메뉴 건너뛰기




Volumn 10, Issue 1, 1996, Pages 177-187

Endocrine disorders associated with mutations in guanine nucleotide binding proteins

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN;

EID: 0029920610     PISSN: 0950351X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0950-351X(96)80378-8     Document Type: Article
Times cited : (6)

References (60)
  • 1
    • 0027202237 scopus 로고
    • Clinical and biochemical characteristics of acromegalic patients harboring gsp-positive and gsp-negative pituitary tumors
    • Adams EF Brockmeier S Friedman E Clinical and biochemical characteristics of acromegalic patients harboring gsp -positive and gsp -negative pituitary tumors Neurosurgery 33 1993 198 203
    • (1993) Neurosurgery , vol.33 , pp. 198-203
    • Adams, EF1    Brockmeier, S2    Friedman, E3
  • 2
    • 0027340385 scopus 로고
    • Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by α2-adrenergic receptors expressed in fibroblasts
    • 2-adrenergic receptors expressed in fibroblasts Journal of Biological Chemistry 268 1993 22235 22238
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 22235-22238
    • Alblas, J1    van Corven, EJ2    Hordijk, PL3
  • 4
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: a review
    • Bos JL Ras oncogenes in human cancer: a review Cancer Research 49 1989 4682 4689
    • (1989) Cancer Research , vol.49 , pp. 4682-4689
    • Bos, JL1
  • 5
    • 0025010979 scopus 로고
    • The GTPase superfamily: A conserved switch for diverse cell functions
    • Bourne HR Sanders DA McCormick F The GTPase superfamily: A conserved switch for diverse cell functions Nature (London) 348 1990 125 132
    • (1990) Nature (London) , vol.348 , pp. 125-132
    • Bourne, HR1    Sanders, DA2    McCormick, F3
  • 6
    • 0028917954 scopus 로고
    • Regulation of ras-mediated signalling: more than one way to skin a cat
    • Burgering BMT Bos JL Regulation of ras -mediated signalling: more than one way to skin a cat Trends in Biochemical Sciences 20 1995 18 22
    • (1995) Trends in Biochemical Sciences , vol.20 , pp. 18-22
    • Burgering, BMT1    Bos, JL2
  • 7
    • 0026062347 scopus 로고
    • Pituitary hyperplasia and gigantism in mice caused by a cholera toxin transgene
    • Burton FH Hasel KW Bloom FE Sutcliffe JG Pituitary hyperplasia and gigantism in mice caused by a cholera toxin transgene Nature (London) 350 1991 74 77
    • (1991) Nature (London) , vol.350 , pp. 74-77
    • Burton, FH1    Hasel, KW2    Bloom, FE3    Sutcliffe, JG4
  • 8
    • 0023425955 scopus 로고
    • Reduced expression of multiple forms of the α subunit of the stimulatory GTP-binding protein pseudohypothyroidism type la
    • Carter A Bardin C Collins R Reduced expression of multiple forms of the α subunit of the stimulatory GTP-binding protein pseudohypothyroidism type la Proceedings of the National Academy of Sciences of the USA 84 1987 7266 7269
    • (1987) , pp. 7266-7269
    • Carter, A1    Bardin, C2    Collins, R3
  • 9
    • 0025285138 scopus 로고
    • A new constitutively activating mutation of the Gs protein α subunit-gsp oncogene is found in human pituitary tumours
    • s protein α subunit- gsp oncogene is found in human pituitary tumours Oncogene 5 1990 1059 1061
    • (1990) Oncogene , vol.5 , pp. 1059-1061
    • Clementi, E1    Malgaretti, N2    Meldolesi, J3    Taramelli, R4
  • 10
    • 0028240869 scopus 로고
    • Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits
    • Crespo P Xu N Simonds WF Gutkind JS Ras -dependent activation of MAP kinase pathway mediated by G-protein βγ subunits Nature (London) 369 1994 418 420
    • (1994) Nature (London) , vol.369 , pp. 418-420
    • Crespo, P1    Xu, N2    Simonds, WF3    Gutkind, JS4
  • 12
    • 0026698944 scopus 로고
    • Identification of G protein α subunit mutations in human growth hormone (GH) and GH/prolactin-secreting pituitary tumours by single-strand conformation polymorphism
    • Drews RT Gravel RA Collu R Identification of G protein α subunit mutations in human growth hormone (GH) and GH/prolactin-secreting pituitary tumours by single-strand conformation polymorphism Molecular and Cellular Endocrinology 87 1992 125 129
