Putative effect of silymarin on sawfly (Arge pullata)-induced hepatotoxicosis in sheep

Veterinary and Human Toxicology

Volumn 38, Issue 2, 1996, Pages 89-91

  Thamsborg, Stig M ^a   Jøegensen, Rolf J ^a   Brummerstedt, Erik ^a   Bjerregard, Jytte ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; OCTAPEPTIDE; PENICILLIN G; PROCAINE PENICILLIN; PROTEIN; SILYMARIN; TOXIN; UREA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FLY; INTRAVENOUS DRUG ADMINISTRATION; LARVA; LIVER BIOPSY; LIVER TOXICITY; NONHUMAN; SHEEP;

ANIMALS; BIOPSY, NEEDLE; DRUG SYNERGISM; GLUCOSE; HEMATOCRIT; HEMOGLOBINS; HYMENOPTERA; LARVA; LEUKOCYTE COUNT; LIVER; LIVER DISEASES; ORGAN SIZE; PENICILLINS; SHEEP; SHEEP DISEASES; SILYMARIN;

ANIMALIA; ARGE; OVIS ARIES; SILYBUM MARIANUM;

EID: 0029922961     PISSN: 01456296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Thamsborg SM, Jørgensen RJ, Brummerstedt E: Sawfly poisoning in sheep and goats. Vet Rec 121: 253-255, 1987.
2. Karinan R, Oelrichs PB, Thamsborg SM et al: Identification of the octapeptide lophyrotomin in the European birch sawfly (Arge pullata). Toxicon 126: 224-226, 1988.
3. McKenzie RA, Dunster PJ, Twist JO et al: The toxicity of sawfly larvae (Lophyrotoma interrupts) to cattle. Queensland Department of Primary Industries, Bulletin QB85001, 1985.
4. Oelrichs PB: Sawfly poisoning of cattle. Queensland Agri J 108: 110-112, 1982.
5. Parish RC, Doering PL: Treatment of Amanita mushroom poisoning: A review. Vet Hum Toxicol 28: 318-321, 1986.
6. Vojtisek B, Hronova B, Hamrik J et al: Ostropestrec mariansky (Silybum marianum L, Gaertn) v krmne davce ketoznich krav (milk thistle [Silybum marianum L, Gaertn] in feed rations administered to ketotic cons) (English abstract). Vet Med (Praha) 36: 321-330, 1991.
7. Floersheim CL, Eberhard M, Tschumi P et al: Effects of penicillin and silymarin on liver enzymes and blood clotting factors in dogs given a boiled preparation of Amanita phalloides. Toxicol Appl Pharm 46: 455-462, 1978.
8. Harvey RB, Lovering SL, Bailey EM et al: The influence of multiple liver biopsies on hematologic and serum biochemical values of sheep. Cornell Vet 74: 322-330, 1984.
9. Oleachea FV, Thamsborg SM, Christensen NØ et al: Interference with sawfly (Arge pullata) poisoning in Fasciola hepatica-infected lambs. J Comp Path 104: 419-433, 1991.
10. Leber HW, Knauff S: Influence of silymarin on drug metabolizing enzymes in rat and man. Drug Res 26: 1603-1605, 1976.
11. Hapke H: Toxikologie fur Veterinarmediziner Ferdinand Enke Verlag, Stuttgart: 59, 1988.
12. Finco DR: Kidney function. In Kaneko JR ed: Clinical Biochemistry of Domestic Animals, 4th ed. Academic Press, New York: 496-542, 1989.
13. Kallet A, Sousa C, Spangler W: Mushroom (Amanita phalloides) toxicity in dogs. California Vet 42: 9-11, 1988.
14. Brummerstedt E, Kristensen A, Nielsen R et al: Death in puppies following uptake of sawfly larvae (in Danish). Dansk Vet Tidsskrift 70: 758-760, 1987.