-
1
-
-
0027096062
-
Oxidants are a major contributor to aging
-
AMES, B.N. and SHIGENAGA, M.K. Oxidants are a major contributor to aging. Ann. NY Acad. Sci. 663, 85-96, 1992.
-
(1992)
Ann. NY Acad. Sci.
, vol.663
, pp. 85-96
-
-
Ames, B.N.1
Shigenaga, M.K.2
-
2
-
-
0017166058
-
Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos
-
BENN, P.A. Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos. Am. J. Hum. Genet. 28, 465-473, 1976.
-
(1976)
Am. J. Hum. Genet.
, vol.28
, pp. 465-473
-
-
Benn, P.A.1
-
3
-
-
0021905437
-
DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall
-
BOHR, V.A., SMITH, C.A., OKUMOTO, D.S., and HANAWALT, P.C. DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell 40, 359-369, 1985.
-
(1985)
Cell
, vol.40
, pp. 359-369
-
-
Bohr, V.A.1
Smith, C.A.2
Okumoto, D.S.3
Hanawalt, P.C.4
-
4
-
-
0028261160
-
Escape from senescence in human diploid fibroblasts induced directly by mutant p53
-
BOND, J.A., WYLLIE, F.S., and WYNFORD-THOMAS, D. Escape from senescence in human diploid fibroblasts induced directly by mutant p53. Oncogene 9, 1885-1889, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 1885-1889
-
-
Bond, J.A.1
Wyllie, F.S.2
Wynford-Thomas, D.3
-
5
-
-
0028345161
-
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
-
CHEN, Q. and AMES, B.N. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc. Natl Acad. Sci. USA 91, 4130-4134, 1994.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 4130-4134
-
-
Chen, Q.1
Ames, B.N.2
-
6
-
-
0019499028
-
Evidence for an increased level of DNA damage in high doubling level human diploid cells culture
-
DELL'ORCO, R.T., and WHITTLE, W.L. Evidence for an increased level of DNA damage in high doubling level human diploid cells culture. Mech. Ageing Dev. 15, 141-152, 1981.
-
(1981)
Mech. Ageing Dev.
, vol.15
, pp. 141-152
-
-
Dell'orco, R.T.1
Whittle, W.L.2
-
7
-
-
0028342951
-
Repair of oxidative damage to DNA: Enzymology and biology
-
DEMPLE, B., and HARRISON, L. Repair of oxidative damage to DNA: Enzymology and biology. Annu. Rev. Biochem. 63, 915-948, 1994.
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 915-948
-
-
Demple, B.1
Harrison, L.2
-
8
-
-
0026737695
-
Oxidative damage to DNA in mammalian chromatin
-
DIZDAROGLU, M. Oxidative damage to DNA in mammalian chromatin. Mutat. Res. 275, 331-342, 1992.
-
(1992)
Mutat. Res.
, vol.275
, pp. 331-342
-
-
Dizdaroglu, M.1
-
9
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
EL-DEIRY, W.S., TOKINO, T., VELCULESCU, V.E., LEVY, D.B., PARSONS, R, TRENT, J.M., LIN, D., MERCER, W.E., KINZLER, K.W., and VOGELSTEIN, B. WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
10
-
-
0028294605
-
1 arrest and apoptosis
-
1 arrest and apoptosis. Cancer Res. 54, 1169-1174, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.10
Wiman, K.G.11
Mercer, W.E.12
Kastan, M.B.13
Kohn, K.W.14
Elledge, S.J.15
Kinzler, K.W.16
Vogelstein, B.17
-
11
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
FISHEL, R., LESCOE, M.K., RAO, M.R.S., COPELAND, N.G., JENKINS, N.A., GARBER, J., KANE, M., and KOLODNER, R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75, 1027-1038, 1993.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.S.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
12
-
-
0019481131
-
On the activity and fidelity of chromatin-associated hepatic DNA polymerase-β in aging murine species of different life spans
-
FRY, M., LOEB, L.A., and MARTIN, G.M. On the activity and fidelity of chromatin-associated hepatic DNA polymerase-β in aging murine species of different life spans. J. Cell. Physiol. 106, 435-444, 1981.
