Basic fibroblast growth factor and PDGF in GI diseases

Bailliere's Clinical Gastroenterology

Volumn 10, Issue 1, 1996, Pages 97-112

  Szabo, Sandor ^a   Sandor, Zsuzsa ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CIMETIDINE; FIBROBLAST GROWTH FACTOR RECEPTOR; MERCAPTAMINE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR; SUCRALFATE;

BIOCHEMISTRY; CHRONIC GASTRITIS; CLINICAL TRIAL; DUODENUM ULCER; EROSIVE GASTRITIS; GASTROINTESTINAL DISEASE; GASTROINTESTINAL TUMOR; HUMAN; IMMUNOHISTOCHEMISTRY; INTRAGASTRIC DRUG ADMINISTRATION; MOLECULAR BIOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; STOMACH ACID SECRETION; STOMACH PROTECTION; STOMACH ULCER; SUBCUTANEOUS DRUG ADMINISTRATION; ULCER HEALING; ULCERATIVE COLITIS;

EID: 0029919577     PISSN: 09503528     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0950-3528(96)90042-1     Document Type: Article

References (68)

1. Antoniades HN & Hunkapiller MW (1983) Human platelet-derived growth factor (PDGF): amino terminal amino acid sequence. Science 220: 963-965.
2. Baird A & Klagsbrun M (1991) The fibroblast growth factor family. Cancer Cells, Volume 3, pp 239-243.
3. Basilico C & Moscatelli D (1992) The FGF family of growth factors and oncogenes. Advances in Cancer Research 59: 115-165.
4. Betsholtz C, Johnson A, Heldin CH et al (1986) cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumor cell lines. Nature 320: 695-699.
5. Chait A, Ross R, Albers JJ & Bierman EL (1980) Platelet-derived growth factor stimulates activity of low density lipoprotein receptors. Proceedings of the National Academy of Sciences of the USA 77: 4084-4088.
6. Doolittle RF, Hunkapiller MW, Hood LE et al (1983) Simian sarcoma virus one gene, v-sis, is derived from the gene (or genes) encoding platelet derived growth factor. Science 221: 275-277.
7. Dupuy D, Raza A & Szabo S (1989) The role of endogenous nonprotein and protein sulfhydryls in gastric mucosal injury and protection. In Szabo S & Pfeiffer CJ (eds) Ulcer Disease: New Aspects of Pathogenesis and Pharmacology, pp 421-434. Boca Raton, FL: CRC Press.
8. Eastman A, Rall L, Hammacher A et al (1988) Synthesis and assembly of a functionally active recombinant platelet derived growth factor AB heterodimer. Journal of Biological Chemistry 263: 16202-16208.
9. Eastman A, Andersson M, Betsholtz C et al (1991) Identification of a cell retention signal in the B-chain of PDGF and in the long splice version of the A-chain. Cellular Regulation 2: 503-512.
10. Florkiewicz RZ & Sommer A (1989) The human bFGF gene encodes four polypeptides: three initiate translation from non-ATG codons. Proceedings of the National Academy of Sciences of the USA 86: 3978-3981.
11. Folkman J, Szabo S, Stovroff M, McNeil P, Li W & Shing Y (1991) Duodenal ulcer: discovery of a new mechanism and development of angiogenic therapy which accelerates healing. Annals of Surgery 214: 414-426.
12. Givol D & Yayon A (1992) Complexity of FGF receptors: genetic basis for structural diversity and functional specificity. FASEB Journal 6: 3362-3369.
13. Gospodarowitz D, Bialecki H & Greenburg GJ (1978) Purification of the fibroblast growth factor activity factor from bovine brain. Journal of Biological Chemistry 253: 3736-3743.
14. Guglietta A, Hervada T, Nardi RV & Lesh CA (1992) Effect of platelet-derived growth factor-BB on indomethacin-induced gastric lesions in rats. Scandinavian Journal of Gastroenterology 27: 673-676.
15. Heldin CH & Westermark B (1990) Platelet-derived growth factor: mechanism of action and possible in vivo function. Cellular Regulation 1: 555-566.
16. Inui H, Kitami Y, Tani M et al (1994) Differences in signal transduction between platelet derived growth factor (PDGF) α and β receptors in vascular smooth muscle cells. Journal of Biological Chemistry 269: 30546-30552.
17. Johnson A, Heldin CH, Wasteson A et al (1984) The c-sis gene encodes a precursor of the beta chain of platelet derived growth factor. EMBO Journal 3: 921-928.
18. Khachigan LM, Owemsby DA & Chesterman CN (1992) A tyrosinated peptide representing the alternatively spliced exon of the platelet-derived growth factor A-chain binds specifically to cultured cells and interferes with binding to several growth factors. Journal of Biological Chemistry 267: 1660-1666.
19. Klagsbrun M (1989) The fibroblast growth factor family: structural and biological properties. Progress in Growth Factor Research. 1: 207-235.
