Recombinant beta-interferon in the treatment of patients with metastatic renal cell carcinoma

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 19, Issue 2, 1996, Pages 187-189

  Mani, Sridhar ^a,c   Todd, Mary ^a,b   Poo, Wen Jen ^a  

^a YALE CANCER CENTER   (United States)

^b The Cancer Institute New Jersey   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Beta interferon; Renal cell carcinoma

Indexed keywords

RECOMBINANT BETA INTERFERON;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; CARDIOTOXICITY; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DRUG EFFICACY; FATIGUE; FEVER; HEADACHE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY CARCINOMA; KIDNEY METASTASIS; MYALGIA; NAUSEA; PHASE 2 CLINICAL TRIAL; PROTEINURIA; VISUAL DISORDER; VOMITING;

AGED; ANTINEOPLASTIC AGENTS; CARCINOMA, RENAL CELL; COHORT STUDIES; DISEASE PROGRESSION; FATIGUE; HEADACHE; HEART DISEASES; HUMANS; INJECTIONS, INTRAVENOUS; INTERFERON-BETA; KIDNEY NEOPLASMS; MENTAL PROCESSES; MUSCULAR DISEASES; NAUSEA; PROTEINURIA; RECOMBINANT PROTEINS; REMISSION INDUCTION; SURVIVAL RATE; VOMITING;

EID: 0029921871     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-199604000-00020     Document Type: Article

References (19)

1. Harris DT. Hormonal therapy and chemotherapy of renal cell carcinoma. Semin Oncol 1984;10:422-30.
2. Von Roemeling R, Rabatin JT, Fraley EE, et al. Progressive metastatic renal cell carcinoma controlled by continuous 5-fluoro-2-deoxyuridine infusion. J Urol 1988;2:259-62.
3. Muss HB. Renal cell carcinoma. In: DeVita VT, Hellman S, Rosenberg SA, eds. Biologic therapy of cancer. Philadelphia: JB Lippincott, 1991:298-310.
4. Buzaid AC, Todd MB. Therapeutic options in renal cell carcinoma. Semin Oncol 1989;16:12-9.
5. Porzsolt F, Messerer D, Hautmann R, et al. Treatment of advanced renal cell cancer with recombinant interferon alpha as a single agent and in combination with medroxyprogesterone acetate. J Cancer Res Clin Oncol 1988;114:95-100.
6. Trump DL, Elson PJ, Borden EC, et al. Human lymphoblastoid interferon in advanced renal cell cancer: an Eastern Cooperative Oncology Group study. Cancer Treat Rep 1987;71:165-9.
7. Rinehart J, Malspeis L, Young D, et al. Phase I/II trial of human recombinant beta-interferon serine in patients with renal cell carcinoma. Cancer Res 1986;46:5364-7.
8. Geboers ADH, DeMulder PHM, Debruyne FMJ, et al. Alpha and gamma interferon in the treatment of advanced renal cell carcinoma. Semin Surg Oncol 1988;4:191-4.
9. Quesada JR, Evans L, Saks SR, et al. Recombinant interferon alpha and gamma in combination as treatment for metastatic renal cell carcinoma. J Biol Response Mod 1988;7:234-9.
10. Nelson KA, Wallenberg JC, Todd MB. High-dose intravenous therapy with beta-interferon in patients with renal cell cancer. Proc ASCO 1989;30:260.
11. Kohno M, Ida N, Ngos K, et al. Effects of human fibroblast interferon on human tumors transplanted into nude mice. Gan To Kagsku Pyoho 1982;73:945.
12. Shirahama T, Kayajima T, Ohi Y. The antitumor effects of interferon-beta against human renal cell carcinoma in athymic nude mice. In Vivo 1989;3:345-9.
13. Rinehart J, Malspeis L, Young D, Neidhart J. Phase I-II trial of human recombinant beta-interferon serine in patients with renal cell carcinoma. Cancer Res 1986;46:5364-7.
14. Chang AYC, Pandya KJ, Asbury RF, et al. Phase T study of recombinant beta-interferon serine in cancer patients by subcutaneous injection. Proc ASCO 1985;4:226.
15. Ratanatharathorn V, Karanes C, Al-Sarraf M, et al. Phase I trial of serine substituted recombinant DNA beta interferon. Proc ASCO 1985;26:274.
16. Sarna G, Pertcheck M, Figlin R, et al. Phase I study of recombinant beta serine 17 interferon in the treatment of cancer (NCI B83-0015). Report on file, Triton Biosciences, Alameda, CA.
17. Langton BC, Teitelbaum A. Antibody measurements in patients treated with betaseron - interim report (April 10, 1986). Report on file, Triton Biosciences, Almeda, CA.
18. Krigel R, Padavic-Shaller KA, Rudolph AR, et al. A phase I study of recombinant IL-2 plus recombinant beta-interferon. Cancer Res 1988;48:3875-81.
19. Krigel R, Padavic K, Rudolph A, Bradley E, Konrad M, Comis R. Renal cell carcinoma: treatment with recombinant interleukin-2 plus beta-interferon. Proc ASCO 1989;8:186.