    • (1992) Molecular and Cellular Endocrinology , vol.87 , pp. 125-129
    • Drews, RT1    Gravel, RA2    Collu, R3
  • 13
  • 14
    • 0028176297 scopus 로고
    • cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
    • Faure M Voyno-Yasenetskaya TA Boume HR cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells Journal of Biological Chemistry 269 1994 7851 7854
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 7851-7854
    • Faure, M1    Voyno-Yasenetskaya, TA2    Boume, HR3
  • 15
    • 0024854388 scopus 로고
    • Mutations of Gsα designed to alter the reactivity of the protein with bacterial toxins
    • sα designed to alter the reactivity of the protein with bacterial toxins Substitutions at Arg187 result in a loss of GTPase activity Journal of Biological Chemistry 264 1989 21907 21964
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 21907-21964
    • Freissmuth, M1    Gilman, AG2
  • 16
    • 0022654257 scopus 로고
    • The McCune—Albright syndrome: A lethal gene surviving by mosaicism
    • Happle R The McCune—Albright syndrome: A lethal gene surviving by mosaicism Clinical Genetics 29 1986 321 324
    • (1986) Clinical Genetics , vol.29 , pp. 321-324
    • Happle, R1
  • 18
    • 0027956207 scopus 로고
    • Rapid GDP release from Gsα in patients with gain and loss of endocrine function
    • sα in patients with gain and loss of endocrine function Nature (London) 371 1994 164 168
    • (1994) Nature (London) , vol.371 , pp. 164-168
    • Iiri, T1    Herzmark, P2    Nakamoto, JM3
  • 19
    • 0027303269 scopus 로고
    • The transforming activity of activated Gα12
    • Jiang H Wu D Simon MI The transforming activity of activated Gα12 FEBS Letters 330 1993 319 322
    • (1993) FEBS Letters , vol.330 , pp. 319-322
    • Jiang, H1    Wu, D2    Simon, MI3
  • 21
    • 0025910365 scopus 로고
    • Structure and function of signal-transducing GTP-binding proteins
    • Kaziro Y Itoh H Kozasa T Structure and function of signal-transducing GTP-binding proteins Annual Review of Biochemistry 60 1991 349 400
    • (1991) , pp. 349-400
    • Kaziro, Y1    Itoh, H2    Kozasa, T3
  • 22
    • 0025612353 scopus 로고
    • Editorial: Further evidence for a somatic mutation theory in the pathogenesis of human pituitary tumors
    • Klibanski A Editorial: Further evidence for a somatic mutation theory in the pathogenesis of human pituitary tumors Journal of Clinical Endocrinology and Metabolism 71 1990 1415A 1415C
    • (1990) Journal of Clinical Endocrinology and Metabolism , vol.71 , pp. 1415A-1415C
    • Klibanski, A1
  • 23
    • 0028670476 scopus 로고
    • Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by Gβγ activation of p21ras
    • ras Proceedings of the National Academy of Sciences of the USA 91 1994 12706 12710
    • (1994) , pp. 12706-12710
    • Koch, WJ1    Hawes, BE2    Allen, LF3    Lefkowitz, RJ4
  • 24
    • 0024404145 scopus 로고
    • GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours
    • s and stimulate adenylyl cyclase in human pituitary tumours Nature (London) 340 1989 692 696
    • (1989) Nature (London) , vol.340 , pp. 692-696
    • Landis, CA1    Masters, SB2    Spada, A3
  • 25
    • 0025606557 scopus 로고
    • Clinical characteristics of acromegalic patients whose pituitary tumors contain mutant G, protein
    • Landis CA Harsh G Lyons J Clinical characteristics of acromegalic patients whose pituitary tumors contain mutant G, protein Journal of Clinical Endocrinology and Metabolism 71 1990 1416 1420
    • (1990) Journal of Clinical Endocrinology and Metabolism , vol.71 , pp. 1416-1420
    • Landis, CA1    Harsh, G2    Lyons, J3
  • 26
    • 0022655674 scopus 로고
    • Activity of the stimulatory guanine nucleotide binding protein is reduced in erthyrocytes from patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism: Biochemical, endocrine, and genetic analysis of Albright's hereditary osteodystrophy in six kindreds
