Effect of alteration in the extracellular potassium and calcium on field-stimulated relaxation of the rabbit corpus cavernosum

General Pharmacology

Volumn 27, Issue 2, 1996, Pages 375-378

  Saito, Masahiko ^a,b   Broderick, Gregory ^a,b   Wein, Alan J ^a,b   Levin, Robert M ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

calcium; corpus cavernosum; impotence; potassium; rabbit; sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETHANECHOL; CALCIUM; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS CAVERNOSUM; ELECTROSTIMULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SARCOPLASMIC RETICULUM; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE RELAXATION;

EID: 0029922068     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-3623(95)02029-2     Document Type: Article

References (23)

1. Adams D. J., Barakh J., Luskey R. and Van Breeman C. (1989) Ion channels and regulation of intracellular calcium in vascular endothelial cells. FASEB 3, 2389-2400.
2. Ashley C. C. and Caldwell P. C. (1974) Calcium movements in relation to contraction. Biochem. Soc. Symp. 39, 29-50.
3. Baker P. F. (1986) The sodium-calcium exchange system. In: Calcium and the Cell (Ciba Foundation Symposium 122). (Edited by Evered D. and Whelan J.) pp. 73-92. John Wiley and Sons, Chichester.
4. Batra S., Sjogren C., Andersson K.-E. and Fovaeus M. (1987) Source of calcium for contractions induced by depolarization and muscarinic receptor stimulation in rabbit urinary bladder. Acta Physiol. Scand. 130, 545-551.
5. Benson G. S., McConnell J., Lipschulze L. I., Corriere J. N. and Wood, J. (1980) Neuromorphology and neuropharmacology of human penis. J. Clin. Invest. 65, 506-513.
6. 2+ dependence of the release of nitric oxide from non-adrenergic and non-cholinergic nerves. Br. J. Pharmac. 110, 1329-1334.
7. Broderick G., Hypolite J. A. and Levin R. M. (1991). In-vitro contractile response of the rabbit corpus cavernosa to field stimulation and autonomic agonists and antagonists: a qualitative study. Neurourol. Urodyn. 10, 507-515.
8. Carafoli E., Zurini M. and Benaim G. (1986) The calcium pump of the plasma membrane. In: Calcium and the Cell (Ciba Foundation Symposium 122). (Edited by Evered D. and Whelan J.) pp. 58-72. John Wiley and Sons, Chichester.
9. Cetiner M. and Bennett M. R. (1993) Nitric oxide modulation of calcium-activated potassium channels in postganglionic neurones of avian cultured ciliary ganglia. Br. J. Pharmac. 110, 995-1002.
10. Hypolite J. A., Broderick G. A. and Levin R. M. (1993) Correlation of contractile function of the rabbit corpus cavernosum with NADH fluorescence. Pharmacology 46, 353-361.
11. Ito Y. and Itoh T. (1984) The role of stored calcium in contraction of cat tracheal smooth muscle produced by electrical stimulation, acetylcholine and high K+. Br. J. Pharmac. 83, 667-676.
12. Karaki H. and Weiss G. B. (1988) Minireview. Calcium release in smooth muscle. Life Sci. 42, 111-122.
13. 2+/calmodulin-dependent nitric oxide synthase and a soluble guanylyl cyclase in vertebrate photoreceptor cells. Embo. J. 13, 3312-3320.
14. Levin R. M., Hypolite J. A. and Broderick G. A. (1994) Comparative studies on intracellular calcium and NADH fluorescence of the rabbit corpus cavernosum. Neurourol. Urodyn. 13, 609-618.
15. Levin R. M., Tong Y-T., Hypolite J. A. and Broderick G. (1991) Correlation of calcium movements with the contractile response of the rabbit corpus cavernosum using Fura-2 calcium fluorescence. Int. J. Impotence Res. 3, 141-153.
16. Mayer B. (1994) Nitric oxide/cyclic GMP-mediated signal transduction. Ann. NY Acad. Sci. 733, 357-364.
17. Peach M. J., Singer H. A., Izzo M. J. Jr. and Loeb A. L. (1984) Role of calcium in endothelium dependent relaxation of arterial smooth muscle. Am. J. Cardiol 48, 35A-43A.
18. Ryan U. S. Endothelium as a transducing surface. J. Mol. Cell Cardiol. 1(Suppl.): 85-90, 1989.
19. Saenz de Tejada I., Blanco R., Goldstein I., Azadzoi K., de las Morenas A., Krane R. J. and Cohen R. A. (1988a) Cholinergic neutrotransmission in human corpus cavernosum. I. Responses of isolated tissue. Am. J. Physiol. 254, H459-H467.
20. Saenz de Tejada I., Goldstein I. and Krane R. J. (1988b) Local control of penile erection. Urol. Clin. North Am. 15, 9-25.
21. Saito M., Longhurst P. A., Wein A. J. and Levin R. M. (1993) Effect of potassium on the contractile response of the rat detrusor muscle to field stimulation at increasing calcium concentration. Gen. Pharmac. 24, 89-93.
22. Tong Y-T., Broderick G., Hypolite J. A. and Levin R. M. (1992) Correlations of purinergic and adrenergic functions in rabbit corporal cavernosal tissue. Pharmocology, 45, 241-249.
23. Ward S. M., Shuttleworth C. W. and Kenyon J. L. (1994) Dorsal root ganglion neurons of embryonic chicks contain nitric oxide synthase and respond to nitric oxide. Brain Res. 648, 249-258.