A brain uptake study of [1-11C]hexanoate in the mouse: The effect of hypoxia, starvation and substrate competition

Annals of Nuclear Medicine

Volumn 10, Issue 2, 1996, Pages 265-270

  Ishiwata, Kiichi ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Brain; Oxidative metabolism; PET; 1 11c hexanoate; oxidation

Indexed keywords

CARBON 11; HEXANOIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BRAIN BLOOD FLOW; BRAIN HYPOXIA; BRAIN OXYGEN CONSUMPTION; BRAIN SCINTISCANNING; DRUG CLEARANCE; DRUG UPTAKE; IMAGE ANALYSIS; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; STARVATION; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; DEOXYGLUCOSE; HEXANOIC ACIDS; HYPOXIA, BRAIN; INJECTIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED STRAINS; SODIUM ACETATE; TOMOGRAPHY, EMISSION-COMPUTED; TRITIUM;

EID: 0029922784     PISSN: 09147187     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03165404     Document Type: Article

References (3)

1. Blomqvist G, Seitz RJ, Sjögren I, Halldin C, Slone-Elander S, Widen L, et al. Regional cerebral oxidative and total glucose consumption during rest and activation studied with positron emission tomography. Acta Physiol Scand 151: 29-43, 1994.
2. Fukuyama H, Ogawa M, Yamauchi H, Yamaguchi S, Kimura J, Yonekura Y, et al. Altered cerebral energy metabolism in Alzheimer's disease: a PET study. J Nucl Med 35: 1-6, 1994.
3. Lear JL, Ackerman RF. Comparison of cerebral glucose metabolic rates measured with fluorodeoxyglucose and glucose labeled in the 1,2,3-4, and 6 positions using double label quantitative digital autoradiography. J Cereb Blood Flow Metab 8: 575-585, 1988.