A practical synthesis of (S)-(-)-nadifloxacin: Novel acid-catalyzed racemization of tetrahydroquinaldine derivative

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 4, 1996, Pages 642-645

  Hashimoto, Koji ^a   Okaichi, Yoshihiko ^a   Nomi, Daisuke ^a   Miyamoto, Hisashi ^a   Bando, Masahiko ^a   Kido, Masaru ^a   Fujimura, Tsutomu ^a   Furuta, Takuya ^a   Minamikawa, Jun Ichi ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

(S) ( ) nadifloxacin; acidic racemization; antibacterial agent; optical resolution; tetrahydroquinaldine

Indexed keywords

MESYLIC ACID; NADIFLOXACIN; TETRAHYDROQUINAZOLINE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CATALYSIS; CRYSTALLIZATION; DRUG SYNTHESIS; ENANTIOMER; NONHUMAN; PROPIONIBACTERIUM ACNES; REACTION ANALYSIS;

EID: 0029919583     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.642     Document Type: Article

References (12)

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