Enhanced platelet thromboxane synthesis and reduced macrophage-dependent fibrinolytic activity related to oxidative stress in oral contraceptive-treated female rats

Atherosclerosis

Volumn 121, Issue 2, 1996, Pages 205-216

  Durand, Philippe ^a   Blache, Denis ^a  

^a UNIVERSITÉ DE BOURGOGNE   (France)

Author keywords

Arachidonic acid; Fatty acid composition; Fibrinolytic activity; macrophage (rat); Oral contraceptives; Oxidative stress; Platelet; Thromboxane

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ARACHIDONIC ACID; ETHINYLESTRADIOL PLUS LYNESTRENOL; ORAL CONTRACEPTIVE AGENT; THROMBOXANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; FIBRINOLYSIS; HEART INFARCTION; MACROPHAGE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STROKE; THROMBOCYTE; THROMBOEMBOLISM;

EID: 0029920984     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9150(95)05720-X     Document Type: Article

References (47)

1. Royal College of General Practioner', Oral contraception study. Mortality among oral-contraceptive users. Lancet 1977;2:727.
2. Leaf DA, Bland D, Schaad D, Neighbor WE, Scott CS. Oral contraceptive use and coronary risk factors in women. Am J Med Sci 1991;301:365.
3. Kaplan NM. Cardiovascular complications of oral contraceptives. Ann Rev Med 1978;29:31.
4. Meade TW. Risks and mechanisms of cardiovascular events in users of oral contraceptives. Am J Obstet Gynecol 1988;158:1646.
5. Ernst E. Oral contraceptives, fibrinogen and cardiovascular risk. Atherosclerosis 1992;93:1.
6. Beller FK, Ebert C. Effects of oral contraceptives on blood coagulation. A review, Obstet Gynecol Surv 1985;40:425.
7. Inauen W, Baumgartner HR, Haeberli A, Straub PW. Excessive deposition of fibrin, platelets and platelet thrombi on vascular subendothelium during contraceptive drug treatment. Thromb Haemost 1987;57:306.
8. Ciavatti M, Davenas E, Blache D, Renaud S. Vitamin E prevents the platelet abnormalities induced by estrogen in rat. Contraception 1984;30:279.
9. Ciavatti M, Davenas E, Blache D, Monnier A, Renaud S. Biosynthesis of platelet lipids in relation to aggregation in women using oral contraceptives. Contraception 1982;25:629.
10. Pan JQ, Hall ER, Wu KK. Alteration of platelet responses to metabolites or arachidonic acid by oral contraceptives. Br J Haematol 1984;58:317.
11. Skjaerlund JM, Gallon L, Subbiah MTR. Effect of ethinyl estradiol on arachidonic acid incorporation, release and conversion to prostaglandins in rabbit platelets. Biochem Med 1983;30:357.
12. 2 in humans. Am J Obstet Gynecol 1982;142:573.
13. Jespersen J, Kluft C. Inhibition of tissue-type plasminogen activator in plasma of women using oral contraceptives and in normal women during a menstrual cycle. Thromb Haemost 1986;55:388.
14. Daly L, Bonnar J. Comparative studies of 30 mg ethinyl estradiol combined with gestodene and desogestrel on blood coagulation, flbrinolysis and platelets. Am J Obstet Gynecol 1990;163:430.
15. Campbell SJ, Mackie IJ, Robinson GE, Machin SJ. Contact factor mediated fibrinolysis is increased by the combined oral contraceptive pill. Br J Obstet Gynaecol 1993;100:79.
16. Saksela O. Plasminogen activation and regulation of pericellular proteolysis. Biochim Biophys Acta 1985;823:35.
17. Vassalli J-D, Wohlwend A, Belin D. Urokinase-catalyzed plasminogen activation at the monocyte/macrophage cell surface: a localized and regulated proteolytic system. Curr Top Microbiol Immunol 1992;181:65.
18. Fehily AMA, Dickerson JWT, Meade BW, Ellis FR. Plasma and erythrocyte membrane fatty acids in oral contraceptive users. Clin Chim Acta 1982;120:41.
19. Coller BS. Platelets and thrombolytic therapy. N. Engl J Med 1990;322:33.
20. Bode C, Meinhardt G, Runge MS, Freitag M, Nordt T, Arens M, Newell JB, Kübier W, Haber E. Platelet-targeted fibrinolysis enhances clot lysis and inhibits platelet aggregation. Circulation 1991;84:805.
21. 2+ : effects of calcium antagonists. Thromb Res 1987;46:779.
