Effect of interleukin-2 and interleukin-4 on lymphocytes from peribronchial lymphatic tissue

Experimental Lung Research

Volumn 22, Issue 2, 1996, Pages 245-253

  Or, Reuven ^a   Lossos, Izidore S ^b   Hirschfeld, Esther ^b   Breuer, Raphael ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

hamster; immune system activation; lymphocytes; peribronchial lymphatic tissue; T cells

Indexed keywords

CONCANAVALIN A; MITOGENIC AGENT; RECOMBINANT INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 4;

ANIMAL TISSUE; ARTICLE; BRONCHUS; CELL PROLIFERATION; DNA SYNTHESIS; LYMPHOID TISSUE; MALE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SYRIAN HAMSTER; T LYMPHOCYTE ACTIVATION;

EID: 0029921877     PISSN: 01902148     EISSN: None     Source Type: Journal    
DOI: 10.3109/01902149609050850     Document Type: Article

References (18)

1. Berman JS, Beer DJ, Theodore AC, Kornfeld H, Bernard J, Center DM. Lymphocyte recruitment of the lung. Am Rev Respir Dis. 1990;142:238-257.
2. Hunninghake GW, Gadek JE, Kawanami O, Ferraris V, Crystal RG. Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage. Am J Pathol. 1979;97:149-206.
3. Young KR, Reynolds HY. Bronchoalveolar washings: proteins and cells from normal lungs. In: Bienstock J, ed. Immunology of the Lung and Upper Respiratory Tract. New York: McGraw-Hill; 1984:157-173.
4. Mosmann TR, Coffman RL. Two types of mouse helper T-cell clone: implications for immune regulation. Immunol Today. 1987;8:223-227.
5. Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol. 1989;7:145-173.
6. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cells, IV: Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med. 1989;170:2081-2095.
7. Hu-Li J, Shevach EM, Mizuguchi J, Ohara J, Mosmann T, Paul EW. B cell stimulatory factor I (interleukin 4) is a potent costimulant for normal resting T lymphocytes. J Exp Med. 1987;165: 157-172.
8. Or R, Renz H, Terada N, Gelfand EW. IL-4 and IL-2 promote human T cell proliferation through symmetrical but independent pathways. Clin Immunol Immunopathol. 1992;64:210-217.
9. Brown M, Hu-Li J, Paul WE. IL-4/B cell stimulatory factor 1 stimulates T cell growth by an IL-2-independent mechanism. J Immunol. 1988;141:504-511.
10. Ben Sasson SZ, Le Gros G, Conrad DH, Finkelman FD, Paul WE. IL-4 production by T cells from naive donors: IL-2 is required for IL-4 production. J Immunol. 1990;145:1127-1136.
11. Spits H, Yssel H, Takebe Y, et al. Recombinant interleukin 4 promotes the growth of human T cells. J Immunol. 1987;139:1142-1147.
12. Fiorentino DF, Zlotnik A, Vieira P, et al. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol. 1991;146:3444-3451.
13. Firestein GS, Roeder WD, Laxer JA, et al. A new murine CD4 T cell subset with an unrestricted cytokine profile. J Immunol. 1989;143:518-525.
14. Mills GB, Lee JWW, Gheung RK, Gelfand EW. Characterization of the requirements for human T cell mitogenesis by using suboptimal concentrations of phytohemagglutinin. J Immunol. 1985; 135:3087-3093.
15. Or R, Kovar J, Domenico J, Gelfand EW. Essential fatty acids and iron are involved at distinct stages of the proliferative cycle, but not in the activation of human T cells. Clin Immunol Immunopathol. 1992;62:314-320.
16. Mills GB, Cheung RK, Grinstein S, Gelfand EW. Increase in cytosolic free calcium concentration in an intracellular messenger for the production of interleukin 2, but not for the expression of the interleukin 2 receptor. J Immunol. 1985;134:1640-1643.
17. Kumagai N, Benedict SH, Mills GB, Gelfand EW. Comparison of phorbol ester/calcium ionophore and phytohemagglutinin induced signalling in human T lymphocytes: demonstration of interleukin 2 independent transferrin receptor gene expression. J Immunol. 1988;140:37-43.
18. Kumagai N, Benedict SH, Mills GB, Gelfand EW. Requirements for the simultaneous presence of phorbol esters and calcium ionophores in the expression of human T lymphocyte proliferation-related genes. J Immunol. 1987;139:1393-1399.