1. Alexander, E., III, and A. H. Friedman. The identification of adrenergic receptors in human pial membranes. Neurosurgery 27: 52-59, 1990.
2. 2-Adrenoceptors mediate norepinephrine constriction of porcine pial veins. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H1907-H1910, 1992.
3. 1 receptors associated with vascular smooth muscle: evidence from functional and ligand binding studies. Life Sci. 41: 663-673, 1987.
4. Berridge, M. J. Inositol trisphosphate and diacylglycerol two interacting second messengers. Annu. Rev. Biochem. 56: 159-193, 1987.
5. Berridge, M. J., and R. F. Irvine. Inositol phosphates and cell signalling. Nature Lond. 341: 197-205, 1989.
6. Bevan, J. A. A comparison of the contractile responses of the rabbit basilar and pulmonary arteries to sympathomimetic agonists: further evidence for variation in vascular adrenoceptor characteristics. J. Pharmacol. Exp. Ther. 216: 83-89, 1981.
7. Bevan, J. A., R. D. Bevan, and S. M. Shreeve. Variable receptor affinity hypothesis. FASEB J. 3: 1696-1704, 1989.
8. Bevan, J. A., J. Duckworth, I. Laher, M. A. Oriowo, G. A. McPherson, and R. D. Bevan. Sympathetic control of cerebral arteries: specialization in receptor type, reserve, affinity, and distribution. FASEB J. 1: 193-198, 1987.
9. Bevan, J. A., M. A. Oriowo, and R. D. Bevan. Physiological variation in α-adrenoceptor-mediated arterial sensitivity: relation to agonist affinity. Science Wash DC 234: 196-197, 1986.
10. Bevan, R. D. Trophic effects of peripheral adrenergic nerves on vascular structure. Hypertension Dallas 6, Suppl. III: III-19 111-26, 1984.
11. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254, 1976.
12. Brading, A. F., and A. W. Jones. Distribution and kinetics of CoEDTA in smooth muscle, and its use as an extracellular marker. J. Physiol. Lond. 200: 387-401, 1969.
13. 2-adrenoreceptors in newborn pigs. J. Cereb. Blood Flow Metab. 7: 184-188, 1987.
14. Capponi, A. M., M. F. Rossier, and M. B. Vallotton. Production of inositol trisphosphate isomers and release of intracellular calcium in cultured aortic vascular smooth muscle cells. J. Cardiovasc. Pharmacol. 12, Suppl. 5: S92-S95, 1988.
15. Edvinsson, L., and E. T. MacKenzie. Amine mechanisms in the cerebral circulation. Pharmacol. Rev. 28: 275-353, 1976.
16. Elliott, C. F., and W. J. Pearce. Effects of maturation on cell water, protein and DNA content in ovine cerebral arteries. J. Appl. Physiol. 79: 831-837, 1995.
17. Elliott, S. R., and W. J. Pearce. Effects of maturation on α-adrenergic receptor affinity and occupancy in small cerebral arteries. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H757-H763, 1994.
18. Estrada, C., E. Hamel, and D. N. Krause. Biochemical evidence for cholinergic innervation of intracerebral blood vessels. Brain Res. 266: 261-270, 1983.
19. Estrada, C., and D. N. Krause. Muscarinic cholinergic receptor sites in cerebral blood vessels. J. Pharmacol. Exp. Ther. 221: 85-90, 1982.
20. Estrada, C., D. Triguero, J. Munoz, and A. Sureda. Acetylcholinesterase-containing fibers and choline acetyltransferase activity in isolated cerebral microvessels from goats. Brain Res. 453 275-280, 1988.
21. Gaw, A. J., and R. M. Wadsworth. Pharmacological characterization of postjunctional α-adrenoceptors in cerebral arteries from the sheep. Br. J. Pharmacol. 98: 741-746, 1989.
22. Hartman, B. K. The innervation of cerebral blood vessels by central noradrenergic neurons. In: Frontiers in Catecholamine Research, edited by E. Usdin and S. Snyder. New York: Pergamon, 1973, p. 91-96.
23. Hashimoto, T., M. Hirata, T. Itoh, Y. Kanmura, and H. Kuriyama. Inositol 1,4,5-trisphosphate activates pharmacomechanical coupling in smooth muscle of the rabbit mesenteric artery. J. Physiol. Lond. 370: 605-618, 1986.
24. Hayashi, S., M. K. Park, and T. J. Kuehl. Higher sensitivity of cerebral arteries isolated from premature and newborn baboons to adrenergic and cholinergic stimulation. Life Sci. 35: 253-260, 1984.
25. Heistad, D. D., and M. L. Marcus. Evidence that neural mechanisms do not have important effects on cerebral blood flow. Circ. Res. 42: 295-302, 1978.
26. Ḧgestätt, E. D., and K.-E. Andersson. On the postjunctional α-adrenoreceptors in rat cerebral and mesenteric arteries. J Auton. Pharmacol. 4: 161-173, 1984.
27. Kenakin, T. P. The classification of drugs and drug receptors in isolated tissues. Pharmacol. Rev. 36: 165-222, 1984.