-
(1981)
J. Cell. Physiol.
, vol.106
, pp. 435-444
-
-
Fry, M.1
Loeb, L.A.2
Martin, G.M.3
-
13
-
-
0016840454
-
A rapid rise in cell variants during the senescence of populations of human fibroblasts
-
FULDER, S.J., and HOLLIDAY, R. A rapid rise in cell variants during the senescence of populations of human fibroblasts. Cell 6, 67-73, 1975.
-
(1975)
Cell
, vol.6
, pp. 67-73
-
-
Fulder, S.J.1
Holliday, R.2
-
14
-
-
0021346772
-
Effect of 2-mercaptoethylamine on proliferation and lifespan of WI-38 cells
-
GOLCZEWSKI, J.A. Effect of 2-mercaptoethylamine on proliferation and lifespan of WI-38 cells. Exp. Gerontol. 19, 7-11, 1984.
-
(1984)
Exp. Gerontol.
, vol.19
, pp. 7-11
-
-
Golczewski, J.A.1
-
15
-
-
0025145238
-
Replicative senescence: The human fibroblast comes of age
-
GOLDSTEIN, S. Replicative senescence: The human fibroblast comes of age. Science 249, 1129-1133, 1990.
-
(1990)
Science
, vol.249
, pp. 1129-1133
-
-
Goldstein, S.1
-
16
-
-
0027435938
-
The rapid detection of unknown mutations in nucleic acids
-
GROMPE, M. The rapid detection of unknown mutations in nucleic acids. Nat. Genet. 5, 111-117, 1993.
-
(1993)
Nat. Genet.
, vol.5
, pp. 111-117
-
-
Grompe, M.1
-
17
-
-
0027731971
-
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
-
GU, Y., TURCK, C.W., and MORGAN, D.O. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366, 707-710, 1993.
-
(1993)
Nature
, vol.366
, pp. 707-710
-
-
Gu, Y.1
Turck, C.W.2
Morgan, D.O.3
-
18
-
-
0019274638
-
Senescence of cultured human diploid fibroblasts. Are mutations responsible?
-
GUPTA, R.S. Senescence of cultured human diploid fibroblasts. Are mutations responsible? J. Cell. Physiol. 103, 209-216, 1980.
-
(1980)
J. Cell. Physiol.
, vol.103
, pp. 209-216
-
-
Gupta, R.S.1
-
19
-
-
0028941483
-
Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD
-
HALEVY, O., NOVITCH, B.C., SPICER, D.B., SKAPEK, S.X., RHEE, J., HANNON, G.J., BEACH, D., and LASSAR, A.B. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267, 1018-1021, 1995.
-
(1995)
Science
, vol.267
, pp. 1018-1021
-
-
Halevy, O.1
Novitch, B.C.2
Spicer, D.B.3
Skapek, S.X.4
Rhee, J.5
Hannon, G.J.6
Beach, D.7
Lassar, A.B.8
-
20
-
-
0027078198
-
Genomic heterogeneity of DNA repair
-
HANAWALT, P.C., GEE, P., HO, L., HSU, R.K, and KANE, C.J.M. Genomic heterogeneity of DNA repair. Ann. NY Acad. Sci. 663, 17-25, 1992.
-
(1992)
Ann. NY Acad. Sci.
, vol.663
, pp. 17-25
-
-
Hanawalt, P.C.1
Gee, P.2
Ho, L.3
Hsu, R.K.4
Kane, C.J.M.5
-
21
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
HARLEY, C.B., FUTCHER, A.B., and GREIDER, C.W. Telomeres shorten during ageing of human fibroblasts. Nature 345, 458-460, 1990.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
22
-
-
0002491536
-
The free radical theory of aging
-
Warner, H.R., Butler, R.N., Sprott, R.L., and Schneider, E.L. (Editors), Raven Press, New York
-
HARMAN, D. The free radical theory of aging. In: Modern Biological Theories of Aging, Warner, H.R., Butler, R.N., Sprott, R.L., and Schneider, E.L. (Editors), pp. 81-87, Raven Press, New York, 1987.
