메뉴 건너뛰기




Volumn 104, Issue 2, 1996, Pages 81-93

Predictors of joint damage in rheumatoid arthritis

Author keywords

Biological markers; Bone cartilage; Joint damage; Synovium

Indexed keywords

ACUTE PHASE PROTEIN; AGGRECAN; COLLAGEN TYPE 2; COLLAGEN TYPE 3; HYALURONIC ACID; NEOPTERIN;

EID: 0029920867     PISSN: 09034641     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1699-0463.1996.tb00691.x     Document Type: Review
Times cited : (38)

References (103)
  • 1
    • 0025274640 scopus 로고
    • Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis
    • Arend, W. P. & Dayer, J.-M.: Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis. Rheum. 33: 305-315, 1990.
    • (1990) Arthritis. Rheum. , vol.33 , pp. 305-315
    • Arend, W.P.1    Dayer, J.-M.2
  • 2
    • 0029016084 scopus 로고
    • Role of interferons and other cytokines in the regulation of the immune response
    • Belardelli, F.: Role of interferons and other cytokines in the regulation of the immune response. APMIS 103: 161-179, 1995.
    • (1995) APMIS , vol.103 , pp. 161-179
    • Belardelli, F.1
  • 3
    • 0024852024 scopus 로고
    • A longitudinal study of the leukocyte protein L1 as an indicator of disease activity in patients with rheumatoid arthritis
    • Berntzen, H. B., Munthe, E. & Fagerhol, M. K.: A longitudinal study of the leukocyte protein L1 as an indicator of disease activity in patients with rheumatoid arthritis. J. Rheumatol. 16: 1416-1420, 1989.
    • (1989) J. Rheumatol. , vol.16 , pp. 1416-1420
    • Berntzen, H.B.1    Munthe, E.2    Fagerhol, M.K.3
  • 5
    • 0027992161 scopus 로고
    • Validity of acute phase proteins as markers of disease activity
    • Blackburn Jr., W. D.: Validity of acute phase proteins as markers of disease activity. J. Rheumatol. 21 (Suppl. 42): 9-13, 1994.
    • (1994) J. Rheumatol. , vol.21 , Issue.42 SUPPL. , pp. 9-13
    • Blackburn Jr., W.D.1
  • 6
    • 0026533382 scopus 로고
    • Combination therapy in rheumatoid arthritis
    • Boerbooms, A.: Combination therapy in rheumatoid arthritis. J. Rheumatol. 19: 500-501, 1992.
    • (1992) J. Rheumatol. , vol.19 , pp. 500-501
    • Boerbooms, A.1
  • 7
    • 0028094409 scopus 로고
    • Sulfate metabolism is abnormal in patients with rheumatoid arthritis. Confirmation by in vivo biochemical findings
    • Bradley, H., Gough, A., Sokhi, R. S., Hassell, A., Waring, R. & Emery, P.: Sulfate metabolism is abnormal in patients with rheumatoid arthritis. Confirmation by in vivo biochemical findings. J. Rheumatol. 21: 1192-1196, 1994.
    • (1994) J. Rheumatol. , vol.21 , pp. 1192-1196
    • Bradley, H.1    Gough, A.2    Sokhi, R.S.3    Hassell, A.4    Waring, R.5    Emery, P.6
  • 8
    • 0024713709 scopus 로고
    • A pessimistic view of serologic markers for diagnosis and management of osteoarthritis: Biochemical, immunologic, and clinicopathologic barriers
    • Brandt, K. D.: A pessimistic view of serologic markers for diagnosis and management of osteoarthritis: biochemical, immunologic, and clinicopathologic barriers. J. Rheumatol. 16 (Suppl. 18): 39-42, 1989.
    • (1989) J. Rheumatol. , vol.16 , Issue.18 SUPPL. , pp. 39-42
    • Brandt, K.D.1
  • 9
    • 0026652590 scopus 로고
    • Calprotectin (L1) in patients with rheumatoid arthritis and in healthy controls: Relation to clinical and laboratory parameters of disease activity
    • Brun, J., Haga, H. J., Boe, E., Kallay, I., Lekven, C., Berntzen, H. B. & Fagerhol, M. K.: Calprotectin (L1) in patients with rheumatoid arthritis and in healthy controls: relation to clinical and laboratory parameters of disease activity. J. Rheumatol. 19: 859-862, 1992.
    • (1992) J. Rheumatol. , vol.19 , pp. 859-862
    • Brun, J.1    Haga, H.J.2    Boe, E.3    Kallay, I.4    Lekven, C.5    Berntzen, H.B.6    Fagerhol, M.K.7
  • 10
    • 0020529209 scopus 로고
    • Identification of a monoclonal antibody that specifically recognized corneal and skeletal keratin sulfate. Monoclonal antibodies to cartilage proteoglycan
    • Caterson, B., Christner, J. E. & Baker, J. R.: Identification of a monoclonal antibody that specifically recognized corneal and skeletal keratin sulfate. Monoclonal antibodies to cartilage proteoglycan. J. Biol. Chem. 258: 8848-8854, 1983.
    • (1983) J. Biol. Chem. , vol.258 , pp. 8848-8854
    • Caterson, B.1    Christner, J.E.2    Baker, J.R.3
  • 11
    • 0027220527 scopus 로고
    • Increased levels of circulating intercellular adhesion molecule 1 in the sera of patients with rheumatoid arthritis
    • Cush, J. J., Rothlein, R., Lindsley, H. B., Mainolfi, E. A. & Lipsky, P. E.: Increased levels of circulating intercellular adhesion molecule 1 in the sera of patients with rheumatoid arthritis. Arthritis Rheum. 36: 1098-1102, 1993.
    • (1993) Arthritis Rheum. , vol.36 , pp. 1098-1102
    • Cush, J.J.1    Rothlein, R.2    Lindsley, H.B.3    Mainolfi, E.A.4    Lipsky, P.E.5
  • 12
    • 0029078733 scopus 로고
    • Treatment of early rheumatoid arthritis: A review of current and future concepts and therapy
    • Dawes, P. T. & Fowler, P. D.: Treatment of early rheumatoid arthritis: a review of current and future concepts and therapy. Clin. Exp. Rheumatol. 13: 381-394, 1995.
