Biotransformation of lignans: Metabolism of (+)-yangabin in spodoptera litura

Natural Product Letters

Volumn 8, Issue 2, 1996, Pages 87-88

  Miyazawa, Mitsuo ^a   Kasahara, Hiroyuki ^a   Kameoka, Hiromu ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

(+) de 4 O methylyangabin 4 O D glucoside; (+) yangabin; Biotransformation; De O methylation; Glucoside conjugation; Lignan; Noctuidae; Spodoptera litura

Indexed keywords

LIGNAN; NEOLIGNAN;

ARTICLE; BIOTRANSFORMATION; DEMETHYLATION; DRUG TRANSFORMATION; LARVA; LEPIDOPTERA;

EID: 0029922267     PISSN: 10575634     EISSN: None     Source Type: Journal    
DOI: 10.1080/10575639608043245     Document Type: Article

References (8)

1. Russel, G. B., Singh, P. and Fenmore, P. G. (1976) Aust. J. Biol. Sci. 29, 99.
2. Gonzalez-Coloma, A., Escoubuas, P., Mizutani, J. and Lajide, L. (1994) Phytochemistry 35, 607.
3. Kamikado, T., Chan, C.-F., Murakoshi, S., Sakurai, A. and Tamura, S. (1975) Agr. Biol. Chem., 39, 833.
4. Miyazawa, M., Kasahara, H. and Kameoka, M. (1995) Phytochemistry 39, 1027.
5. Miyazawa, M., Kasahara, H. and Kameoka, H. (1993) Phytochemistry 32, 1421.
6. Miyazawa, M., Kasahara, H. and Kameoka, H. (1993) Phytochemistry 34, 1501.
7. 2 extract (270 mg) of 1 (160 mg) administered-larvae faeces was subjected to silica gel CC to give novel metabolite 2 (5 mg).
8. 3) δ 54.3 (C-5), 54.5 (C-1), 56.2 (OMe-3″, 5″), 56.4 (OMe-3′, 5′), 60.8 (OMe-4″), 62.5 (glu-C-6), 70.3 (glu-C-4), 71.9 (C-8), 72.1 (C-4), 74.2 (glu-C-2), 76.0 (glu-C-5), 76.6 (glu-C-3), 85.7 (C-6), 85.9 (C-2), 102.8 (glu-C-1), 102.8 (C-2″, 6″), 106.3 (C-2′, 6′), 134.4 (C-1″), 136.6 (C-1″), 137.6 (C-4″), 138.7 (C-4′), 152.9 (C-3′, 5′), 153.5 (C-3″, 5″).