-
(1987)
Modern Biological Theories of Aging
, pp. 81-87
-
-
Harman, D.1
-
23
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1cyclin-dependent kinases
-
HARPER, J.W., ADAMI, G.R., WEI, N., KEYOMARSI, K., and ELLEDGE, S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1cyclin-dependent kinases. Cell 75, 805-816, 1993.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
24
-
-
0026452949
-
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
-
HARTWELL, L. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71, 543-546, 1992.
-
(1992)
Cell
, vol.71
, pp. 543-546
-
-
Hartwell, L.1
-
25
-
-
0026230108
-
Response to adversity: Molecular control of gene activation following genotoxic stress
-
HOLBROOK, N.J., and FORNACE, A.J., JR. Response to adversity: Molecular control of gene activation following genotoxic stress. New Biol. 3, 825-833, 1991.
-
(1991)
New Biol.
, vol.3
, pp. 825-833
-
-
Holbrook, N.J.1
Fornace A.J., Jr.2
-
26
-
-
0025751674
-
A reexamination of the effects of ionizing radiation on lifespan and transformation of human diploid fibroblasts
-
HOLLIDAY, R. A reexamination of the effects of ionizing radiation on lifespan and transformation of human diploid fibroblasts. Mutat. Res. 256, 295-302, 1991.
-
(1991)
Mutat. Res.
, vol.256
, pp. 295-302
-
-
Holliday, R.1
-
27
-
-
0019135030
-
Spontaneous structural changes in DNA during fibroblast aging and the establishment process in vitro
-
ICARD, C. and BEAUPAIN, R. Spontaneous structural changes in DNA during fibroblast aging and the establishment process in vitro. Mech. Ageing Dev. 14, 81-87, 1980.
-
(1980)
Mech. Ageing Dev.
, vol.14
, pp. 81-87
-
-
Icard, C.1
Beaupain, R.2
-
29
-
-
0022235486
-
Mechanisms of human cell neoplastic transformation: Relationship of specific abnormal clone formation to prolonged lifespan in X-irradiated human diploid fibroblasts
-
KANO, Y. and LITTLE, J.B. Mechanisms of human cell neoplastic transformation: Relationship of specific abnormal clone formation to prolonged lifespan in X-irradiated human diploid fibroblasts. Int. J. Cancer 36, 407-413, 1985.
-
(1985)
Int. J. Cancer
, vol.36
, pp. 407-413
-
-
Kano, Y.1
Little, J.B.2
-
30
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
KASTAN, M.B., ONYEKWERE, O., SIDRANSKY, D., VOGELSTEIN, B., and CRAIG, R.W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51, 6304-6311, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
31
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
KIM, N.W., PIATYSZEK, M.A., PROWSE, K.R., HARLEY, C.B., WEST, M.D., HO, P.L.C., COVIELLO, G.M., WRIGHT, W.E., WEINRICH, S.L., and SHAY, J.W. Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011-2015, 1994.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.C.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
32
-
-
0020473253
-
Changes in DNA polymerases α, β, and γ during the replicative life span of cultured human fibroblasts
-
KRAUSS, S.W., and LINN, S. Changes in DNA polymerases α, β, and γ during the replicative life span of cultured human fibroblasts. Biochemistry 21, 1002-1009, 1982.
-
(1982)
Biochemistry
, vol.21
, pp. 1002-1009
-
-
Krauss, S.W.1
Linn, S.2
-
33
-
-
0028909019
-
DNA damage and repair in telomeres: Relation to aging
-
KRUK, P.A., RAMPINO, N.J., and BOHR, V.A. DNA damage and repair in telomeres: Relation to aging. Proc. Natl. Acad. Sci. USA 92, 258-262, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 258-262
-
-
Kruk, P.A.1
Rampino, N.J.2
Bohr, V.A.3
-
34
-
-
0028074603
-
Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair
-
LI, R., WAGA, S., HANNON, G.J., BEACH, D., and STILLMAN, B. Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature 371, 534-537, 1994.
