Immunologic responses to isocyanates in sensitized asthmatic subjects

Chest

Volumn 109, Issue 3 SUPPL., 1996, Pages 6S-8S

  Redlich, Carrie A ^a   Homer, Robert J ^a   Smith, Brian R ^a   Wirth, Joel A ^a   Cullen, Mark R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOCYANATE;

ADULT; ANTIGEN SPECIFICITY; BASEMENT MEMBRANE; BRONCHUS HYPERREACTIVITY; CASE REPORT; CONFERENCE PAPER; DRUG SENSITIVITY; HISTOLOGY; HUMAN; IMMUNE RESPONSE; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; OCCUPATIONAL ASTHMA; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; T LYMPHOCYTE;

AIR POLLUTANTS, OCCUPATIONAL; ASTHMA; CD4-CD8 RATIO; HUMANS; ISOCYANATES; OCCUPATIONAL DISEASES; T-LYMPHOCYTES;

EID: 0029921507     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.109.3_Supplement.6S     Document Type: Article

References (8)

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2. Vandenplas O, Malo JL, Saetta M, et al. Occupational asthma and extrinsic allergic alveolitis due to isocyanates: current status and perspectives. Br J Ind Med 1993; 50:213-18
3. Mapp CE, Saetta M, Maestrelli P, et al. Mechanisms and pathology of occupational asthma. Eur Respir J 1994; 7:544-54
4. Saetta M, Di Stefano A, Maestrelli P, et al. Airway mucosal inflammation in occupational asthma induced by toluene diisocyanate. Am Rev Respir Dis 1992; 145:160-68
5. Saetta M, Di Stefano A, Maestrelli P, et al. Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis. Am Rev Respir Dis 1993; 147:301-06
6. Bentley AM, Maestrelli P, Saetta M, et al. Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma. J Allergy Clin Immunol 1992; 89:821-29
7. Finotto S, Fabbri LM, Rado V, et al. Increase in numbers of CD8 positive lymphocytes and eosinophils in peripheral blood of subjects with late asthmatic reactions induced by toluene diisocyanate. Br J Indust Med 1991;48:116-21
8. Maestrelli P, Del Prete GF, De Carli M, et al. CD8 T-cell clones producing interleuldn-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate. Scand J Work Environ Health 1994; 20:376-81