Comparison of myeloma cell contamination of bone marrow and peripheral blood stem cell harvests

British Journal of Haematology

Volumn 92, Issue 3, 1996, Pages 614-619

  Henry, Julianne M ^a   Sykes, Pamela J ^a   Brisco, Michael J ^a   To, Luen Bik ^b   Juttner, Christopher A ^b   Morley, Alexander A ^a  

^a FLINDERS MEDICAL CENTRE   (Australia)

^b INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

Autologous transplantation; Multiple myeloma; PCR quantification; Peripheral blood stem cells; Residual disease

Indexed keywords

CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DOXORUBICIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN HEAVY CHAIN; METHYLPREDNISOLONE; PREDNISOLONE; VINCRISTINE;

ADULT; ARTICLE; BONE MARROW CELL; CLINICAL ARTICLE; CONTROLLED STUDY; GENE REARRANGEMENT; HUMAN; HUMAN CELL; MINIMAL RESIDUAL DISEASE; MULTIPLE MYELOMA; MYELOMA CELL; PERIPHERAL BLOOD STEM CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; STEM CELL TRANSPLANTATION;

EID: 0029921561     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.00381.x     Document Type: Article

References (23)

1. Billadeau, D., Quam, L., Thomas, W., Kay, N., Greipp, P., Kyle, R., Oken, M.M. & Van Ness, B. (1992) Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients. Blood, 80, 1818-1824.
2. Brenner, M.K., Rill, D.R., Krance, R.A., Mirro, J., Anderson, W.F. & Ihle, J.N. (1993) Gene-marking to trace origin of relapse after autologous bone-marrow transplantation. Lancet, 341, 85-86.
3. Brisco, M.J., Condon, J., Hughes, E., Neoh, S.H., Sykes, P.J., Seshadri, R., Toogood, I., Waters, K., Tauro, G., Ekert, H. & Morley, A.A. (1994) Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of induction. Lancet, 343, 196-200.
4. Brisco, M.J., Condon, J., Sykes, P.J., Neoh, S.H. & Morley, A.A. (1991) Detection and quantitation of neoplastic cells in acute lymphoblastic leukaemia, by use of the polymerase chain reaction. British Journal of Haematology, 79, 211-217.
5. Chou, Q., Russell, M., Birch, D.E., Raymond, J. & Bloch, W. (1992) Prevention of pre-PCR mis-priming and primer dimerization improves low-copy-number amplilications. Nucleic Acids Research, 20, 1717-1723.
6. Corradini, P., Voena, C., Omedé, P., Astolfi, M., Boccadoro, M., Dalla-Favera, R. & Pileri, A. (1993) Detection of circulating tumour cells in multiple myeloma by a PCR-based method. Leukemia, 7, 1879-1882.
7. Craig, J.I.O., Langlands, K., Parker, A.C. & Anthony, R.S. (1994) Molecular detection of tumor contamination in peripheral blood stem cell harvests. Experimental Hematology, 22, 898-902.
8. Deane, M. & Norton, J.D. (1990) Immunoglobulin gene 'fingerprinting': an approach to analysis of B lymphoid clonality in lymphoproliferative disorders. British Journal of Haematology, 77, 274-281.
9. Dreyfus, F., Melle, J., Quarre, M.C. & Pillier, C. (1993) Contamination of peripheral blood by monoclonal B cells following treatment of multiple myeloma by high-dose chemotherapy. British Journal of Haematology, 85, 411-412.
10. Gianni, A.M., Siena, S. & Bregni M. (1989) Granulocyte-macrophage colony stimulating factor to harvest circulating haemopoietic stem cells for autotransplantation. Lancet, ii, 580-585.
11. Gribben, J.G., Saporito, L., Barber, M., Blake, K., Edwards, R.M., Griffen, J.D., Freedman, A.S. & Nadler, L.M. (1992) Bone marrows of non-Hodgkin's lymphoma patients with a bcl-2 translocation can be purged of polymerase chain reaction-detectable lymphoma cells using monoclonal antibodies and immunomagnetic bead depletion. Blood, 80, 1083-1089.
12. Henon, P.R. (1993) Peripheral blood stem cell transplantations: past, present and future. Stem Cells , 11, 154-172.
13. Jeffreys, A.J., Wilson, V., Neumann, R. & Keyte, J. (1988) Amplification of human mini-satellites by the polymerase chain reaction: toward DNA fingerprinting single cells. Nucleic Acids Research, 16, 10953-10971.
14. Levy, Y., Schmitt, C., Tsapis, A., Brouet, J.C. & Fermand, J.C. (1991) Phenotype and immunoglobulin gene configuration of B blood cells from patients with multiple myeloma. Clinical and Experimental Immunology, 84, 435-439.
15. Mariette, X., Fermand, J.P. & Brouet, J.C. (1994) Myeloma cell contamination of peripheral blood stem cell grafts in patients with multiple myeloma treated by high-dose therapy. Bone Marrow Transplantation, 14, 47-50
16. Ralph, Q.M., Brisco, M.J., Joshua, D.E., Brown, R., Gibson, J. & Morley, A.A. (1993) Advancement of multiple myeloma from diagnosis through plateau phase to progression does not involve a new B-cell clone: evidence from the immunoglobulin heavy chain gene. Blood, 82, 202-206.
17. Sharp, J.G., Joshi, S.S., Armitage, J.O., Bierman, P., Coccia, P.F., Harrington, D.S., Kessinger, A., Crouse, D.A., Mann, S.L. & Weisenburger, D.D. (1992) Significance of detection of occult non-Hodgkin's lymphoma in histologically uninvolved bone marrow by a culture technique. Blood, 79, 1074-1080.
18. Sykes, P.J., Neoh, S.H., Brisco, M.J., Hughes, E., Condon, J. & Morley, A.A. (1992) Quantitation of targets for PCR by use of limiting dilution. Biotechniques, 13, 444-449.
19. Taswell, C. (1981) Limiting dilution assays for the determination of immunocompetent cell frequencies. Journal of Immunology, 126, 1614-1619.
20. To, L.B., Roberts, M.M., Haylock, D.N., Dyson, P.G., Branford, A.L., Thorp, D., Ho, J.K.Q., Dart, G.W., Horvath, N., Davy, M.L.J., Olweny, C.L.M., Abdi, E. & Juttner, C.A. (1992) Comparison of haematological recovery times and supportive care requirements for autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants. Bone Marrow Transplantion, 9, 277-284.
21. Tonegawa, S. (1983) Somatic generation of antibody diversity. Nature, 302, 575-581.
22. Van Riet, I., Heirman, C., Lacor, P., De Waele, M., Thielemans, K. & Van Kamp, B. (1989) Detection of monoclonal B lymphocytes in bone marrow and peripheral blood of multiple myeloma patients by immunoglobulin gene rearrangement studies. British Journal of Haematology, 73, 289-295.
23. Witzig, T.E., Dhodapkar, M.V., Kyle, R.A. & Greipp, P.R. (1993) Quantitation of circulating peripheral blood plasma cells and their relationship to disease activity in patients with multiple myeloma. Cancer, 72, 108-113.