Urea recycling: An aid to the excretion of potassium during antidiuresis

Nephron

Volumn 72, Issue 4, 1996, Pages 507-511

  Halperin, M L ^a   Gowrishankar, M ^a   Mallie, J P ^b   Sonnenberg, H ^c   Oh, M ^d  

^a St Michael s Hospital   (France)

^b UNIVERSITY HOSPITAL OF NANCY   (France)

^c UNIVERSITY OF TORONTO   (Canada)

^d SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

AIDS; Osmolality; Potassium; Sodium; Trimethoprim; Urea; Water

Indexed keywords

ALDOSTERONE; POTASSIUM; UREA; VASOPRESSIN;

ANTIDIURESIS; HYPERKALEMIA; INTERSTITIAL FLUID; KIDNEY COLLECTING TUBULE; KIDNEY INTERSTITIUM; KIDNEY MEDULLA; NEPHRON; OSMOLALITY; POTASSIUM EXCRETION; PRIORITY JOURNAL; SHORT SURVEY;

ANIMALS; CHLORIDES; DIURESIS; HUMANS; POTASSIUM; SODIUM; UREA;

EID: 0029921043     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000188930     Document Type: Article

References (32)

1. Kokko JP. Rector FCJ: Countercurrent multiplication system without active transport in the inner medulla. Kidney Ini 1972;2:214-223.
2. Jamison RL. Roy DR. Layton HE: Countercurrent mechanisms and its regulation: in Seldin DW. Giebisch GH (eds): Clinical Disturbances of Water Metabolism. New York, Raven Press, 1993. pp 99-118.
3. Stephenson JL: Central core model of the renal counterflow system. Kidney lnt 1972;2:85-94.
4. Knepper MA, Rector FC Jr: Urinary concentration and dilution: in Brenner BM. Rector FC Jr (eds): The Kidney. Philadelphia. Saunders. 1991, pp 445-482.
5. Rocha AS. Kokko JP: Permeability of medullary nephron segments to urea and water: Effect of vasopressin. Kidney Int 1974:6:379-387.
6. You G. Smith CP. Kanai Y, Lee WS. Stelzncr M. Hcdiger MA: Expression cloning and characterization of the vasopressin-regulated urea transporter. Nature 1993:365:844-847.
7. Morgan T. Berliner RW: Permeability of the loop of Hcnle, vasa recta, and collecting duct to water, urea, and sodium. Am J Physiol 1968; 215:108-115.
8. Morgan T, Sakai F, Berliner RW: In vitro permeability of medullary collecting ducts to water and urea. Am J Physiol 1968:214:574-581.
9. Sands JM, Nonoguchi H. Knepper MA: Vasopressin effect on urea and LLO transport in inner medullary collecting duct subsegments. Am J Physiol 1987;253:F823-F832.
10. Clapp JR: Renal tubular reabsorption of urea in normal and protein-depleted rats. Am J Physiol 1966:210:1304-1308.
11. Lassiter WE, Gottschalk CW, Mylle M: Micropuncture study of net transtubular movement of water and urea in non-diuretic mammalian kidney. Am J Physiol 1961:200:1139-1146.
12. Roch-Ramcl F. Peters G: Intrarenal urea and electrolyte concentrations as influenced by water diuresis and by hydrochlorothiazide. Eur J Pharmacol 1967; 1:124-139.
13. Checma-Dhadli S. Halpcrin ML: Diurnal excretion of nitrogen and sulphur after meals containing protein: Indications for postprandial synthesis of proteins. Can J Physiol Pharmacol 1993:71:120-129.
14. Roch-Ramcl F, Chomety F, Peters G: Urea concentrations in tubular fluid and in renal tissue of nondiuretic rats. Am J Physiol 1968;215: 429-438.
15. Ullrich KJ. Schmidt-Nielsen B. O'Dell R. Peh-ling G. Gottschalk CW. Lassiter WE. Mylle M: Micropuncture study of composition of proximal and distal tubular fluid in rat kidney. Am J Physiol 1963:204:527-531.
16. Danielson RA. Schmidt-Nielsen B, Hohbergcr C: Micropuncture study of the regulation of urea excretion by the collecting ducts in rats on high and low protein diets; in Schmidt-Nielsen B. Kerr BNS (eds): Urea and the Kidney. Amsterdam. Excerpta Medica, 1970. pp 375-384.
17. Walker A, Bolt P. Oliver J. MacDowell M: The collection and analysis of fluid from single nephrons of the mammalian kidney. Am J Physiol 1941:134:580-595.
18. Wirz, H: Der osmotischc Druck in den cortica-lcn Tubuli der Rattenniere. Helv Physiol Pharmacol Acta 1956:14:353-362.
19. Sonnenberg H: Proximal and distal tubular function in salt deprived and in salt loaded DOCA escaped rats. J Clin Invest !973;52: 263-272.
20. Seney FD Jr. Pcrsson EG, Wright FS: Modification of tubuloglomerular feedback signal by dietary protein. Am J Physiol 1987:252:F83-F90.
21. Robertson GL: Physiology of ADH secretion. Kidney Int 1987;32:S-20-S-26.
22. Sonnenberg H: Medullary collecting duct function in antidiuretic and in salt or water diuretic rats. AnterJ Physiol 1974;226:501-506.
23. Kamel KS. Quaggin S, Scheich A, Halperin ML: Disorders of potassium homeostasis: An approach based on pathophysiology. Am J Kidney Dis 1994:24:597-613.
24. Steele A, deVcber H, Quaggin SE, Scheich A. Ethier J, Halperin ML: What is responsible for the diurnal variation in potassium excretion? Am J Physiol 1994;36:R554-R560.
25. Wright FS, Giebisch G: Regulation of potassium excretion; in Seldin DW, Giebisch G (eds): The Kidney: Physiology and Pathophysiology. New York. Raven Press. 1992. pp 2209-2217.
26. Rossier BC. Palmer LG: Mechanisms of aldosterone action on sodium and potassium transport: in Seldin DW, Giebisch G (eds): The Kidney: Physiology and Pathophysiology. New York. Raven Press. 1992, pp 1373-1409.
27. Velazquez H. Perazclla MA. Wright FS. Ellison DH: Renal mechanism of trimethoprim-induced hyperkalemia. Ann Intern Med 1993; 119:295-301.
28. Choi MJ. Fernandez PC. Patnaik A, Coupaye-Gcrard B, D'Andrea D. Zerlip H, Klcyman TR: Trimethoprim induced hyperkalemia in a patient with AIDS. N Engl J Med 1993:328: 703-706.
29. Schreiber M. Halperin ML: Urea excretion rate as a contributor to trimethoprim-induced hyperkalemia. Ann Intern Med 1994:120:166-167.
30. Field MJ, Giebisch GJ: Hormonal control of renal potassium excretion. Kidney lnt 1985:27: 379-387.
31. Ethier JH. Kamel KS. Magner PO. Leraann JJ. Halperin ML: The transtubular potassium concentration in patients with hypokalemia and hyperkalemia. Am J Kidney Dis 1990:15:309-315.
32. Halperin ML. Goldstein MB: Fluid. Electrolyte and Acid-Base Physiology: A Problem-Base Approach. Philadelphia. Saunders, 1994.