-
(1994)
Nature
, vol.371
, pp. 534-537
-
-
Li, R.1
Waga, S.2
Hannon, G.J.3
Beach, D.4
Stillman, B.5
-
35
-
-
0017159508
-
Decreased fidelity of DNA polymerase activity isolated from aging human fibroblasts
-
LINN, S., KAIRIS, M., and HOLLIDAY, R. Decreased fidelity of DNA polymerase activity isolated from aging human fibroblasts. Proc. Natl. Acad. Sci. USA 73, 2818-2822, 1976.
-
(1976)
Proc. Natl. Acad. Sci. USA
, vol.73
, pp. 2818-2822
-
-
Linn, S.1
Kairis, M.2
Holliday, R.3
-
36
-
-
0022500040
-
Differential DNA repair in transcriptionally active and inactive proto-oncogenes: C-abl and c-mos
-
MADHANI, H.D., BOHR, V.A., and HANAWALT, P.C. Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos. Cell 45, 417-423, 1986.
-
(1986)
Cell
, vol.45
, pp. 417-423
-
-
Madhani, H.D.1
Bohr, V.A.2
Hanawalt, P.C.3
-
37
-
-
0022460718
-
No change in DNA damage or repair of single- and double-strand breaks as human diploid fibroblasts age in vitro
-
MAYER, P.J., BRADLEY, M.O., and NICHOLS, W.W. No change in DNA damage or repair of single- and double-strand breaks as human diploid fibroblasts age in vitro. Exp. Cell Res. 166, 497-509, 1986.
-
(1986)
Exp. Cell Res.
, vol.166
, pp. 497-509
-
-
Mayer, P.J.1
Bradley, M.O.2
Nichols, W.W.3
-
38
-
-
0025866760
-
Diverse gene sequences are overexpressed in Werner syndrome fibroblasts undergoing premature replicative senescence
-
MURANO, S., THWEATT, R., SHMOOKLER REIS, R.J., JONES, R.A., MOERMAN, E.J., and GOLDSTEIN, S. Diverse gene sequences are overexpressed in Werner syndrome fibroblasts undergoing premature replicative senescence. Mol. Cell Biol. 11, 3905-3914, 1991.
-
(1991)
Mol. Cell Biol.
, vol.11
, pp. 3905-3914
-
-
Murano, S.1
Thweatt, R.2
Shmookler Reis, R.J.3
Jones, R.A.4
Moerman, E.J.5
Goldstein, S.6
-
39
-
-
0025953702
-
Genetic analysis of indefinite division in human cells: Evidence for a cell senescence-related gene(s) on human chromosome 4
-
NING, Y., WEBER, J.L., KILLARY, A.M., LEDBETTER, D.H., SMITH, J.R., and PEREIRA-SMITH, O.M. Genetic analysis of indefinite division in human cells: Evidence for a cell senescence-related gene(s) on human chromosome 4. Proc. Natl. Acad. Sci. USA 88, 5635-5639, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 5635-5639
-
-
Ning, Y.1
Weber, J.L.2
Killary, A.M.3
Ledbetter, D.H.4
Smith, J.R.5
Pereira-Smith, O.M.6
-
40
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
NODA, A., NING, Y., VENABLE, S.F., PEREIRA-SMITH, O.M., and SMITH, J.R. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211, 90-98, 1994.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
41
-
-
0025316007
-
Cytotoxic effects of expression of human superoxide dismutase in bovine adrenocortical cells
-
NORRIS, K.H. and HORNSBY, P.J. Cytotoxic effects of expression of human superoxide dismutase in bovine adrenocortical cells. Mutat. Res. 237, 95-106, 1990.