20. Kohler N & Lipton A (1974) Platelet as a source of fibroblast growth-promoting activity. Experimental Cellular Research 87: 297-301.
21. Konturek SJ, Brzozowski T, Majka J et al (1993) Fibroblast growth factor in gastroprotection and ulcer healing: interaction with sucralfate. Gut 34: 881-887.
22. Kusstatcher S & Szabo S (1993) Effect of platelet derived growth factor (PDGF) on the healing of chronic gastritis in rats. Gastroenterology 104: A125.
23. Kusstatcher S, Nagy L, Morales RE & Szabo S (1992) Additive effect of basic fibroblast growth factor (bFGF) and cimetidine on chronic duodenal ulcer healing in rats. Gastroenterology 102: A104.
24. Kusstatcher S, Bishop J, Brown L et al (1993) Basic fibroblast growth factor (bFGF) immunolocalization in duodenum of normal rats after duodenal ulcer induction. Gastroenterology 104: A125.
25. Kusstatcher S, Sandor Z, Satoh H & Szabo S (1994) Inhibition of endogenous basic fibroblast growth factor (bFGF) delays duodenal ulcer healing in rats: implications for a physiologic role of bFGF. Gastroenterology 106: A113.
26. Langberg CW, Martin HJ, Sung CC & Kane CJM (1994) Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation. Radiotherapy and Oncology 32: 29-36.
27. Martinet Y, Rom WN, Grotendorst et al (1987) Exaggerated spontaneous release of platelet derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis. New England Journal of Medicine 317: 202-209.
28. Miller JP & Fargher EB (1986) Relapse of duodenal ulcer: does it matter which drug is used in initial treatment? British Medical Journal 293: 117-118.
29. Miyamoto M, Naruo K, Seko C et al (1993) Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property. Molecular and Cellular Biology 13: 4251-4259.
30. Nguyen M, Watanabe H, Budson AE et al (1994) Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers. Journal of the National Cancer Institute 86: 356-361.
31. Ohtani H, Nakamura S, Watanabe Y et al (1993) Immunocytochemical localization of basic fibroblast growth factor in carcinomas and inflammatory lesions of the human digestive tract. Laboratory Investigation 68: 520-527.
32. Östman A, Rall L, Hammacher A et al (1988) Synthesis and assembly of a functionally active recombinant platelet-derived growth-factor AB heterodimer. Journal of Biological Chemistry 263: 16202-16208.
33. Owen AJ, Geyer RP & Antoniades HN (1982) Human platelet-derived growth factor stimulates amino acid transport and protein synthesis by human diploid fibroblast in plasma-free media. Proceedings of the National Academy of Sciences of the USA 79: 3203-3207.
34. Partanen J, Makela YP, Earola E et al (1991) FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO Journal 10: 1347-1354.
35. Poulsen SS, Olsen KS & Kirkegaard P (1985) Healing of cysteamine-induced duodenal ulcers in rats. Digestive Disease and Science 30: 161-167.
36. Prats H, Kaghad M, Prats AC et al (1989) High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proceedings of the National Academy of Sciences of the USA 86: 1836-1840.
37. Raines EW & Ross R (1992) Compartmentalization of PDGF on extracellular binding sites dependent on exon-6-encoded sequences. Journal of Cellular Biology 116: 533-543.
38. Renko M, Quarto N, Morimoto T & Rifkin DB (1990) Nuclear and cytoplasmatic localization of different basic fibroblast growth factor species. Journal of Cell Physiology 144: 108-114.
39. Ross R (1988) The pathogenesis of atherosclerosis: an update. New England Journal of Medicine 314: 488-500.
40. Ross R, Glomset J, Kariya B & Harker L (1974) A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proceedings of the National Academy of Sciences of the USA 71: 1207-1210.
41. Sakoulas G, Kusstatcher S, Ku PT et al (1993) Role of endogenous basic fibroblast growth factor in duodenal ulceration. Digestive Disease and Science 38: A11.
42. Sandor Z, Nagata M, Kusstatscher S & Szabo S (1994) New animal model of ulcerative colitis associated with depletion of glutathione and protein SH alkylation. Gastroenterology 106(4): A766.
43. Sandor Z, Kusstatcher S, Szeli D & Szabo S (1995a) Effect of platelet-derived growth factor in experimental colitis in rats. Orvosi Hetilap 136(20): 1059-1061.
44. Sandor Z, Szeli D, Charette M & Szabo S (1995b) Platelet-derived growth factor (PDGF) accelerates the healing of experimental ulcerative colitis in rats. Gastroenterology 108(4): A887.