22. Blache D, Ciavatti M, Ojeda C. The effect of calcium channel blockers on blood platelet function, especially calcium uptake. Biochim Biophys Acta 1987;923:401.
23. Born GVR. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 1962;194:927.
24. 2. Biochim Biophys Acta 1987;921:541.
25. Polette A, Blache D. Effect of vitamin E on acute iron load-potentiated aggregation, secretion, calcium uptake and thromboxane biosynthesis in rat platelets. Atherosclerosis 1992;96:171.
26. Bills TK, Smith JB, Silver MJ. Selective release of arachidonic acid from the phospholipids of human platelets in response to thrombin. J Clin Invest 1977;60:1.
27. Unkeless JC, Gordon S, Reich E. Secretion of plasminogen activator by stimulated macrophages. J Exp Biol 1974;139:834.
28. Drapier J-C, Tenu J-P, Lemaire G, Petit J-F. Regulation of plasminogen activator secretion in mouse peritoneal macrophages. I. - Role of serum studied by a new spectrophotometric assay for plasminogen activators. Biochimie 1979;61:463.
29. Freyria AM, Paul J, Belleville J, Broyer P, Eloy R. Rat peritoneal macrophage procoagulant and fibrinolytic activities: an expression of the local inflammatory response. Comp Biochem Physiol [A] 1991;99A:517.
30. Folch J, Lees M, Sloane-Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957;226:497.
31. Morrisson WR, Smith LM. Preparation of fatty acid methyl esters and dimethyl acetates from lipids with boron fluoride methanol. J Lipid Res 1964;5:600.
32. Polette A, Durand P, Floccard B, Blache D. A method for specific analysis of free fatty acids in biological samples by capillary gas chromatography. Anal Biochem 1992;206:241.
33. Blache D. Involvement of hydrogen and lipid peroxides in the acute tobacco smoking-induced platelet hyperactivity. Am J Physiol 1995;268 H679.
34. El-Saadani M, Esterbauer H, El-Sayed M, Goher M, Nassar AY, Jürgens G. A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent. J Lipid Res 1989;30:627.
35. Blache D, Prost M, Raffi J. In vitro biological test of resistance to oxidation: application to identification of irradiated food. In: Anonymous (ed). Potential New Methods of Detection of Irradiated Food, Commission of the European Communities. Luxembourg, 1991;105-116.
36. Blache D, Prost M. Free radical attack: biological test for human resistance capability. In: Ponnamperum C, Gehrke CW. (eds). Proceedings of the IX College Park Colloquium on Chemical Evolution: A Lunar-Based Chemical Analysis Laboratory (LBCAL), NASA. Washington, 1992;82-98.
37. Norris LA, Bonnar J. The in vitro effect of aspirin on increased whole blood platelet aggregation in oral contraceptive users. Thromb Res 1994;74:309.
38. 2 levels due to oral contraceptives. Contraception 1995;51:53.
39. Hadjigapiou C, Spector AA. 12-hydroxyeicosatetraenoic acid reduces protacyclin production by endothelial cells. Prostaglandins 1986;31:1135.
40. Meade TW, Vickers MV, Thompson SG, Stirling Y, Haines AP, Miller GJ. Epidemiological characterics of platelet aggregability. Br Med J 1985;290:428.
41. Nowak J Murray JJ, Oates JA, FitzGerald GA. Biochemical evidences of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarette. Circulation 1987;76:6.
42. Warso MA, Lands WEM. Pathophysiologic modulation of arachidonate metabolism. Clin Physiol Biochem 1984;2:70.
43. Blache D, Bouthillier D, Davignon J. Acute influence of smoking on platelet behaviour endothelium and plasma lipids and normalization by Aspirin. Atherosclerosis 1992;93:179.
44. Ciavatti M, Blache D, Renaud S. Dietary fats modulate hormonal contraceptive induced changes in platelet aggregation, composition and lipid biosynthesis in female rats. Nutr Res 1987;7:589.
45. Ciavatti M, Blache D, Renaud S. Hormonal contraceptive increases plasma lipid peroxides in female rats: relationship to platelet aggregation and lipid biosynthesis. Arteriosclerosis 1989;9:84.
46. Liehr JG, Roy D. Free radical generation by redox cycling of estrogens. Free Rad Biol Med 1990;8:415.
47. 3) is formed in human platelets after dietary eicosapentaenoic acid. Biochem Biophys Res Commun 1983;116:1091.