Renal denervation prevents sodium retention and hypertension in salt-sensitive rabbits with genetic baroreflex impairment

Clinical Science

Volumn 90, Issue 4, 1996, Pages 287-293

  Weinstock, Marta ^a   Gorodetsky, Elena ^a   Kalman, Ronald ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Cardiopulmonary baroreceptors; Conscious rabbits; High salt intake; Plasma renin activity; Renal sympathetic nerves; Sodium excretion

Indexed keywords

POTASSIUM; RENIN; SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; FEMALE; GENETIC DISORDER; HEART RATE; HEMATOCRIT; HYPERTENSION; KIDNEY DENERVATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PLASMA RENIN ACTIVITY; POTASSIUM BLOOD LEVEL; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RABBIT; SALT LOADING; SODIUM BALANCE; SODIUM BLOOD LEVEL; SODIUM RETENTION; WEIGHT GAIN;

EID: 0029922041     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0900287     Document Type: Article

References (30)

1. DiBona GF. Neural regulation of renal tubular sodium reabsorption and renin secretion. Fed Proc 1985; 44: 2816-22.
2. Rydstedt LL, Williams GH, Hollenberg NK. Renal and endocrine response to saline infusion in essential hypertension. Hypertension 1986; 8: 217-22.
3. Hollenberg NK, Moore T, Shoback D, Redgrave J, Rabinowe S, Williams GH. Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II. Am J Med 1986; 81: 412-18
4. Rabinowe SL, Redgrave JE, Shoback DM, Podolsky S, Hollenberg NK, Williams GH. Renin suppression by saline is blunted in nonmodulating essential hypertension. Hypertension 1987; 10: 404-8.
5. Campese VM, Parise M, Karubian F, Bigazzi R. Abnormal renal hemodynamics in black salt-sensitive patients with hypertension. Hypertension 1991; 18: 805-12.
6. Skrabal F, Herholz H, Neumayr M, et al. Salt sensitivity in humans is linked to enhanced sympathetic responsiveness and enhanced proximal tubular reabsorption. Hypertension 1984; 4: 152-8.
7. Weinstock M, Borosh M. Low baroreflex sensitivity predisposes to salt-sensitive hypertension in the rabbit. Am J Physiol 1993; 264: H505-11.
8. Weinstock M, Weksler-Zangen S, Schorer-Apelbaum D. Genetic factors involved in the determination of baroreceptor-heart rate sensitivity. J Hypertens 1986; 4: (Suppl. 6); S290-2.
9. Weinstock M, Borosh M, Kafri O, Kaczmarczyk G. Relationship between baroreflex sensitivity, renin suppression and natriuresis in salt-sensitive rabbits. J Hypertens 1991; 9: 799-804.
10. Razin M, Borosh M, Weinstock M. Rabbits with a genetic impairment in baroreflex sensitivity show abnormal renal haemodynamics and proximal tubular sodium reabsorption in response to a saline infusion. J Hypertens 1993; II: 799-804.
11. Clement DL, Pelletier C, Shepherd JT. Role of vagal afferents in the control of renal sympathetic nerve activity in the rabbit. Circ Res 1972; 31: 824-30.
12. Seeley EW, Moore TJ, Shoback D, et al. Angiotensin-mediated renin suppression is altered in non-modulating hypertension. Hypertension 1989; 13: 31-7.
13. Weinstock M, Korner PI, Head GA, Dorward PK. Differentiation of cardiac baroreflex properties by cuff and drug methods in rabbit strains. Am J Physiol 1988; 255: R654-64.
14. Kent BB, Drane JW, Blumenstein B, Manning JW. A mathematical model to assess changes in the baroreflex. Cardiology 1972; 57: 295-310.
15. Marquardt DW. An algorithm for least-squares estimates of non-linear parameters. SIAM J Appl Math 1963; II: 431-41.
16. Ryuzaki M, Suzuki H, Kumagai K, et al. Role of vasopressin in salt-induced hypertension in barodenervated uninephrectomized rabbits. Hypertension 1991; 17: 1085-91.
17. Hayashi K, Matsumura Y, Yoshida Y, Suzuki Y, Morimoto S. The role of endogenous angiotensin II in antidiuresis and norepinephrine overflow induced by stimulation of renal nerves in anesthetized dogs. J Cardiovasc Pharmacol 1991; 17: 807-13.
18. Kumagai K, Suzuki H, Ichikawa M, et al. Nitric oxide increases renal blood flow by interacting with the sympathetic nervous system. Hypertension 1994; 24: 220-6.
19. Krieger JE, Liard J-F, Cowley AW. Hemodynamics, fluid volume, and hormonal responses to chronic high-salt intake in dogs. Am J Physiol 1990; 259: H1629-36.
20. Guyton AC. Kidneys and fluids in pressure regulation Small volumes but large pressure changes. Hypertension 1992; 19 (Suppl. I): 12-8.
21. Blaustein MP, Hamlyn JM. Pathogenesis of essential hypertension - a link between dietary salt and high blood pressure. Hypertension 1991; 18: S184-95.
22. Widdicombe JG. Respiratory reflexes in man and other mammalian species. Clin Sci 1961; 21: 163-70.
23. Dorward PK, Riedel W, Burke SL, Gipps J, Korner P. The renal sympathetic baroreflex in the rabbit. Arterial and cardiac baroreceptor influences, resetting, and effect of anesthesia. Circ Res 1985; 57: 618-33.
24. Kurkus J, Sadowski J, Gellert R, Krus S. Influence of renal denervation on urine concentration in awake and anaesthetized dogs. Eur J Clin Invest 1980; 10: 463-7.
25. Peterson TV, Benjamin BA, Hurst NL. Renal nerves and renal responses to volume expansion in conscious monkeys. Am J Physiol 1988; 255: R388-94.
26. Greenberg SG, Tershner S, Osborn JL. Neurogenic regulation of rate of achieving sodium balance after increasing sodium intake. Am J Physiol 1991; 261: F300-7.
27. Navar LG, Mitchell KD. Contribution of the tuberoglomerular feedback mechanism to sodium homeostasis and interaction with the renin-angiotensin system. Acta Physiol Scand 1990; 139: 66-73.
28. Takata S, Iwase N, Okuwa H, Okawa J, Ikeda T, Hattori H. Baroreflex function and pressor responsiveness in normotensive young subjects with a family history of hypertension. Jpn Circ J 1985; 49: 990-6.
29. Widgren BR, Herlitz H, Hedner T, et al. Blunted renal sodium excretion during acute saline loading in normotensive men with positive family histories of hypertension. Am J Hypertens 1991; 4: 570-8.
30. Grassi G, Giannattasio C, Saino A, et al. Cardiopulmonary receptor modulation of plasma renin activity in normotensive and hypertensive subjects. Hypertension 1988; 11: 92-9.