Characterization of the effects of tebufelone on hepatic cytochromes P450 in the beagle dog

Drug Metabolism and Disposition

Volumn 24, Issue 5, 1996, Pages 523-528

  Smith, Bill J ^a   Zupan, Lori A ^a   Hu, Joanna K ^a   Diters, Richard W ^b   Gibson, George W ^b   Norton, John N ^a,c  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^b Woods Corners Laboratories

^c ALCON RESEARCH LTD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; ETHOXYRESORUFIN DEETHYLASE; PHENOBARBITAL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TEBUFELONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; DOG; DOSE RESPONSE; DRUG METABOLISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; LIVER CELL; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; SMOOTH ENDOPLASMIC RETICULUM; TISSUE DISTRIBUTION;

ALKYNES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARYL HYDROCARBON HYDROXYLASES; CHLORAMPHENICOL; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; ENZYME INDUCTION; FEMALE; IMMUNOBLOTTING; LIVER; MALE; MICROSCOPY, ELECTRON; MICROSOMES, LIVER; NADH DEHYDROGENASE; OXIDOREDUCTASES, N-DEMETHYLATING; OXIDOREDUCTASES, O-DEMETHYLATING; PHENOLS; STEROID HYDROXYLASES; TROLEANDOMYCIN;

ANIMALIA; CANIS FAMILIARIS;

EID: 0029920832     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

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