    • Levine MA Jap TS Mauseth RS Activity of the stimulatory guanine nucleotide binding protein is reduced in erthyrocytes from patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism: Biochemical, endocrine, and genetic analysis of Albright's hereditary osteodystrophy in six kindreds Journal of Clinical Endocrinology and Metabolism 62 1986 497 502
    • (1986) Journal of Clinical Endocrinology and Metabolism , vol.62 , pp. 497-502
    • Levine, MA1    Jap, TS2    Mauseth, RS3
  • 27
    • 0007406646 scopus 로고
    • Genetic deficiency of the α subunit of the guanine nucleotide-binding protein Gs as the molecular basis for Albright hereditary osteodystrophy
    • s as the molecular basis for Albright hereditary osteodystrophy Proceedings of the National Academy of Sciences of the USA 85 1988 617 621
    • (1988) , pp. 617-621
    • Levine, MA1    Ahn, TG2    Klupt, SF3
  • 29
    • 0025127424 scopus 로고
    • Two G-protein oncogenes in human endocrine tumors
    • Lyons J Landis CA Harsh G Two G-protein oncogenes in human endocrine tumors Science 249 1990 655 659
    • (1990) Science , vol.249 , pp. 655-659
    • Lyons, J1    Landis, CA2    Harsh, G3
  • 30
    • 0025239605 scopus 로고
    • δ-Opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2
    • i2 Biochemical Journal 267 1990 391 398
    • (1990) Biochemical Journal , vol.267 , pp. 391-398
    • McKenzie, FR1    Milligan, G2
  • 31
    • 0004116691 scopus 로고
    • Mutations within the gene encoding the stimulatory G-protein of adenylyl cyclase as the basis for Albright hereditary osteodystrophy
    • Miric A Levine MA Mutations within the gene encoding the stimulatory G-protein of adenylyl cyclase as the basis for Albright hereditary osteodystrophy Milligan G Wakelam M G-Proteins: Signal Transduction and Disease 1992 Academic Press London, UK 29 46
    • (1992) , pp. 29-46
    • Miric, A1    Levine, MA2
  • 32
    • 0027210606 scopus 로고
    • Heterogenous mutations in the gene encoding the a subunit of the stimulatory G-protein of adenylyl cyclase in Albright hereditary osteodystrophy
    • Miric A Vechio JD Levine MA Heterogenous mutations in the gene encoding the a subunit of the stimulatory G-protein of adenylyl cyclase in Albright hereditary osteodystrophy Journal of Clinical Endocrinology and Metabolism 76 1993 1560 1568
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , pp. 1560-1568
    • Miric, A1    Vechio, JD2    Levine, MA3
  • 33
    • 4243867133 scopus 로고
    • A missense mutation in the Gsα gene is associated with pseudohypoparathyroidism type 1-A and gonadotropin-independent precocious puberty
    • sα gene is associated with pseudohypoparathyroidism type 1-A and gonadotropin-independent precocious puberty Clinical Research 41 1993 40A
    • (1993) Clinical Research , vol.41 , pp. 40A
    • Nakomoto, JM1    Jones, EA2    Zimmerman, D3
  • 34
    • 0026009016 scopus 로고
    • Activating point mutations of the gsp oncogene in human thyroid adenomas
    • O'Sullivan C Barton CM Staddon SL Activating point mutations of the gsp oncogene in human thyroid adenomas Molecular Carcinogenesis 4 1991 345 349
    • (1991) Molecular Carcinogenesis , vol.4 , pp. 345-349
    • O'Sullivan, C1    Barton, CM2    Staddon, SL3
  • 35
    • 0025173391 scopus 로고
    • Immunochemical analysis of the α subunit of the stimulatory G-protein of adenylyl cyclase in patients with Albright's hereditary osteodystrophy
    • Patten JL Levine MA Immunochemical analysis of the α subunit of the stimulatory G-protein of adenylyl cyclase in patients with Albright's hereditary osteodystrophy Journal of Clinical Endocrinology and Metabolism 71 1990 1208 2114
    • (1990) Journal of Clinical Endocrinology and Metabolism , vol.71 , pp. 1208-2114
    • Patten, JL1    Levine, MA2
  • 36
    • 0025323257 scopus 로고
    • Mutation in the gene encoding the stimulatory G-protein of adenylate cyclase in Albright's hereditary osteodystrophy
    • Patten JL Johns DR Valle D Mutation in the gene encoding the stimulatory G-protein of adenylate cyclase in Albright's hereditary osteodystrophy New England Journal of Medicine 322 1990 1412 1419