    • (1995) Clin. Exp. Rheumatol. , vol.13 , pp. 381-394
    • Dawes, P.T.1    Fowler, P.D.2
  • 13
    • 0027316221 scopus 로고
    • Immunoassay of pyridinoline crosslink excretion in normal adults and in Paget's disease
    • Delmas, P. D., Gineyts, E., Bertholin, A., Garnero, P. & Marchard, F.: Immunoassay of pyridinoline crosslink excretion in normal adults and in Paget's disease. J. Bone Miner. Res. 8: 643-648, 1993.
    • (1993) J. Bone Miner. Res. , vol.8 , pp. 643-648
    • Delmas, P.D.1    Gineyts, E.2    Bertholin, A.3    Garnero, P.4    Marchard, F.5
  • 14
    • 0026676874 scopus 로고
    • Utility of type I procollagen propeptide assays for assessing abnormalities in metabolic bone disease
    • Ebeling, P. R., Peterson, J. M. & Riggs, R. L.: Utility of type I procollagen propeptide assays for assessing abnormalities in metabolic bone disease. J. Bone Miner. Res. 7: 1243-1250, 1992.
    • (1992) J. Bone Miner. Res. , vol.7 , pp. 1243-1250
    • Ebeling, P.R.1    Peterson, J.M.2    Riggs, R.L.3
  • 15
    • 0029068941 scopus 로고
    • Functional impairment and disability in early rheumatoid arthritis-development over 5 years
    • Eberhardt, K. B. & Fex, E.: Functional impairment and disability in early rheumatoid arthritis-development over 5 years. J. Rheumatol. 22: 1037-1042, 1995.
    • (1995) J. Rheumatol. , vol.22 , pp. 1037-1042
    • Eberhardt, K.B.1    Fex, E.2
  • 16
    • 0023756439 scopus 로고
    • Functional assessment of early rheumatoid arthritis
    • Eberhardt, K., Svensson, B. & Moritz, U.: Functional assessment of early rheumatoid arthritis. Br. J. Rheumatol. 27: 364-371, 1988.
    • (1988) Br. J. Rheumatol. , vol.27 , pp. 364-371
    • Eberhardt, K.1    Svensson, B.2    Moritz, U.3
  • 17
    • 0025166148 scopus 로고
    • Early rheumatoid arthritis - Onset, course, and outcome over 2 years
    • Eberhardt, K. B., Rydgren, L. C., Pettersson, H. & Wollheim, F. A.: Early rheumatoid arthritis - onset, course, and outcome over 2 years. Rheumatol. Int. 10: 135-142, 1990a.
    • (1990) Rheumatol. Int. , vol.10 , pp. 135-142
    • Eberhardt, K.B.1    Rydgren, L.C.2    Pettersson, H.3    Wollheim, F.A.4
  • 18
    • 0025054018 scopus 로고
    • Disease activity and joint damage progression in early rheumatoid arthritis - Relation to IgG, IgA, and IgM rheumatoid factor
    • Eberhardt, K. B., Truedsson, L., Pettersson, H., Svensson, B., Stigsson, L., Eberhardt, J. L. & Wollheim, F. A.: Disease activity and joint damage progression in early rheumatoid arthritis - relation to IgG, IgA, and IgM rheumatoid factor. Ann. Rheum. Dis. 49: 906-909, 1990b.
    • (1990) Ann. Rheum. Dis. , vol.49 , pp. 906-909
    • Eberhardt, K.B.1    Truedsson, L.2    Pettersson, H.3    Svensson, B.4    Stigsson, L.5    Eberhardt, J.L.6    Wollheim, F.A.7
  • 20
    • 0030070401 scopus 로고    scopus 로고
    • Association of HLA DRB and DQB genes with 2 and 5 year outcome in rheumatoid arthritis
    • Eberhardt, K. B., Fex, E., Johnson U. & Wollheim, F. A.: Association of HLA DRB and DQB genes with 2 and 5 year outcome in rheumatoid arthritis. Ann. Rheum. Dis. 55: 34-39, 1996.
    • (1996) Ann. Rheum. Dis. , vol.55 , pp. 34-39
    • Eberhardt, K.B.1    Fex, E.2    Johnson, U.3    Wollheim, F.A.4
  • 21
    • 0026729003 scopus 로고
    • Genetic factors influencing the outcome of early arthritis - The role of sulphoxidation status
    • Emery, P., Bradley, H., Arthur, V., Tunn, E. & Waring, R.: Genetic factors influencing the outcome of early arthritis - the role of sulphoxidation status. Br. J. Rheumatol. 31: 449-451, 1992.
    • (1992) Br. J. Rheumatol. , vol.31 , pp. 449-451
    • Emery, P.1    Bradley, H.2    Arthur, V.3    Tunn, E.4    Waring, R.5
  • 22
    • 0021964063 scopus 로고
    • Circulating hyaluronate in rheumatoid arthritis: Relationship to inflammatory activity and the effect of corticosteroid therapy
    • Engström-Laurent, A. & Hällgren, R.: Circulating hyaluronate in rheumatoid arthritis: Relationship to inflammatory activity and the effect of corticosteroid therapy. Ann. Rheum. Dis. 44: 83-88, 1985.
    • (1985) Ann. Rheum. Dis. , vol.44 , pp. 83-88
    • Engström-Laurent, A.1    Hällgren, R.2
  • 23
    • 0023612398 scopus 로고
    • Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients. Relationship to synovitis mass and morning stiffness
    • Engström-Laurent, A. & Hällgren, R.: Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients. Relationship to synovitis mass and morning stiffness. Arthritis Rheum. 30: 1333-1338, 1987.