28. Kobayashi, H., A. Cazzaniga, P. F. Spano, and M. Trabucchi. Ontogenesis of α- and β-receptors located on cerebral microvessels. Brain Res. 242: 358-360, 1982.
29. Kobayashi, H., A. Wada, F. Izumi, M. S. Magnoni, and M. Trabucchi. α-Adrenergic receptors in cerebral microvessels of normotensive and spontaneously hypertensive rats. Circ. Res. 56: 402-409, 1985.
30. Laher, I., and J. A. Bevan. Alpha-adrenoceptor number limits response of some rabbit arteries to norepinephrine. J. Pharmacol. Exp. Ther. 233: 290-297, 1985.
31. McCalden, T. A. Sympathetic control of the cerebral circulation. J. Auton. Pharmacol. 1: 421-431. 1981.
32. McCalden, T. A., and J. A. Bevan. Sources of activator calcium in rabbit basilar artery. Am. J. Physiol. 241 (Heart Circ. Physiol. 10): H129-H133, 1981.
33. 2+. Pharmacol. Rev. 40: 87-119, 1988.
34. Moore, S. A., P. H. Figard, A. A. Spector, and M. N. Hart. Brain microvessels produce 12-hydroxyeicosatetraenoic acid. J. Neurochem. 53: 376-382, 1989.
35. O'Neill, C., C. J. Fowler, J. O. Marcusson, and B. Winblad. Adrenergic, serotoninergic, histaminergic, and imipramine binding sites in post-mortal human cerebral microvessel preparations. J. Neural Transm. 73: 177-189, 1988.
36. Oriowo, M. A., J. A. Bevan, and R. D. Bevan. Variation in sensitivity of alpha adrenoceptor-mediated contraction of the vascular smooth muscle of rabbit elastic and muscular arteries is related to receptor affinity. J. Pharmacol. Exp Ther. 241: 239-244, 1987.
37. 1-adrenoceptor subtypes in rabbit thoracic aorta. Br J. Pharmacol. 108: 1071-1076, 1993.
38. Pearce, W. J., S. Ashwal, and J. Cuevas. Direct effects of graded hypoxia on intact and denuded rabbit cranial arteries. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H824-H833, 1989.
39. Pearce, W. J., A. D. Hull, D. M. Long, and L. D. Longo. Developmental changes in ovine cerebral artery composition and reactivity. Am. J. Physiol. 261 (Regulatory Integrative Comp. Physiol. 30): R458-R465, 1991.
40. Peroutka, S. J., M. A. Moskowitz, J. F. Reinhard, Jr., and S. H. Snyder. Neurotransmitter receptor binding in bovine cerebral microvessels. Science Wash. DC 208: 610-612, 1980.
41. Piascik, M. T., J. W. Kusiak, J. Pitha, B. T. Butler, H. T. Le, and M. Babich. Alkylation of alpha-1 receptors with a chemically reactive analog of prazosin reveals low affinity sites for norepinephrine in rabbit aorta. J. Pharmacol. Exp. Ther. 246: 1001-1011, 1988.
42. Reimer, R. K., A. Goldfien, and J. M. Roberts. Rabbit myometrial adrenergic sensitivity is increased by estrogen but is independent of changes in alpha adrenoceptor concentration. J. Pharmacol. Exp. Ther. 240: 44-50, 1987.
43. 1-adrenoceptor subtypes and noradrenaline-induced contraction in rat portal vein smooth muscle. Br. J. Pharmacol. 110: 207-212, 1993.
44. Shi, A. G., C. Y. Kwan, and E. E. Daniel. Relation between density (maximum binding) of alpha adrenoceptor binding sites and contractile response in four canine vascular tissues. J. Pharmacol. Exp. Ther. 250: 1119-1124, 1989.
45. Toda, N. Alpha adrenergic receptor subtypes in human, monkey and dog cerebral arteries. J. Pharmacol. Exp. Ther. 226: 861-868, 1983.
46. Traystman, R. J., and C. E. Rapela. Effect of sympathetic nerve stimulation on cerebral and cephalic blood flow in dogs. Circ. Res. 36: 620-630, 1975.
47. U'Prichard, D. C., D. A. Greenberg, and S. H. Snyder. Binding characteristics of a radiolabeled agonist and antagonist at central nervous system alpha noradrenergic receptors. Mol. Pharmacol. 13: 454-473, 1977.
48. Van Riper, D. A., and J. A. Bevan. Selective variation of agonist and neurally mediated vasoconstriction with rabbit middle cerebral artery branch order. J. Pharmacol. Exp. Ther. 257: 879-886, 1991.
49. Wagerle, L. C., C. D. Kurth, and R. A. Roth. Sympathetic reactivity of cerebral arteries in developing fetal lamb and adult sheep. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H1432-H1438, 1990.
50. Zhang, L., and I. L. O. Buxton. Muscarinic receptors in canine colonic circular smooth muscle. II. Signal transduction pathways. Mol. Pharmacol. 40: 952-959, 1991.