    • (1990) New England Journal of Medicine , vol.322 , pp. 1412-1419
    • Patten, JL1    Johns, DR2    Valle, D3
  • 38
    • 0026694168 scopus 로고
    • Identification of a mutation in the gene encoding the a subunit of the stimulatory G-protein of adenylyl cyclase in McCune—Albright syndrome
    • Schwindinger WF Francomano CA Levine MA Identification of a mutation in the gene encoding the a subunit of the stimulatory G-protein of adenylyl cyclase in McCune—Albright syndrome Proceedings of the National Academy of Sciences of the USA 89 1992 5152 5156
    • (1992) , pp. 5152-5156
    • Schwindinger, WF1    Francomano, CA2    Levine, MA3
  • 39
    • 0028172104 scopus 로고
    • A novel Gsα mutant in a patient with Albright hereditary osteodystrophy uncouples cell surface receptors from adenylyl cyclase
    • sα mutant in a patient with Albright hereditary osteodystrophy uncouples cell surface receptors from adenylyl cyclase Journal of Biological Chemistry 269 1994 25387 25391
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 25387-25391
    • Schwindinger, WF1    Miric, A2    Zimmerman, D3    Levine, MA4
  • 40
    • 0027400489 scopus 로고
    • Stimulation of human thyroid growth via the inhibitory guanine nucleotide binding (G) protein Gi: Constitutive expression of the G-protein a subunit α Giα-1 in autonomous adenoma
    • iα-1 in autonomous adenoma Proceedings of the National Academy of Sciences of the USA 90 1993 1609 1613
    • (1993) , pp. 1609-1613
    • Selzer, E1    Wilfing, A2    Schiferer, A3
  • 41
    • 0026528602 scopus 로고
    • G-protein-controlled signal transduction pathways and the regulation of cell proliferation
    • Seuwen K Pouyssegur J G-protein-controlled signal transduction pathways and the regulation of cell proliferation Advances in Cancer Research 58 1992 75 94
    • (1992) Advances in Cancer Research , vol.58 , pp. 75-94
    • Seuwen, K1    Pouyssegur, J2
  • 42
    • 0027485031 scopus 로고
    • Increasing cAMP attenuates activation of mitogenactivated protein kinase
    • Sevetson BR Kong X Lawrence JC Jr Increasing cAMP attenuates activation of mitogenactivated protein kinase Proceedings of the National Academy of Sciences of the USA 90 1993 10305 10309
    • (1993) , pp. 10305-10309
    • Sevetson, BR1    Kong, X2    Lawrence, JC3
  • 43
    • 0022656444 scopus 로고
    • Selective resistance to parathyroid hormone in cultured skin fibroblasts from patients with pseudohypoparathyroidism type lb
    • Silve C Santora A Breslau N Selective resistance to parathyroid hormone in cultured skin fibroblasts from patients with pseudohypoparathyroidism type lb Journal of Clinical Endocrinology and Metabolism 62 1986 640 644
    • (1986) Journal of Clinical Endocrinology and Metabolism , vol.62 , pp. 640-644
    • Silve, C1    Santora, A2    Breslau, N3
  • 44
    • 0024746268 scopus 로고
    • G12 mediates α2-adrenergic inhibition of adenylyl cyclase in platelet membranes
    • 2-adrenergic inhibition of adenylyl cyclase in platelet membranes In situ identification with Ga C-terminal antibodies Proceedings of the National Academy Sciences of the USA 86 1989 7809 7813
    • (1989) , pp. 7809-7813
    • Simonds, WF1    Goldsmith, PK2    Codina, J3
  • 45
    • 0027372340 scopus 로고
    • A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
    • Skenker A Laue L Kosugi S A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty Nature (London) 365 1993 652 654
    • (1993) Nature (London) , vol.365 , pp. 652-654
    • Skenker, A1    Laue, L2    Kosugi, S3
  • 46
    • 0025695763 scopus 로고
    • Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase
    • Spada A Arosio M Bochicçhio D Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase Journal of Clinical Endocrinology and Metabolism 71 1990 1421 1426
    • (1990) Journal of Clinical Endocrinology and Metabolism , vol.71 , pp. 1421-1426
    • Spada, A1    Arosio, M2    Bochicçhio, D3
  • 47
    • 0025326074 scopus 로고
    • Albright's hereditary osteodystrophy and defective G-proteins