    • (1987) Arthritis Rheum. , vol.30 , pp. 1333-1338
    • Engström-Laurent, A.1    Hällgren, R.2
  • 25
    • 0026726724 scopus 로고
    • Increased serum concentrations of cartilage oligomeric matrix protein. Prognostic marker in early rheumatoid arthritis
    • Forslind, K., Eberhardt, K., Jonson, A. & Saxne, T.: Increased serum concentrations of cartilage oligomeric matrix protein. Prognostic marker in early rheumatoid arthritis. Br. J. Rheumatol. 31: 593-598, 1992.
    • (1992) Br. J. Rheumatol. , vol.31 , pp. 593-598
    • Forslind, K.1    Eberhardt, K.2    Jonson, A.3    Saxne, T.4
  • 26
    • 0028061748 scopus 로고
    • Genetic typing of patients with inflammatory arthritis at presentation can be used to predict outcome
    • Gough, A., Faint, J., Salmon, M., Hassel, A., Wordsworth, P., Piling, D., Birley, A. & Emery, P.: Genetic typing of patients with inflammatory arthritis at presentation can be used to predict outcome. Arthritis Rheum. 37: 1166-1170, 1994a.
    • (1994) Arthritis Rheum. , vol.37 , pp. 1166-1170
    • Gough, A.1    Faint, J.2    Salmon, M.3    Hassel, A.4    Wordsworth, P.5    Piling, D.6    Birley, A.7    Emery, P.8
  • 27
    • 0028305241 scopus 로고
    • Generalised bone loss in patients with early rheumatoid arthritis
    • Gough, A. K. S., Lilley, J., Eyre, S., Holder, R. L. & Emery, P.: Generalised bone loss in patients with early rheumatoid arthritis. Lancet 344: 23-27, 1994b.
    • (1994) Lancet , vol.344 , pp. 23-27
    • Gough, A.K.S.1    Lilley, J.2    Eyre, S.3    Holder, R.L.4    Emery, P.5
  • 28
    • 0028147482 scopus 로고
    • Excretion of pyridinium crosslinks correlates with disease activity and appendicular bone loss in early rheumatoid arthritis
    • Gough, A. K. S., Peel, N. F. A., Eastell, R., Holder, R. L., Lilley, J. & Emery, P.: Excretion of pyridinium crosslinks correlates with disease activity and appendicular bone loss in early rheumatoid arthritis. Ann. Rheum. Dis. 53: 14-17, 1994c.
    • (1994) Ann. Rheum. Dis. , vol.53 , pp. 14-17
    • Gough, A.K.S.1    Peel, N.F.A.2    Eastell, R.3    Holder, R.L.4    Lilley, J.5    Emery, P.6
  • 29
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • Gregersen, P. K., Silver, J. & Winchester, R. J.: The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum. 30: 1205-1213, 1987.
    • (1987) Arthritis Rheum. , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 30
    • 0027239526 scopus 로고
    • Viscosity of plasma and blood in rheumatoid arthritis
    • Gudmundsson, M. & Bjelle, A.: Viscosity of plasma and blood in rheumatoid arthritis. Br. J. Rheumatol. 32: 774-779, 1993.
    • (1993) Br. J. Rheumatol. , vol.32 , pp. 774-779
    • Gudmundsson, M.1    Bjelle, A.2
  • 31
    • 0027773069 scopus 로고
    • Increased type I collagen degradation correlates with disease severity in rheumatoid arthritis
    • Hakala, M., Risteli, L., Manelius, J., Nieminen, P. & Risteli, J.: Increased type I collagen degradation correlates with disease severity in rheumatoid arthritis. Ann. Rheum. Dis. 52: 866-869, 1993.
    • (1993) Ann. Rheum. Dis. , vol.52 , pp. 866-869
    • Hakala, M.1    Risteli, L.2    Manelius, J.3    Nieminen, P.4    Risteli, J.5
  • 35
    • 0029011046 scopus 로고
    • Autoimmune response to the spliceosome. An immunologic link between rheumatoid arthritis, mixed connective tissue disease, and systemic lupus erythematosus
    • Hassfeld, W., Steiner, G., Studnicka-Benke, A., Skriner, K., Graninger, W., Fischer, I. & Smolen, J. S.: Autoimmune response to the spliceosome. An immunologic link between rheumatoid arthritis, mixed connective tissue disease, and systemic lupus erythematosus. Arthritis Rheum. 38: 777-785, 1995.
    • (1995) Arthritis Rheum. , vol.38 , pp. 777-785
    • Hassfeld, W.1    Steiner, G.2    Studnicka-Benke, A.3    Skriner, K.4    Graninger, W.5    Fischer, I.6    Smolen, J.S.7
  • 36
    • 0024370924 scopus 로고
    • Osteocalcin and matrix G1a protein: Vitamin K-dependent proteins in bone
    • Hauschka, P. V., Lian, J. B., Cole, D. E. C. & Gundberg, C. M.: Osteocalcin and matrix G1a protein: vitamin K-dependent proteins in bone. Physiol. Rev. 69: 990-1047, 1989.
    • (1989) Physiol. Rev. , vol.69 , pp. 990-1047
    • Hauschka, P.V.1    Lian, J.B.2    Cole, D.E.C.3    Gundberg, C.M.4
  • 37
    • 0002352152 scopus 로고
    • Cartilage matrix proteins
    • Kuettner, K. et al. (Eds.): Raven Press, New York
    • Heinegård, D. & Pimentel, E. R.: Cartilage matrix proteins. In: Kuettner, K. et al. (Eds.): Articular Cartilage and Osteoarthritis. Raven Press, New York 1992, pp. 95-111.
    • (1992) Articular Cartilage and Osteoarthritis , pp. 95-111
    • Heinegård, D.1    Pimentel, E.R.2
  • 38
    • 0002944264 scopus 로고
    • The antiperinuclear factor (APF) and antikeratin antibodies (AKA) in rheumatoid arthritis
    • Smolen, J. S., Kalden, J. R. & Maini, R. N. (Eds.): Springer-Verlag, Berlin Heidelberg
    • Hoet, R. M. & van Venrooij, W. J.: The antiperinuclear factor (APF) and antikeratin antibodies (AKA) in rheumatoid arthritis. In: Smolen, J. S., Kalden, J. R. & Maini, R. N. (Eds.): Rheumatoid Arthritis. Recent Research Advances. Springer-Verlag, Berlin Heidelberg 1992, pp. 299-318.