-
(1990)
Mutat. Res.
, vol.237
, pp. 95-106
-
-
Norris, K.H.1
Hornsby, P.J.2
-
42
-
-
0011888336
-
Dominance of the senescent phenotype in heterokaryons between replicative and postreplicative human fibroblast-like cells
-
NORWOOD, T.H., PENDERGRASS, W.R., SPRAGUE, C.A., and MARTIN, G.M. Dominance of the senescent phenotype in heterokaryons between replicative and postreplicative human fibroblast-like cells. Proc. Natl. Acad. Sci. USA 71, 2231-2235, 1974.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 2231-2235
-
-
Norwood, T.H.1
Pendergrass, W.R.2
Sprague, C.A.3
Martin, G.M.4
-
43
-
-
0000547195
-
Aging at the cellular level: The human fibroblast cell model
-
Schneider, E.L. and Rowe, J.W. (Editors), Academic Press, New York
-
NORWOOD, T.H., SMITH, J.R., and STEIN, G.H. Aging at the cellular level: The human fibroblast cell model. In: Handbook of the Biology of Aging, 3rd ed., Schneider, E.L. and Rowe, J.W. (Editors), pp. 131-154, Academic Press, New York, 1990.
-
(1990)
Handbook of the Biology of Aging, 3rd Ed.
, pp. 131-154
-
-
Norwood, T.H.1
Smith, J.R.2
Stein, G.H.3
-
44
-
-
0027193034
-
Cyclin-dependent regulation of G1 in mammalian fibroblasts
-
OHTSUBO, M., and ROBERTS, J.M. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science 259, 1908-1912, 1993.
-
(1993)
Science
, vol.259
, pp. 1908-1912
-
-
Ohtsubo, M.1
Roberts, J.M.2
-
45
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
ORR, W.C. and SOHAL, R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263, 1128-1130, 1994.
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
46
-
-
0028986639
-
Cip1 in muscle and other terminally differentiating cells
-
Cip1 in muscle and other terminally differentiating cells. Science 267, 1024-1027, 1995.
-
(1995)
Science
, vol.267
, pp. 1024-1027
-
-
Parker, S.B.1
Eichele, G.2
Zhang, P.3
Rawls, A.4
Sands, A.T.5
Bradley, A.6
Olson, E.N.7
Harper, J.W.8
Elledge, S.J.9
-
47
-
-
0020610446
-
Evidence for the recessive nature of cellular immortality
-
PEREIRA-SMITH, O.M. and SMITH, J.R. Evidence for the recessive nature of cellular immortality. Science 221, 964-966, 1983.
-
(1983)
Science
, vol.221
, pp. 964-966
-
-
Pereira-Smith, O.M.1
Smith, J.R.2
-
48
-
-
0028072520
-
Joining the complex: Cyclin-dependent kinase inhibitory proteins and the cell cycle
-
PETER, M. and HERSKOWITZ, I. Joining the complex: Cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell 79, 181-184, 1994.
-
(1994)
Cell
, vol.79
, pp. 181-184
-
-
Peter, M.1
Herskowitz, I.2
-
49
-
-
0028329787
-
Arresting developments in cell-cycle control
-
PINES, J. Arresting developments in cell-cycle control. Trends Biochem. Sci. 19, 143-145, 1994.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 143-145
-
-
Pines, J.1
-
50
-
-
0025748840
-
Oxidants and antioxidants in proliferative senescence
-
POOT, M. Oxidants and antioxidants in proliferative senescence. Mutat. Res. 256, 177-189, 1991.
-
(1991)
Mutat. Res.
, vol.256
, pp. 177-189
-
-
Poot, M.1
-
51
-
-
0019122394
-
Comparative heterokaryon study of cellular senescence and the serum-deprived state
-
RABINOVITCH, P.S. and NORWOOD, T.H. Comparative heterokaryon study of cellular senescence and the serum-deprived state. Exp. Cell Res. 130, 101-109, 1980.