    • Spiegel AM Albright's hereditary osteodystrophy and defective G-proteins New England Journal of Medicine 322 1990 1461 1462
    • (1990) New England Journal of Medicine , vol.322 , pp. 1461-1462
    • Spiegel, AM1
  • 48
    • 0025865247 scopus 로고
    • gsp mutations in human thyroid tumours
    • Suarez HG du Villard JA Caillou B gsp mutations in human thyroid tumours Oncogene 6 1991 677 679
    • (1991) Oncogene , vol.6 , pp. 677-679
    • Suarez, HG1    du Villard, JA2    Caillou, B3
  • 49
    • 0023576039 scopus 로고
    • Identification of receptor contact site involved in receptor-G-protein coupling
    • Sullivan KA Miller RT Masters SB Identification of receptor contact site involved in receptor-G-protein coupling Nature (London) 330 1987 758 760
    • (1987) Nature (London) , vol.330 , pp. 758-760
    • Sullivan, KA1    Miller, RT2    Masters, SB3
  • 51
    • 0023522307 scopus 로고
    • Altered Gs and adenylate cyclase activity in human GHsecreting pituitary adenomas
    • s and adenylate cyclase activity in human GHsecreting pituitary adenomas Nature (London) 330 1987 566 568
    • (1987) Nature (London) , vol.330 , pp. 566-568
    • Vallar, L1    Spada, A2    Giannattasio, G3
  • 52
    • 0027411213 scopus 로고
    • Pertussis toxin-sensitive activation of p21ras by G-protein-coupled receptor agonists in fibroblasts
    • ras by G-protein-coupled receptor agonists in fibroblasts Proceedings of the National Academy of Sciences of the USA 90 1993 1257 1261
    • (1993) , pp. 1257-1261
    • van Corven, EJ1    Hordijk, PL2    Medema, RH3
  • 53
    • 0027489301 scopus 로고
    • G-protein mutations in human disease
    • Weinstein LS Shenker A G-protein mutations in human disease Clinical Chemistry 26 1993 333 338
    • (1993) Clinical Chemistry , vol.26 , pp. 333-338
    • Weinstein, LS1    Shenker, A2
  • 54
    • 0025195106 scopus 로고
    • Mutations of the Gsα subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis
    • sα subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis Proceedings of the National Academy of Sciences of the USA 87 1990 8287 8290
    • (1990) , pp. 8287-8290
    • Weinstein, LS1    Gejman, PV2    Friedman, E3
  • 55
    • 0026003074 scopus 로고
    • Activating mutations of the stimulatory G-protein in the McCune—Albright syndrome
    • Weinstein LS Shenker A Gejman PV Activating mutations of the stimulatory G-protein in the McCune—Albright syndrome New England Journal of Medicine 325 1991 1688 1695
    • (1991) New England Journal of Medicine , vol.325 , pp. 1688-1695
    • Weinstein, LS1    Shenker, A2    Gejman, PV3
  • 56
    • 0026672057 scopus 로고
    • A heterozygous 4-bp deletion mutation in the Gs alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy
    • s alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy Genomics 13 1992 1319 1321
    • (1992) Genomics , vol.13 , pp. 1319-1321
    • Weinstein, LS1    Gejman, PV2    de Mazancourt, P3
  • 57
    • 0027240231 scopus 로고
    • Involvement of ras and raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase
    • i-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase Journal of Biological Chemistry 268 1993 19196 19199
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 19196-19199
    • Winitz, S1    Russell, M2    Qian, N-X3
  • 58
  • 59
    • 0027217195 scopus 로고
    • A mutant a subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells
    • 12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells Proceedings of the National Academy of Sciences of the USA 90 1993 6741 6745
    • (1993) , pp. 6741-6745
    • Xu, N1    Bradley, L2    Ambdukar, I3    Gutkind, JS4
  • 60
    • 0027325891 scopus 로고
    • Rare mutations of the Gs alpha subunit gene in human endocrine tumors
    • Yoshimoto K Iwahana H Fukada Rare mutations of the Gs alpha subunit gene in human endocrine tumors Cancer 72 1993 1386 1393
    • (1993) Cancer , vol.72 , pp. 1386-1393
    • Yoshimoto, K1    Iwahana, H2    Fukada3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.