    • (1992) Rheumatoid Arthritis. Recent Research Advances , pp. 299-318
    • Hoet, R.M.1    Van Venrooij, W.J.2
  • 39
    • 0023870280 scopus 로고
    • Serum amino terminal type III procollagen peptide and serum hyaluronan in rheumatoid arthritis: Relation to clinical and serological parameters of inflammation during 8 and 24 months treatment with levamisole, penicillamine or azathioprine
    • Horslev-Petersen, K., Bendtzen, K. D., Engström-Laurent, A. et al.: Serum amino terminal type III procollagen peptide and serum hyaluronan in rheumatoid arthritis: Relation to clinical and serological parameters of inflammation during 8 and 24 months treatment with levamisole, penicillamine or azathioprine. Ann. Rheum. Dis. 47: 116-126, 1988.
    • (1988) Ann. Rheum. Dis. , vol.47 , pp. 116-126
    • Horslev-Petersen, K.1    Bendtzen, K.D.2    Engström-Laurent, A.3
  • 40
    • 0027981704 scopus 로고
    • Clinical utility and serological connections of anti-RA33 antibodies in systemic lupus erythematosus
    • Isenberg, D. A., Steiner, G. & Smolen, J. S.: Clinical utility and serological connections of anti-RA33 antibodies in systemic lupus erythematosus. J. Rheumatol. 21: 1260-1263, 1994.
    • (1994) J. Rheumatol. , vol.21 , pp. 1260-1263
    • Isenberg, D.A.1    Steiner, G.2    Smolen, J.S.3
  • 42
    • 0025013236 scopus 로고
    • Serum baseline hyaluronate and disease activity in rheumatoid arthritis
    • Konttinen, Y. T., Saari, H., Honkanen, V. E. A. et al.: Serum baseline hyaluronate and disease activity in rheumatoid arthritis. Clin. Chim. Acta 193: 39-48, 1990.
    • (1990) Clin. Chim. Acta , vol.193 , pp. 39-48
    • Konttinen, Y.T.1    Saari, H.2    Honkanen, V.E.A.3
  • 43
    • 0023941927 scopus 로고
    • The relation of radiographic changes to serum acute-phase proteins and rheumatoid factor in 200 patients with rheumatoid arthritis
    • Larsen, A.: The relation of radiographic changes to serum acute-phase proteins and rheumatoid factor in 200 patients with rheumatoid arthritis. Scand. J. Rheumatol. 17: 123-129, 1988.
    • (1988) Scand. J. Rheumatol. , vol.17 , pp. 123-129
    • Larsen, A.1
  • 44
    • 0027398884 scopus 로고
    • Epidemiological approaches to the immunogenetics of autoimmune rheumatic disease
    • MacGregor, A. & Silman, A.: Epidemiological approaches to the immunogenetics of autoimmune rheumatic disease. Ann. Rheum. Dis. 52: 310-313, 1993.
    • (1993) Ann. Rheum. Dis. , vol.52 , pp. 310-313
    • MacGregor, A.1    Silman, A.2
  • 45
  • 46
    • 0028090359 scopus 로고
    • Intercellular adhesion molecule-1 is a cell surface receptor for hyaluronan
    • McCourt, P. A. G., Ek, B., Forsberg, N. & Gustafson, S.: Intercellular adhesion molecule-1 is a cell surface receptor for hyaluronan. J. Biol. Chem. 269: 30081-30084, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30081-30084
    • McCourt, P.A.G.1    Ek, B.2    Forsberg, N.3    Gustafson, S.4
  • 47
    • 0025033911 scopus 로고
    • Radioimmunoassay of the carboxyterminal propeptide of human type I procollagen
    • Melkko, J., Niemi, S., Risteli, L. & Risteli, J.: Radioimmunoassay of the carboxyterminal propeptide of human type I procollagen. Clin. Chem. 36: 1238-1332, 1990.
    • (1990) Clin. Chem. , vol.36 , pp. 1238-1332
    • Melkko, J.1    Niemi, S.2    Risteli, L.3    Risteli, J.4
  • 48
    • 0028179218 scopus 로고
    • Clearance of NH2-terminal propeptides of types I and III procollagen is a physiological function of the scavenger receptor in liver endothelial cells
    • Melkko, J., Hellevik, T., Risteli, L., Risteli, J. & Smedrod, B.: Clearance of NH2-terminal propeptides of types I and III procollagen is a physiological function of the scavenger receptor in liver endothelial cells. J. Exp. Med. 179: 405-412, 1994.
    • (1994) J. Exp. Med. , vol.179 , pp. 405-412
    • Melkko, J.1    Hellevik, T.2    Risteli, L.3    Risteli, J.4    Smedrod, B.5
  • 49
    • 0027397839 scopus 로고
    • Balance of synovial fluid IL-1β and IL-1 receptor antagonist and recovery from Lyme arthritis
    • Miller, L. C., Lynch, E. A., Isa, S., Logan, J. W., Dinarello, C. D. & Steere, A. C.: Balance of synovial fluid IL-1β and IL-1 receptor antagonist and recovery from Lyme arthritis. Lancet 341: 146-148, 1993.
    • (1993) Lancet , vol.341 , pp. 146-148
    • Miller, L.C.1    Lynch, E.A.2    Isa, S.3    Logan, J.W.4    Dinarello, C.D.5    Steere, A.C.6
  • 50
    • 0029154760 scopus 로고
    • Even low-grade synovitis significantly accelerates the clearance of protein from the canine knee. Implications for measurement of synovial fluid "markers" of osteoarthritis
    • Myers, S. L., Brandt, K. D. & Eilam, O.: Even low-grade synovitis significantly accelerates the clearance of protein from the canine knee. Implications for measurement of synovial fluid "markers" of osteoarthritis. Arthritis Rheum. 38: 1085-1091, 1995.
