Aberrant regulation of cytokines in HIV-1 TAT72-transgenic mice

Journal of Immunology

Volumn 156, Issue 10, 1996, Pages 3631-3637

  Garza Jr , Hildegardo H ^a   Prakash, Om ^b   Carr, Daniel J J ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^b OCHSNER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; VIRUS RNA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION REGULATION; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOREGULATION; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; VIRUS DNA CELL DNA INTERACTION;

ANIMALS; BASE SEQUENCE; CYTOKINES; GENE PRODUCTS, TAT; HIV-1; IMMUNOPHENOTYPING; INTERLEUKIN-2; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PROTEIN BIOSYNTHESIS; RNA, MESSENGER;

EID: 0029922931     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Cullen, B. R. 1992. Mechanism of action of regulatory proteins encoded by complex retroviruses. Microbiol Rev 56:375.
2. Kato, H., H Sumimoto, P. Pognonec, C. H Chen, C. A Rosen, and R. G. Roeder 1992. HIV-1 tat acts as a processivity factor in vitro in conjunction with cellular elongation factors Genes Dev. 6.655.
3. Carroll, R., B. M Peterlin, and D. Derse. 1992. Inhibition of human immunodeficiency virus type 1 tat by coexpression of heterologous trans activators. J. Virol. 66:2000.
4. Taylor, J. P., M Kundu, and K. Khalili. 1993. TAR-independent activation of HIV-1 requires the activation domain but not the RNA-binding domain of tat. Virology 195:780
5. 5-integrin to the basic domain of the HIV tat protein and vitronectin. J. Cell Biol 121.461.
6. Howcroft, T. K., K. Strebel, M. A. Martin, and D. S. Singer 1993. Repression of MHC class I gene promoter activity by two-exon tat of HIV Science 260:1320.
7. 72-transgenic mice: effects of morphine on cell-mediated immunity. Int J Immunopharmacol. 16:1061
8. Zinkernagel, R. M., and A. Althage. 1977. Antiviral protection by virus immune cytocoxic T lymphocytes, infected target cells are lysed before infectious virus progeny is assembled. J. Exp. Med 145:644
9. Herberman, R. B., and J. R. Ortaldo 1981. Natural killer cells: their role in defenses against disease. Science 214:24.
10. Frankel, A. D., and C. O. Pabo. 1988. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 55:1189
11. Robinet, E , M. Kamoun, F Farace, and S. Chouaib. 1992. Interleukin-4 differentially regulates interleukin-2-mediated and CD2-mediated induction of human lymphokine-activated killer effectors. Eur J. Immunol 22:2861.
12. Carr, D. J. J., S. Mayo, B. M. Gebhardt, and P Porter 1994. Central α-adrenergic involvement in morphine-mediated suppression of splenic natural killer activity. J Neuroimmunol 53:53.
13. Smith, K. A. 1988. Interleukin-2: inception, impact, and implication. Science 240:1169.
14. D'Angeac, A. D., J. Dornand, X. Emonds-Alt, P. Jullien, J. A. Garcia-Sanz, and F. Erard. 1991. Transforming growth factor-β type 1 (TGF-β type 1) down-regulates interleukin-2 production and up-regulates interleukin-2 receptor expression in a thymoma cell line. J. Cell Physiol. 147:460.
15. H2 switch is a critical step in the etiology of HIV infection. Immunol. Today 14:107.
16. H2 cytokine production by peripheral blood mononuclear cells from HIV-1 infected patients. AIDS 8:757.
17. Gerez, L., G. Arad, S. Efrat, M. Ketzmel, and R Kaempfer 1995 Post-transcriptional regulation of human interleukin-2 gene expression at processing of precursor transcripts. J. Biol. Chem. 270:19569.
18. Brady, H. J. M., D J Abraham, D J. Pennington, C. G. Miles, S Jenkins, and E. A. Dzierzak. 1995. Altered cytokine expression in T lymphocytes from human immunodeficiency virus TAT transgenic mice. J. Virol 69:7622.