NMDA-mediated activation of the NO/cGMP pathway: Characteristics and regulation in cultured neocortical neurones

Journal of Neuroscience Research

Volumn 43, Issue 5, 1996, Pages 623-631

  Carroll, F Y ^a   Beart, P M ^a   Cheung, N S ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

arachidonic acid; calmodulin; flavoproteins; guanylate cyclase; nitric oxide synthase; protein kinase

Indexed keywords

ARACHIDONIC ACID; CALMODULIN; CYCLIC GMP; FLAVOPROTEIN; GLUTAMATE RECEPTOR; GUANYLATE CYCLASE; N METHYL DEXTRO ASPARTIC ACID; NITROUS OXIDE; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN NERVE CELL; ENZYME ACTIVATION; ENZYME INHIBITION; LIGAND BINDING; MOUSE; NEOCORTEX; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; SECOND MESSENGER;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC GMP; MICE; N-METHYLASPARTATE; NEURONS; NITRIC OXIDE;

EID: 0029921603     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19960301)43:5<623::AID-JNR12>3.0.CO;2-1     Document Type: Article

References (58)

1. Agulló L, Garcia A (1992): Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture. Biochem Biophys Res Commun 182: 1362-1368.
2. 2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity. Brain Res 663:237-243.
3. Bean PM, Schousboe A, Frandsen A (1995): Blockade by polyamine NMDA antagonists related to ifenprodil of NMDA-induced synthesis of cyclic GMP, increases in calcium and cytotoxicity in cultured neurones. Br J Pharmacol 114:1359-1364.
4. Ben-Ari Y, Aniksztejn L, Bregestovski P (1992): Protein kinase C modulation of NMDA currents: An important link for LTP induction. Trends Neurosci 15:333-339.
5. Brandt MA, Conrad KP (1991): In vivo and in vitro studies of a putative inhibitor of cyclic guanosine 3′,5′-monophosphate production. Proc Soc Exp Biol Med 196:30-35.
6. Bredt DS, Snyder DH (1994): Nitric oxide: A physiologic messenger molecule. Annu Rev Biochem 63:175-195.
7. Carter C, Benavides J, Dana C, Schoemaker H, Perault G, Sanger D, Scatton B (1991): Non-competitive NMDA receptor antagonists acting on the polyamine site. In Meldrum BS (ed): "Excitatory Amino Acid Antagonists." Oxford: Blackwell, pp 130-163.
8. Choi DW, Koh J, Peters S (1988): Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists. J Neurosci 8:185-196.
9. Courtney MJ, Nicholls DG (1992): Interactions between phospholipase C-coupled and N-methyl-D-aspartate receptors in cultured cerebellar granule cells: Protein kinase C-mediated inhibition of N-methyl-D-aspartate responses. J Neurochem 59:983-992.
10. Dawson VL, Dawson TM, London ED, Bredt DS, Snyder SH (1991): Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc Natl Acad Sci USA 88:6368-6371.
11. Dawson VL, Dawson TM, Bartley DA, Uhl GR, Snyder SH (1993): Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J Neurosci 13:2651-2661.
12. Demerlé-Pallardy C, Lonchampt MO, Chabrier PE, Braquet P (1991): Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury produced by L-glutamate or hypoxia. Biochem Biophys Res Commun 181:456-464.
13. Drian MJ, Kamenka JM, Pirat JL, Privat A (1991): Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex. J Neurosci Res 29:133-138.
14. Gnitroarginine inhibits NMDA-induced cyclic GMP formation in rat cerebellum. Eur J Pharmacol 184:311-313.
15. East SJ, Garthwaite J (1991): NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the L-arginine-nitric oxide pathway. Neurosci Lett 123:17-19.
16. Frandsen A, Schousboe A (1992): Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons. Proc Natl Acad Sci USA 89:2590-2594.
17. Frandsen A, Schousboe A (1993): Excitatory amino acid-mediated cytotoxicity and calcium homeostasis in cultured neurons. J Neurochem 60:1202-1211.
18. Frandsen A, Andersen CF, Schousboe A (1992): Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons. Neurochem Res 17:35-43.
19. Gill R, Woodruff GN (1990): The neuroprotective actions of kynurenic acid and MK-801 in gerbils are synergistic and not related to hyperthermia. Eur J Pharmacol 176:143-149.
20. Gill R, Foster AC, Woodruff GN (1987): Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil. J Neurosci 7:3343-3349.
21. Hertz E, Yu ACH, Hertz L, Juurlink BHJ, Schousboe A (1989): Preparation of primary cultures of mouse cortical neurons. In Shahar A, de Vellis J, Vernadakis A, Haber B (eds): "A Dissection and Tissue Culture Manual of the Nervous System." New York: Alan R. Liss, pp 183-186
22. Hewett SJ, Corbett JA, McDaniel ML, Choi DW (1993): Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity. Brain Res 624:337-341.
23. Hollmann M, Heinemann S (1994): Cloned glutamate receptors. Annu Rev Neurosci 17:31-108.
24. ω-Nitro-L-arginine: A potent inhibitor of endothelium-derived relaxing factor formation. Eur J Pharmacol 176:219-223.
25. Izumi Y, Benz AM, Clifford DB, Zorumski CF (1992): Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices. Neurosci Lett 135:227-230.
26. 3H] aspartate. J Neurochem 64:2057-2063.