    • (1995) Arthritis Rheum. , vol.38 , pp. 1085-1091
    • Myers, S.L.1    Brandt, K.D.2    Eilam, O.3
  • 51
    • 0025350514 scopus 로고
    • Cytidine deaminase activity in synovial fluid of patients with rheumatoid arthritis: Relation to lactoferrin, acidosis, and cartilage proteoglycan release
    • Månsson, B., Geborek, P., Saxne, T. & Björnsson, S.: Cytidine deaminase activity in synovial fluid of patients with rheumatoid arthritis: relation to lactoferrin, acidosis, and cartilage proteoglycan release. Ann. Rheum. Dis. 49: 594-597, 1990.
    • (1990) Ann. Rheum. Dis. , vol.49 , pp. 594-597
    • Månsson, B.1    Geborek, P.2    Saxne, T.3    Björnsson, S.4
  • 52
    • 0028934327 scopus 로고
    • Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism
    • Månsson, B., Carey, D., Alini, M., Ionescu, M., Rosenberg, L. C., Poole, A. R., Heinegård, D. & Saxne, T.: Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism. J. Clin. Invest. 95: 1071-1077, 1995.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1071-1077
    • Månsson, B.1    Carey, D.2    Alini, M.3    Ionescu, M.4    Rosenberg, L.C.5    Poole, A.R.6    Heinegård, D.7    Saxne, T.8
  • 53
    • 0001588341 scopus 로고
    • Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence
    • Oldberg, Å., Franzén, A. & Heinegård, D.: Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence. Proc. Natl. Acad. Sci. USA 83: 8819-8823, 1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8819-8823
    • Oldberg, Å.1    Franzén, A.2    Heinegård, D.3
  • 54
    • 0026499722 scopus 로고
    • COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins
    • Oldberg, A., Antonsson, P., Lindblom, K. & Heinegård, D.: COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins. J. Biol. Chem. 207: 22346-22350, 1992.
    • (1992) J. Biol. Chem. , vol.207 , pp. 22346-22350
    • Oldberg, A.1    Antonsson, P.2    Lindblom, K.3    Heinegård, D.4
  • 55
    • 0025762251 scopus 로고
    • Serum hyaluronate levels as predictor of radiologic progression in early rheumatoid arthritis
    • Paimela, L., Heiskanen, A., Kurki, P., Helve, T. & Leirisalo-Repo, M.: Serum hyaluronate levels as predictor of radiologic progression in early rheumatoid arthritis. Arthritis Rheum. 34: 815-821, 1991.
    • (1991) Arthritis Rheum. , vol.34 , pp. 815-821
    • Paimela, L.1    Heiskanen, A.2    Kurki, P.3    Helve, T.4    Leirisalo-Repo, M.5
  • 56
    • 0026735595 scopus 로고
    • Antikeratin antibodies: Diagnostic and prognostic markers for early rheumatoid arthritis
    • Paimela, L., Gripenberg, M., Kurki, P. & Leirisalo-Repo, M.: Antikeratin antibodies: diagnostic and prognostic markers for early rheumatoid arthritis. Ann. Rheum. Dis. 41: 743-746, 1992.
    • (1992) Ann. Rheum. Dis. , vol.41 , pp. 743-746
    • Paimela, L.1    Gripenberg, M.2    Kurki, P.3    Leirisalo-Repo, M.4
  • 57
  • 58
    • 0028564689 scopus 로고
    • Type I collagen degradation products in serum of patients with early rheumatoid arthritis: Relationship to disease activity and radiological progression in a 3-year follow-up
    • Paimela, L., Leirisalo-Repo, M., Risteli, L., Hakala, M., Helve, T. & Risteli, J.: Type I collagen degradation products in serum of patients with early rheumatoid arthritis: Relationship to disease activity and radiological progression in a 3-year follow-up. Br. J. Rheumatol. 33: 1012-1016, 1994.
    • (1994) Br. J. Rheumatol. , vol.33 , pp. 1012-1016
    • Paimela, L.1    Leirisalo-Repo, M.2    Risteli, L.3    Hakala, M.4    Helve, T.5    Risteli, J.6
  • 59
    • 2142719914 scopus 로고
    • Acute phase proteins, C-reactive protein and serum amyloid A protein
    • Pepys, M. B.: Acute phase proteins, C-reactive protein and serum amyloid A protein. Rheumatology in Europe 24: 26-28, 1995.
    • (1995) Rheumatology in Europe , vol.24 , pp. 26-28
    • Pepys, M.B.1
  • 60
    • 0026780956 scopus 로고
    • Rheumatology function tests: Grip strength, walking time, button test and questionnaires document and predict longterm morbidity and mortality in rheumatoid arthritis
    • Pincus, T. & Callahan, L. F.: Rheumatology function tests: grip strength, walking time, button test and questionnaires document and predict longterm morbidity and mortality in rheumatoid arthritis. J. Rheumatol. 19: 1051-1057, 1992.
    • (1992) J. Rheumatol. , vol.19 , pp. 1051-1057
    • Pincus, T.1    Callahan, L.F.2
  • 62
    • 0028322114 scopus 로고
    • Biological markers in rheumatoid arthritis
    • Poole, A. R. & Dieppe, P.: Biological markers in rheumatoid arthritis. Semin. Arthritis Rheum. 23 (Suppl. 2): 17-31, 1994.
    • (1994) Semin. Arthritis Rheum. , vol.23 , Issue.2 SUPPL. , pp. 17-31
    • Poole, A.R.1    Dieppe, P.2
  • 63
    • 0025285567 scopus 로고
    • Inflammation and cartilage metabolism in rheumatoid arthritis: Studies of the blood markers hyaluronic acid, orosomucoid and keratan sulfate
    • Poole, A. R., Witter, J., Roberts, N., Piccolo, F., Brandt, R., Paquin, J. & Baron, M.: Inflammation and cartilage metabolism in rheumatoid arthritis: studies of the blood markers hyaluronic acid, orosomucoid and keratan sulfate. Arthritis Rheum. 33: 790-799, 1990.