-
(1980)
Exp. Cell Res.
, vol.130
, pp. 101-109
-
-
Rabinovitch, P.S.1
Norwood, T.H.2
-
52
-
-
0024343128
-
DNA damage and repair during cellular aging
-
RATTAN, S.I.S. DNA damage and repair during cellular aging. Int. Rev. Cytol. 116, 47-88, 1989.
-
(1989)
Int. Rev. Cytol.
, vol.116
, pp. 47-88
-
-
Rattan, S.I.S.1
-
53
-
-
0000299214
-
Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo
-
RÖHME, D. Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo. Proc. Natl. Acad. Sci. USA 78, 5009-5013, 1981.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 5009-5013
-
-
Röhme, D.1
-
54
-
-
0026086703
-
Mechanisms responsible for the limited lifespan and immortal phenotypes in cultured mammalian cells
-
ROSENBERGER, R.F., GOUNARIS, E., and KOLETTAS, E. Mechanisms responsible for the limited lifespan and immortal phenotypes in cultured mammalian cells. J. Theor. Biol. 148, 383-392, 1991.
-
(1991)
J. Theor. Biol.
, vol.148
, pp. 383-392
-
-
Rosenberger, R.F.1
Gounaris, E.2
Kolettas, E.3
-
55
-
-
84883833036
-
Aneuploidy in the degenerative phase of serial cultivation of human cell strains
-
SAKSELA, E. and MOORHEAD, P.S. Aneuploidy in the degenerative phase of serial cultivation of human cell strains. Proc. Natl. Acad. Sci. USA 50, 390-395, 1963.
-
(1963)
Proc. Natl. Acad. Sci. USA
, vol.50
, pp. 390-395
-
-
Saksela, E.1
Moorhead, P.S.2
-
56
-
-
0027421043
-
Loss of a yeast telomere: Arrest, recovery, and chromosome loss
-
SANDELL, L.L. and ZAKIAN, V.A. Loss of a yeast telomere: Arrest, recovery, and chromosome loss. Cell 75, 729-739, 1993.
-
(1993)
Cell
, vol.75
, pp. 729-739
-
-
Sandell, L.L.1
Zakian, V.A.2
-
57
-
-
0026054961
-
A role for both RB and p53 in the regulation of human cellular senescence
-
SHAY, J.W., PEREIRA-SMITH, O.M., and WRIGHT, W.E. A role for both RB and p53 in the regulation of human cellular senescence. Exp. Cell Res. 196, 33-39, 1991.
-
(1991)
Exp. Cell Res.
, vol.196
, pp. 33-39
-
-
Shay, J.W.1
Pereira-Smith, O.M.2
Wright, W.E.3
-
58
-
-
0028928036
-
Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase
-
SKAPEK, S.X., RHEE, J., SPICER, D.B., and LASSAR, A.B. Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase. Science 267, 1022-1024, 1995.
-
(1995)
Science
, vol.267
, pp. 1022-1024
-
-
Skapek, S.X.1
Rhee, J.2
Spicer, D.B.3
Lassar, A.B.4
-
59
-
-
0019133206
-
Loss of gene repression activity: A theory of cellular senescence
-
SMITH, J.R. and LUMPKIN, C.K. Loss of gene repression activity: A theory of cellular senescence. Mech. Ageing Dev. 13, 387-392, 1980.
-
(1980)
Mech. Ageing Dev.
, vol.13
, pp. 387-392
-
-
Smith, J.R.1
Lumpkin, C.K.2
-
60
-
-
0027295746
-
Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophoresis (CDGE)
-
SMITH-SORENSEN, B., GEBHARDT, M.C., KLOEN, P., McINTYRE, J., AGUILAR, F., CERUTTI, P., and BORRESEN, A.L. Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophoresis (CDGE). Hum. Mutat. 2, 274-285, 1993.
-
(1993)
Hum. Mutat.