27. Kemp JA, Foster AC, Leeson PD, Priestley T, Tridgett R, Iversen LL (1988): 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc Natl Acad Sci USA 85:6547-6550.
28. Knowles RG, Palacios M, Palmer RMJ, Moncada S (1989): Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for the stimulation of the soluble guanylate cyclase. Proc Natl Acad Sci USA 86:5159-5162.
29. Laychock SG (1989): Coordinate interactions of the cyclic nucleotide and phospholipid metabolizing pathways in calcium-dependent cellular processes. Curr Top Cell Regul 30:203-242.
30. Lipton SA, Choi Y, Pan Z, Lei SZ, Chen HV, Sucher NJ, Loscaizo J, Singel DJ, Stamler JS (1993): A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso compounds. Nature 364:626-632.
31. Marin P, Lafon-Cazal M, Bockaert J (1992): A nitric oxide synthase activity selectively stimulated by NMDA receptors depends on protein kinase C activation in mouse striatal neurons. Eur J Neurosci 4:425-432.
32. Marley PD, Thompson KA (1992): Regulation of cyclic AMP metabolism in bovine adrenal medullary cells. Biochem Pharmacol 44:2105-2110.
33. Mattson MP, Scheff SW (1994): Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy. J Neurotrauma 11:3-33.
34. McBain CJ, Mayer ML (1994): N-methyl-D-aspartate acid receptor structure and function. Physiol Rev 74:723-760.
35. McDonald JW, Johnston MV (1990): Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Res Rev 15:41-70.
36. Meldrum B, Garthwaite J (1990): Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol Sci 11:379-387.
37. 2+ -ATPase inhibitor, relaxes rat aorta via nitric oxide formation. Life Sci 54:153-158.
38. Morris R, Southam E, Gittens SR, de Vente J, Garthwaite J (1994): The NO-cGMP pathway in neonatal rat dorsal horn. Eur J Neurosci 6:876-879.
39. Novelli A, Nicoletti F, Wroblewski JT, Alho H, Costa E, Guidotti A (1987): Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells. J Neurosci 7:40-47.
40. Pauwels PJ, Leysen JE (1992): Blockade of nitric oxide formation does not prevent glutamate-induced neurotoxicity in neuronal cultures from rat hippocampus. Neurosci Lett 143:27-30.
41. Rao TS, Gray NM, Dappen MS, Cler JA, Mick SJ, Emmett MR, Iyengar S, Monahan JB, Cordi AA, Wood PL (1993): Indole-2-carboxylates, novel antagonists of the N-methyl-D-aspartate (NMDA)-associated glycine recognition sites: In vivo characterization. Neuropharmacol 32:139-147.
42. Regan RF, Choi DW (1994): The effect of NMDA, AMPA/kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture. Brain Res 633:236-242.
43. Salvemini D, Radzizewski W, Mollace V, Moore A, Willoughby D, Vane J (1991): Diphenyleniodonium, an inhibitor of free radical formation inhibits platelet aggregation. Eur J Pharm 199: 15-18.
44. Simon RP, Swan JH, Griffiths T, Meldrum BS (1984): Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain. Science 226:850-852.
45. Southam E, Garthwaite J (1991): Comparative effects of some nitric oxide donors on cyclic GMP levels in rat cerebellar slices. Neurosci Lett 130:107-111.
46. Southam E, East SJ, Garthwaite J (1991): Excitatory amino acid receptors coupled to the nitric oxide/cyclic GMP pathway in rat cerebellum during development. J Neurochem 56:2072-2081.
47. Stuehr DJ, Fasehun OA, Kwon NS, Gross SS, Gonzalez JA, Levi R, Nathan CF (1991): Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs. FASEB J 5:98-103.
48. Tanaka C, Nishizuka Y (1994): The protein kinase C family for neuronal signalling. Annu Rev Neurosci 17:551-567.
49. 2+/calmodulin-dependent protein kinase II. J Biol Chem 265:4315-4320.
50. Wang YX, Poon CI, Poon KS, Pang CCY (1993): Inhibitory actions of diphenyleneiodonium on endothelium dependent vasodilations in vitro and in vivo. Br J Pharmacol 110:1232-1238.
51. 3H]arginine in cultured neurons: Characteristics and inhibition by nitric oxide synthase inhibitors. J Neurochem 61:364-367.
52. Wilkinson SE, Hallam TJ (1994): Protein kinase C: Is its pivotal role in cellular activation overstated? Trends Pharmacol Sci 15:53-57.
53. Williams JH, Errington ML, Lynch MA, Bliss TVP (1989): Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus. Nature 341:739-742.
54. Wong EHF, Kemp JA (1991): Sites for antagonism of the N-methyl-D-aspartate receptor channel complex. Annu Rev Pharmacol Toxicol 31:401-425.
55. Wong EHF, Kemp JA, Priestley T, Knight AR, Woodruff GN, Iversen LL (1986): The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci USA 83: 7104-7108.
56. Wood PL, Rao TS (1991): A review of in vivo modulation of cerebellar cGMP levels by excitatory amino acid receptors: Role of NMDA, quisqualate and kainate subtypes. Prog Neuropsychopharmacol Biol Psychiatry 15:229-235.
57. Zhong J, Russell SL, Pritchett DB, Molinoff PB, Williams K (1994): Expression of mRNAs encoding subunits of the N-methyl-D-aspartate receptor in cultured cortical neurons. Mol Pharmacol 45:846-853.
58. Zimmerman DM, Schoepp DD, Leander JD, Ornstein P (1992): The discovery and characterization of the competitive NMDA antagonists LY 274614, LY233536 and LY233053. Mol Neuropharmacol 2:77-82.