    • (1990) Arthritis Rheum. , vol.33 , pp. 790-799
    • Poole, A.R.1    Witter, J.2    Roberts, N.3    Piccolo, F.4    Brandt, R.5    Paquin, J.6    Baron, M.7
  • 64
    • 0027474177 scopus 로고
    • The quantitation of a native chondroitin sulfate epitope in synovial fluid lavages and articular cartilage from canine experimental osteoarthritis and disuse atrophy
    • Ratcliffe, A., Shurety, W. & Caterson, B.: The quantitation of a native chondroitin sulfate epitope in synovial fluid lavages and articular cartilage from canine experimental osteoarthritis and disuse atrophy. Arthritis Rheum. 36: 543-551, 1993.
    • (1993) Arthritis Rheum. , vol.36 , pp. 543-551
    • Ratcliffe, A.1    Shurety, W.2    Caterson, B.3
  • 65
    • 0027417926 scopus 로고
    • Radioimmunoassay for the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen: A new serum marker of bone collagen degradation
    • Risteli, J., Elomaa, I., Niemi, S., Novamo, A. & Risteli, L.: Radioimmunoassay for the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen: A new serum marker of bone collagen degradation. Clin. Chem. 39: 635-640, 1993.
    • (1993) Clin. Chem. , vol.39 , pp. 635-640
    • Risteli, J.1    Elomaa, I.2    Niemi, S.3    Novamo, A.4    Risteli, L.5
  • 67
    • 0027064478 scopus 로고
    • Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease
    • Rizkalla, G., Reiner, A., Bogoch, E. & Poole, A. R.: Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease. J. Clin. Invest. 90: 2268-2277, 1992.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2268-2277
    • Rizkalla, G.1    Reiner, A.2    Bogoch, E.3    Poole, A.R.4
  • 68
    • 0027216718 scopus 로고
    • The association of HLA DRB alleles with self- and persistent forms of early symmetrical polyarthritis
    • Salmon, M., Wordsworth, P., Emery, P., Tunn, E., Bacon, P. A. & Bell, J. I.: The association of HLA DRB alleles with self- and persistent forms of early symmetrical polyarthritis. Br. J. Rheumatol. 32: 628-630, 1993.
    • (1993) Br. J. Rheumatol. , vol.32 , pp. 628-630
    • Salmon, M.1    Wordsworth, P.2    Emery, P.3    Tunn, E.4    Bacon, P.A.5    Bell, J.I.6
  • 69
    • 0024449973 scopus 로고
    • Involvement of nonarticular cartilage, as demonstrated by release of a cartilage-specific protein, in rheumatoid arthritis
    • Saxne, T. & Heinegård, D.: Involvement of nonarticular cartilage, as demonstrated by release of a cartilage-specific protein, in rheumatoid arthritis. Arthritis Rheum. 32: 1080-1086, 1989.
    • (1989) Arthritis Rheum. , vol.32 , pp. 1080-1086
    • Saxne, T.1    Heinegård, D.2
  • 70
    • 0026710173 scopus 로고
    • Synovial fluid analyses of two groups of proteoglycan epitopes distinguishes early and late cartilage lesions
    • Saxne, T. & Heinegård, D.: Synovial fluid analyses of two groups of proteoglycan epitopes distinguishes early and late cartilage lesions. Arthritis. Rheum. 35: 385-390, 1992a.
    • (1992) Arthritis. Rheum. , vol.35 , pp. 385-390
    • Saxne, T.1    Heinegård, D.2
  • 71
    • 0026660250 scopus 로고
    • Cartilage oligomeric matrix protein. A novel marker of cartilage detectable in synovial fluid and blood
    • Saxne, T. & Heinegård, D.: Cartilage oligomeric matrix protein. A novel marker of cartilage detectable in synovial fluid and blood. Br. J. Rheumatol. 31: 583-591, 1992b.
    • (1992) Br. J. Rheumatol. , vol.31 , pp. 583-591
    • Saxne, T.1    Heinegård, D.2
  • 72
    • 0028798267 scopus 로고
    • Serum concentrations of two cartilage matrix proteins reflecting different aspects of cartilage turnover in relapsing polychondritis
    • Saxne, T. & Heinegård, D.: Serum concentrations of two cartilage matrix proteins reflecting different aspects of cartilage turnover in relapsing polychondritis. Arthritis Rheum. 38: 294-296, 1995a.
    • (1995) Arthritis Rheum. , vol.38 , pp. 294-296
    • Saxne, T.1    Heinegård, D.2
  • 73
    • 0028917932 scopus 로고
    • Matrix proteins: Potentials as body fluid markers of changes in the metabolism of cartilage and bone in arthritis
    • Saxne, T. & Heinegård, D.: Matrix proteins: Potentials as body fluid markers of changes in the metabolism of cartilage and bone in arthritis. J. Rheumatol. (Suppl. 43) 22: 71-74, 1995b.
    • (1995) J. Rheumatol. (Suppl. 43) , vol.22 , pp. 71-74
    • Saxne, T.1    Heinegård, D.2
  • 74
    • 0021889712 scopus 로고
    • Differences in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis
    • Saxne, T., Heinegård, D., Wollheim, F. A. & Pettersson, H.: Differences in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis. Lancet 8447: 127-128, 1985.
    • (1985) Lancet , vol.8447 , pp. 127-128
    • Saxne, T.1    Heinegård, D.2    Wollheim, F.A.3    Pettersson, H.4
  • 75
    • 0023627069 scopus 로고
    • Proteoglycan concentration in synovial fluid: Predictor of future cartilage destruction in rheumatoid arthritis?
    • Saxne, T., Wollheim, F. A., Pettersson, H., Heinegård, D.: Proteoglycan concentration in synovial fluid: predictor of future cartilage destruction in rheumatoid arthritis? Brit. Med. J. 295: 1447-1448, 1987.
    • (1987) Brit. Med. J. , vol.295 , pp. 1447-1448
    • Saxne, T.1    Wollheim, F.A.2    Pettersson, H.3    Heinegård, D.4
  • 76
    • 0027450967 scopus 로고
    • Release of cartilage macromolecules into synovial fluid in acute and prolonged stages of reactive arthritis
    • Saxne, T., Glennås, A., Kvien, T. K., Mellby, K. & Heinegård, D.: Release of cartilage macromolecules into synovial fluid in acute and prolonged stages of reactive arthritis. Arthritis Rheum. 36: 20-25, 1993.