45. Satoh H & Szabo S (1990) New animal model of ulcerative colitis induced by sulfhydryl blockers in the rat. Gastroenterology 98: A202 (abstract).
46. Satoh H, Shino A, Inatomi N et al (1991) Effect of rhbFGF mutein CS23 (TGP-580) on the healing of gastric ulcers induced by acetic acid in rats. Gastroenterology 100: A155.
47. Satoh H, Shino A, Sato F et al (1992) Role of endogenous and exogenous bFGF in the healing of gastric ulcers in rats. Gastroenterology 102: A159.
48. Seno K, Sasada R, Iwane K et al (1988) Stabilizing basic fibroblast growth factor using protein engineering. Biochemistry and Biophysical Research Communications 151: 701-708.
49. Shing Y, Folkman J, Sullivan R et al (1984) Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor. Science 223: 1296-1299.
50. Stovroff M, Vattay P, Marino B et al (1991) Healing of experimental gastritis by oral fibroblast growth factor. Surgical Forum 42: 174-175.
51. Summer A, Moscatelli D & Rifkin DB (1989) An amino terminally extended and post translationally modified form of a 25kDa basic fibroblast growth factor. Biochemistry and Biophysical Research Communications 160: 1267-1274.
52. Szabo S (1978) Animal model of human disease: duodenal ulcer disease. Animal model: cysteamine-induced acute and chronic duodenal ulcer in the rat. American Journal of Pathology 93: 273-276.
53. Szabo S (1991) The mode of action of sucralfate: the 1×1×1 mechanism of action. Scandinavian Journal of Gastroenterology 26 (supplement 85): 7-12.
54. Szabo S & Pfeiffer CJ (eds) (1989) Ulcer Disease: New Aspects of Pathogenesis and Pharmacology. Boca Raton, FL: CRC Press.
55. Szabo S, Trier JS & Frankel PW (1981) Sulphydryl compounds may mediate gastric cytoprotection. Science 214: 200-202.
56. Szabo S, Trier JS, Brown A & Schnoor M (1984) Sulfhydryl blockers induce severe inflammatory gastritis in the rat. Gastroenterology 86: A1271.
57. Szabo S, Folkman J, Vattay P et al (1991a) Duodenal ulcerogens: the effect of FGF on cysteamine-induced duodenal ulcer. In Halter F, Garner A & Tytgat GNJ (eds) Mechanisms of Peptic Ulcer Healing, pp 139-150. London: Kluwer Academic Publishers.
58. Szabo S, Vattay P, Scarbrough E & Folkman J (1991b) Role of vascular factors, including angiogenesis in the mechanisms of action of sucralfate. American Journal of Medicine 91 (supplement 2A): S158-S160.
59. Szabo S, Sakoulas G, Kusstatcher S & Sandor Z (1993) Effects of endogenous and exogenous basic fibroblast growth factor in ulcer healing. European Journal of Gastroenterology 5 (supplement 3): S53-S57.
60. Szabo S, Folkman J, Vattay et al (1994) Accelerated healing of duodenal ulcers by oral administration of mutein of fibroblast growth factor in rats. Gastroenterology 106: 1106-1111.
61. Szabo S, Kusstatsher S, Sandor Z & Sakoulas G (1995) Molecular and cellular basis of ulcer healing. Scandinavian Journal of Gastroenterology 30 (supplement 208): 3-8.
62. Tanaka A, Miyamoto K, Minamino N et al (1992) Cloning and characterization of an androgen-induced growth factor essential for the androgen dependent growth of mouse mammary carcinoma cells. Proceedings of National Academy of Sciences of the USA 89: 8928-8932.
63. Thyberg J, Eastman A, Backstrom G et al (1990) Localization of platelet-derived growth factor (PDGF) in CHO cells transfected with PDGF A- or B-chain cDNA: retention of PDGF-BB in the cytoplasmic reticulum and Golgi complex. Journal of Cellular Science 97: 219-229.
64. Vattay P, Gambier E, Morales RE & Kate K (1991) Effect of orally administered platelet-derived growth factor (PDGF) on healing of chronic duodenal ulcers and gastric secretion in rats. Gastroenterology 100: A180.
65. Watanabe S, Maehiro K, Hirose M et al (1994) Modulation of gastric mucosal restoration by growth factors in a culture cell model. Gastroenterology 106: A209.
66. Westermark B & Heldin CH (1991) Platelet-derived growth factor in autocrine transformation. Cancer Research 51: 5087-5092.
67. Wolfe MM, Bynum TE, Parson WG et al (1994) Safety and efficacy of an angiogenic peptide, basic fibroblast growth factor (bFGF), in treatment of gastroduodenal ulcers: a preliminary report. Gastroenterology 106: A212.
68. Yayon A, Klagsbrun M, Esko JD et al (1991) Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell 64: 841-848.