, vol.2
, pp. 274-285
-
-
Smith-Sorensen, B.1
Gebhardt, M.C.2
Kloen, P.3
McIntyre, J.4
Aguilar, F.5
Cerutti, P.6
Borresen, A.L.7
-
61
-
-
0016158843
-
The phenomenon of premature chromosome condensation: Its relevance to basic and applied research
-
SPERLING, K. and RAO, P.N. The phenomenon of premature chromosome condensation: Its relevance to basic and applied research. Humangenetik 23, 235-258, 1974.
-
(1974)
Humangenetik
, vol.23
, pp. 235-258
-
-
Sperling, K.1
Rao, P.N.2
-
62
-
-
0018373626
-
Entry into S phase is inhibited in two immortal cell lines fused to senescent human diploid cells
-
STEIN, G.H. and YANISHEVSKY, R.M. Entry into S phase is inhibited in two immortal cell lines fused to senescent human diploid cells. Exp. Cell Res. 120, 155-165, 1979.
-
(1979)
Exp. Cell Res.
, vol.120
, pp. 155-165
-
-
Stein, G.H.1
Yanishevsky, R.M.2
-
63
-
-
0016647491
-
Chromosome changes during the in vitro ageing of MRC-5 human fibroblasts
-
THOMPSON, K.V.A. and HOLLIDAY, R. Chromosome changes during the in vitro ageing of MRC-5 human fibroblasts. Exp. Cell Res. 96, 1-6, 1975.
-
(1975)
Exp. Cell Res.
, vol.96
, pp. 1-6
-
-
Thompson, K.V.A.1
Holliday, R.2
-
64
-
-
0023712476
-
The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
-
WEINERT, T.A. and HARTWELL, L.H. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241, 317-322, 1988.
-
(1988)
Science
, vol.241
, pp. 317-322
-
-
Weinert, T.A.1
Hartwell, L.H.2
-
65
-
-
0028156003
-
Correlation between senescence and DNA repair in cells from young an old individuals and in premature aging syndromes
-
WEIRICH-SCHWAIGER, H., WEIRICH, H.G., GRUBER, B., SCHWEIGER, M., and HIRSCH-KAUFFMANN, M. Correlation between senescence and DNA repair in cells from young an old individuals and in premature aging syndromes. Mutat. Res. 316, 37-48, 1994.
-
(1994)
Mutat. Res.
, vol.316
, pp. 37-48
-
-
Weirich-Schwaiger, H.1
Weirich, H.G.2
Gruber, B.3
Schweiger, M.4
Hirsch-Kauffmann, M.5
-
66
-
-
0026682717
-
Telomere positional effects and the regulation of cellular senescence
-
WRIGHT, W.E., and SHAY, J.W. Telomere positional effects and the regulation of cellular senescence. Trends Genet. 8, 193-197, 1992.
-
(1992)
Trends Genet.
, vol.8
, pp. 193-197
-
-
Wright, W.E.1
Shay, J.W.2
-
67
-
-
0023036183
-
Abnormal regulation of uracil-DNA glycosylase induction during cell cycle and cell passage in Bloom's syndrome fibroblast
-
YAMAMOTO, Y. and FUJIWARA, Y. Abnormal regulation of uracil-DNA glycosylase induction during cell cycle and cell passage in Bloom's syndrome fibroblast. Carcinogenesis 7, 305-310, 1986.
-
(1986)
Carcinogenesis
, vol.7
, pp. 305-310
-
-
Yamamoto, Y.1
Fujiwara, Y.2
-
68
-
-
0023199825
-
Culture-age effect on uracil-DNA glycosylase activity in normal human skin fibroblasts
-
YAMAMOTO, Y. and FUJIWARA, Y. Culture-age effect on uracil-DNA glycosylase activity in normal human skin fibroblasts. J. Gerontol. 42, 470-475, 1987.
-
(1987)
J. Gerontol.
, vol.42
, pp. 470-475
-
-
Yamamoto, Y.1
Fujiwara, Y.2
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