    • (1993) Arthritis Rheum. , vol.36 , pp. 20-25
    • Saxne, T.1    Glennås, A.2    Kvien, T.K.3    Mellby, K.4    Heinegård, D.5
  • 77
    • 9244250762 scopus 로고
    • Aggrecan markers in synovial fluid in rheumatoid arthritis and reactive arthritis
    • Saxne, T., Månsson, B., Ionescu, M., Poole, A. R. & Heinegård, D.: Aggrecan markers in synovial fluid in rheumatoid arthritis and reactive arthritis. Arthritis Rheum. 37: S344, 1994.
    • (1994) Arthritis Rheum. , vol.37
    • Saxne, T.1    Månsson, B.2    Ionescu, M.3    Poole, A.R.4    Heinegård, D.5
  • 78
    • 0028797761 scopus 로고
    • Increased release of bone sialoprotein into synovial fluid reflects tissue destruction in rheumatoid arthritis
    • Saxne, T., Zunino, L. & Heinegård, D.: Increased release of bone sialoprotein into synovial fluid reflects tissue destruction in rheumatoid arthritis. Arthritis Rheum. 38: 82-90, 1995a.
    • (1995) Arthritis Rheum. , vol.38 , pp. 82-90
    • Saxne, T.1    Zunino, L.2    Heinegård, D.3
  • 80
    • 0029017016 scopus 로고
    • The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies
    • Sebbag, M., Simon, M., Vincent, C., Masson-Bessière, C., Girbal, E., Durieux, J.-J. & Serre, G.: The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies. J. Clin. Invest. 95: 2672-2679, 1995.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2672-2679
    • Sebbag, M.1    Simon, M.2    Vincent, C.3    Masson-Bessière, C.4    Girbal, E.5    Durieux, J.-J.6    Serre, G.7
  • 81
    • 0024460791 scopus 로고
    • Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic disease
    • Seibel, M. J., Duncan, A. & Robins, S. P.: Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic disease. J. Rheumatol. 16: 964-970, 1989.
    • (1989) J. Rheumatol. , vol.16 , pp. 964-970
    • Seibel, M.J.1    Duncan, A.2    Robins, S.P.3
  • 83
    • 0028899665 scopus 로고
    • Significance of the levels of carboxy terminal type II procollagen peptide, chondroitin sulfate isomers, tissue inhibitor of metalloproteinases, and metalloproteinases in osteoarthritis joint fluid
    • Shinmei, M., Kobayashi, T., Yoshihara, Y. & Samara, A.: Significance of the levels of carboxy terminal type II procollagen peptide, chondroitin sulfate isomers, tissue inhibitor of metalloproteinases, and metalloproteinases in osteoarthritis joint fluid. J. Rheumatol. 22: (Suppl. 43) 78-81, 1995.
    • (1995) J. Rheumatol. , vol.22 , Issue.43 SUPPL. , pp. 78-81
    • Shinmei, M.1    Kobayashi, T.2    Yoshihara, Y.3    Samara, A.4
  • 84
    • 0028558328 scopus 로고
    • Epidemiology of rheumatoid arthritis
    • Silman, A. J., Epidemiology of rheumatoid arthritis. APMIS 102: 721-728, 1994.
    • (1994) APMIS , vol.102 , pp. 721-728
    • Silman, A.J.1
  • 85
    • 0029094866 scopus 로고
    • Synovial perfusion in the human knee: A methodologic analysis
    • Simkin, P. A., Bassett, J. E. & Koh, E.-M.: Synovial perfusion in the human knee: A methodologic analysis. Semin. Arthritis Rheum. 25: 56-66, 1995.
    • (1995) Semin. Arthritis Rheum. , vol.25 , pp. 56-66
    • Simkin, P.A.1    Bassett, J.E.2    Koh, E.-M.3
  • 86
  • 88
    • 0029099108 scopus 로고
    • Interleukin-1 receptor antagonist in patients with active systemic lupus erythematosus. Enhanced production by monocytes and correlation with disease activity
    • Suzuki, H., Takemura, H. & Kashiwagi, H.: Interleukin-1 receptor antagonist in patients with active systemic lupus erythematosus. Enhanced production by monocytes and correlation with disease activity. Arthritis Rheum. 38: 1055-1059, 1995.
    • (1995) Arthritis Rheum. , vol.38 , pp. 1055-1059
    • Suzuki, H.1    Takemura, H.2    Kashiwagi, H.3
  • 89
    • 9244241948 scopus 로고
    • Serum cytidine deaminase as an integrated measure of acute inflammation
    • Thompson, P. W., Jones, D. D. & Currey, H. L. F.: Serum cytidine deaminase as an integrated measure of acute inflammation. Br. J. Rheumatol. 25: 97-98, 1986.
    • (1986) Br. J. Rheumatol. , vol.25 , pp. 97-98
    • Thompson, P.W.1    Jones, D.D.2    Currey, H.L.F.3
  • 91
    • 0026630114 scopus 로고
    • Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis. A prospective follow-up study of 147 patients
    • van der Heijde, D. M., van Riel, P. L., van Leeuwen, M. A., van't Hof, M. A., van Rijswijk, M. H. & van De Putte, L. B.: Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis. A prospective follow-up study of 147 patients. Br. J. Rheumatol. 31: 519-525, 1992.
    • (1992) Br. J. Rheumatol. , vol.31 , pp. 519-525
    • Van Der Heijde, D.M.1    Van Riel, P.L.2    Van Leeuwen, M.A.3    Van't Hof, M.A.4    Van Rijswijk, M.H.5    Van De Putte, L.B.6
  • 93
    • 0028888406 scopus 로고
    • Interleukin-6 in relation to other proinflammatory cytokines, chemotactic activity and neutrophil activation in rheumatoid synovial fluid
    • van Leeuwen, M. A., Westra, J., Limburg, P. C., van Riel, P. L. C. M. & van Rijswijk, M. H.: Interleukin-6 in relation to other proinflammatory cytokines, chemotactic activity and neutrophil activation in rheumatoid synovial fluid. Ann. Rheum. Dis. 54: 33-38, 1995a.
