Enzymatic synthesis of capsaicin analogs with liver acetone powder

Tetrahedron Letters

Volumn 37, Issue 16, 1996, Pages 2789-2790

  Kobata, Kenji ^a   Yoshikawa, Koichi ^a   Kohashi, Masahiro ^a   Watanabe, Tatsuo ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; ENZYME ACTIVITY; LIVER; REACTION ANALYSIS; TECHNIQUE;

EID: 0029919683     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00429-7     Document Type: Article

References (11)

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10. Preparation of the HPLC sample: after centrifuging of the reaction mixture at 3000 rpm for 5 min, one μl of the upper layer was injected. HPLC conditions: column, Wakopak 5C18 AR, 48 x 150 mm (Wako Pure Chem. Ind., Osaka, Japan); eluent, methanol; flow rate, 0.5 ml/min; detection, UV 280 nm.
11. 3): 6.81 (1H, d, J= 8.4 Hz), 6.76 (1H, s), 6.71 (1H, d, J= 8.4 Hz), 5.60 (1H, bt), 5.56 (1H, s), 4.31 (2H, d, J= 6.0 Hz), 3.83 (3H, s), 2.14 (2H, t, J= 7.6 Hz), 1.60 (2H, quint, J= 7.6 Hz), 1.20 (20H, s), 0.83 (3H, t, J= 7.6 Hz).