Delayed effects and induction of genetic instability by radiation

Journal of Toxicological Sciences

Volumn 21, Issue 1, 1996, Pages 61-63

  Niwa, Ohtsura ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGENESIS; CONFERENCE PAPER; DNA DAMAGE; GENE MUTATION; GERM LINE; MUTATION; RADIATION DOSE; RADIATION EXPOSURE;

EID: 0029922279     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.21.61     Document Type: Conference Paper

References (15)

1. Armitage, P. and Doll, R. (1954) : The age distribution of cancer and a multistage theory of carcinogenesis. Br. J. Cancer, 8, 1-12.
2. Fan, Y. et al. (1995) : Dose-response of a radiation induction of a germline mutation at a hypervariable mouse minisatellite locus. Int. J. Radiat. Biol., 68, 177-183.
3. Fearon, E.R. and Vogelstein, B. (1990) : A genetic model for colorectal tumorigenesis. Cell, 61, 759-767.
4. Kamiya, K. et al. (1995) : Evidence that carcinogenesis involves an imbalance between epigenetic high-frequency initiation and suppression of promotion. Proc. Natl. Acad Sci. USA, 92, 1332-1336.
5. Kelly, R. et al. (1989) : Characterization of a highly unstable mouse minisatellite locus : evidence for somatic mutation during early development. Genomics, 5, 844-856.
6. Kennedy, A. R. et al. (1980) : Relationship between X-ray exposure and malignant transformation in C3H10T1/2 cells. Proc. Natl. Acad. Sci. USA. 77, 7262-7266.
7. Mitani, K. et al. (1990) : A GGCAGG motif in minisatellites affecting their germline instability. J. Biol. Chem., 265, 15203-15210.
8. Monkton, D. G. et al. (1994) : Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism. Nature Genet., 8, 162-170.
9. Niwa, O. et al. . Association of minisatellite instability with c-myc amplification and K-ras mutation in methylcholanthrene-induced mouse sarcomas. Cancer Res., in press.
10. Nomura, T. (1982) : Parental exposure to X-rays and chemicals induces heritable tumors and anormalies in mice. Nature, 296, 575-577.
11. Preston, D. L. et al. (1994) : Cancer incidence in atomic bomb survivors. Part III : leukemia, lymphoma and multiple myeloma, 1950-1987. Radiat. Res., 137, S68-S97.
12. Russell, W. L. and Kelly, E. M. (1982) : Mutation frequencies in male mice and the extimation of genetic hazards of radiation in man. Proc. Natl. Acad. Sci. USA, 79, 542-544.
13. Sadamoto, S. et al. (1994) : Radiation induction of germline mutation at a hypervariable mouse minisatellite locus. Int. J. Radiat. Biol., 65, 549-557.
14. Shimizu, Y. et al. (1990) : Studies of the mortality of A-bomb survivors. Radiat. Res., 121, 120-141.
15. Thompson, D. E. et al. (1994) : Cancer incidence in atomic bomb survivors. Part II : Solid tumors, 1958-1987. Radiat. Res., 137. S17-S67.