    • (1995) Ann. Rheum. Dis. , vol.54 , pp. 33-38
    • Van Leeuwen, M.A.1    Westra, J.2    Limburg, P.C.3    Van Riel, P.L.C.M.4    Van Rijswijk, M.H.5
  • 94
    • 0028989657 scopus 로고
    • IgM, IgA, and IgG rheumatoid factors in early rheumatoid arthritis predictive of radiological progression?
    • van Leeuwen, M. A., Westra, J., van Riel, P. L., Limburg, P. C. & van Rijswijk, M. H.: IgM, IgA, and IgG rheumatoid factors in early rheumatoid arthritis predictive of radiological progression? Scand. J. Rheumatol. 24: 146-153, 1995b.
    • (1995) Scand. J. Rheumatol. , vol.24 , pp. 146-153
    • Van Leeuwen, M.A.1    Westra, J.2    Van Riel, P.L.3    Limburg, P.C.4    Van Rijswijk, M.H.5
  • 95
    • 9244220527 scopus 로고
    • Acute phase reactants and radiological damage in rheumatoid arthritis
    • van Rijswijk, M.: Acute phase reactants and radiological damage in rheumatoid arthritis. Rheumatology in Europe (Suppl. 2) 24: 171-172, 1995.
    • (1995) Rheumatology in Europe (Suppl. 2) , vol.24 , pp. 171-172
    • Van Rijswijk, M.1
  • 96
    • 0025764433 scopus 로고
    • Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a followup study
    • van Zeben, D., Hazes, J., Zwinderman, A., Cats, A., Schreuder, G., D'Amaro, J. & Breedveld, F.: Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a followup study. Arthritis Rheum. 34: 822-830, 1991.
    • (1991) Arthritis Rheum. , vol.34 , pp. 822-830
    • Van Zeben, D.1    Hazes, J.2    Zwinderman, A.3    Cats, A.4    Schreuder, G.5    D'Amaro, J.6    Breedveld, F.7
  • 97
    • 0028946260 scopus 로고
    • Increased proteoglycan synthesis in cartilage in experimental canine osteoarthritis does not reflect a permanent change in chondrocyte phenotype
    • Venn, G., Billingham, M. E. J. & Hardingham, T. E.: Increased proteoglycan synthesis in cartilage in experimental canine osteoarthritis does not reflect a permanent change in chondrocyte phenotype. Arthritis Rheum. 38: 525-532, 1995.
    • (1995) Arthritis Rheum. , vol.38 , pp. 525-532
    • Venn, G.1    Billingham, M.E.J.2    Hardingham, T.E.3
  • 98
    • 0026447387 scopus 로고
    • The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis
    • Weyand, C., Hicok, K., Conn, D. & Gronzy, J.: The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann. Int. Med. 117: 801-806, 1992.
    • (1992) Ann. Int. Med. , vol.117 , pp. 801-806
    • Weyand, C.1    Hicok, K.2    Conn, D.3    Gronzy, J.4
  • 99
    • 0028907841 scopus 로고
    • Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis
    • Weyand, C. M., McCarthy, T. G. & Goronzy, J. J.: Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis. J. Clin. Invest. 95: 2120-2126, 1995.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2120-2126
    • Weyand, C.M.1    McCarthy, T.G.2    Goronzy, J.J.3
  • 100
    • 0026729494 scopus 로고
    • The search for laboratory measures of outcome in rheumatoid arthritis
    • Scott, D. L. (Ed.)
    • Wollheim, F. A. & Eberhardt, K. B.: The search for laboratory measures of outcome in rheumatoid arthritis. In: Scott, D. L. (Ed.): Baillieres Clinical Rheumatology 6 No. 1, 1992, pp. 69-93.
    • (1992) Baillieres Clinical Rheumatology , vol.6 , Issue.1 , pp. 69-93
    • Wollheim, F.A.1    Eberhardt, K.B.2
  • 101
    • 9244240192 scopus 로고
    • Markers of cartilage destruction
    • Smolen, J. S., Kalden, J. R. & Maini, R. N. (Eds): Springer-Verlag, Berlin Heidelberg
    • Wollheim, F. A. & Saxne, T.: Markers of cartilage destruction. In: Smolen, J. S., Kalden, J. R. & Maini, R. N. (Eds): Rheumatoid Arthritis. Recent Research Advances. Springer-Verlag, Berlin Heidelberg 1992, pp. 248-262.
    • (1992) Rheumatoid Arthritis. Recent Research Advances , pp. 248-262
    • Wollheim, F.A.1    Saxne, T.2
  • 102
    • 0024829522 scopus 로고
    • HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region
    • Wordsworth, B. P., Lanchbury, J. S., Sakkas, L. I., Welsh, K. I., Panayi, G. S. & Bell, J. I.: HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region. Proc. Natl. Acad. Sci. USA 86: 10049-10053, 1989.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 10049-10053
    • Wordsworth, B.P.1    Lanchbury, J.S.2    Sakkas, L.I.3    Welsh, K.I.4    Panayi, G.S.5    Bell, J.I.6
  • 103
    • 0025869837 scopus 로고
    • Limited heterogeneity of the HLA class II contribution to susceptibility to rheumatoid arthritis is suggested by positive associations with HLA-DR4, DR1 and Drw10
    • Wordsworth, B. P., Stedeford, J., Rosenberg, W. M. C. & Bell, J. I.: Limited heterogeneity of the HLA class II contribution to susceptibility to rheumatoid arthritis is suggested by positive associations with HLA-DR4, DR1 and Drw10. Br. J. Rheumatol. 30: 178-180, 1991.
    • (1991) Br. J. Rheumatol. , vol.30 , pp. 178-180
    • Wordsworth, B.P.1    Stedeford, J.2    Rosenberg, W.M.C.3    Bell, J.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.